FR2375250A1 - 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques - Google Patents

3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques

Info

Publication number
FR2375250A1
FR2375250A1 FR7739221A FR7739221A FR2375250A1 FR 2375250 A1 FR2375250 A1 FR 2375250A1 FR 7739221 A FR7739221 A FR 7739221A FR 7739221 A FR7739221 A FR 7739221A FR 2375250 A1 FR2375250 A1 FR 2375250A1
Authority
FR
France
Prior art keywords
methylfortimicins
antibiotics
preparation
therapeutic use
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7739221A
Other languages
English (en)
Other versions
FR2375250B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2375250A1 publication Critical patent/FR2375250A1/fr
Application granted granted Critical
Publication of FR2375250B1 publication Critical patent/FR2375250B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveaux composés répondant à la formule générale :
FR7739221A 1976-12-27 1977-12-26 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques Granted FR2375250A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/754,670 US4124756A (en) 1976-12-27 1976-12-27 3-DE-O-Methylfortimicins

Publications (2)

Publication Number Publication Date
FR2375250A1 true FR2375250A1 (fr) 1978-07-21
FR2375250B1 FR2375250B1 (fr) 1980-04-04

Family

ID=25035809

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7739221A Granted FR2375250A1 (fr) 1976-12-27 1977-12-26 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques

Country Status (13)

Country Link
US (1) US4124756A (fr)
JP (1) JPS6011719B2 (fr)
AR (1) AR223456A1 (fr)
AU (1) AU517514B2 (fr)
BE (1) BE862299A (fr)
CA (1) CA1089851A (fr)
DE (1) DE2758165A1 (fr)
FR (1) FR2375250A1 (fr)
GB (2) GB1598704A (fr)
GR (1) GR64125B (fr)
NL (1) NL7714329A (fr)
PH (1) PH14711A (fr)
SE (1) SE7714792L (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2452497A1 (fr) * 1979-03-29 1980-10-24 Abbott Lab Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques
FR2452495A1 (fr) * 1979-03-29 1980-10-24 Abbott Lab 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation
EP0048549A1 (fr) * 1980-09-11 1982-03-31 Zaidanhojin Biseibutsu Kagaku Kenkyukai Dérivés 3-O-déméthyl de composés de la série de l'istamycine B et leur préparation

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR66054B (fr) * 1976-10-28 1981-01-14 Abbott Lab
JPS53141244A (en) * 1977-05-11 1978-12-08 Kyowa Hakko Kogyo Co Ltd Novel hortemycin derivatives
JPS5466679A (en) * 1977-11-07 1979-05-29 Kyowa Hakko Kogyo Co Ltd Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
JPS5488240A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
JPS6041679B2 (ja) * 1978-03-03 1985-09-18 協和醗酵工業株式会社 新抗生物質ホ−テイマイシンｋｇ↓１，ｋｇ↓２およびｋｇ↓３ならびにそれらの製造法
SE447386B (sv) * 1978-10-18 1986-11-10 Kowa Co Aminoglykosider, komposition innehallande dem samt forfarande for framstellning av dem
US4226980A (en) * 1978-12-07 1980-10-07 Abbott Laboratories Novel derivatives of fortimicin B and process for preparing same
US4239752A (en) * 1979-03-29 1980-12-16 Abbott Laboratories O-Demethylseldomycin factor 5 derivatives
US4242503A (en) * 1979-03-29 1980-12-30 Abbott Laboratories Process for O-demethylating fortimicins
US4214080A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicins AM and AP
US4218442A (en) * 1979-03-29 1980-08-19 Abbott Laboratories 1-Epi-fortimicin A and derivatives
US4213972A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI
US4213971A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AD derivatives
US4218441A (en) * 1979-03-29 1980-08-19 Abbott Laboratories O-Demethylseldomycin factor 5
BE882501A (fr) * 1979-03-29 1980-09-29 Abbott Lab 2-epifortimicine a et derives, et leurs applications therapeutiques
US4216210A (en) * 1979-03-29 1980-08-05 Abbott Laboratories Fortimicins AM and AP derivatives
US4219642A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AO
US4220756A (en) * 1979-03-29 1980-09-02 Abbott Laboratories Method of producing 3-O-demethylfortimicin B,4-N-alkylfortimicin B derivatives and related aminoglycoside antibiotics
US4213974A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives
US4330673A (en) * 1979-03-29 1982-05-18 Abbott Laboratories Process for producing 3-O-demethylaminoglycoside and novel 3-O-demethylfortimicin derivatives
US4214078A (en) * 1979-03-29 1980-07-22 Abbott Laboratories Fortimicin AL
US4230848A (en) * 1979-03-29 1980-10-28 Abbott Laboratories Process for producing 3-O-demethylfortimicins
US4214079A (en) * 1979-03-29 1980-07-22 Abbott Laboratories 4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives
US4219644A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicins AH and AI
US4226979A (en) * 1979-03-29 1980-10-07 Abbott Laboratories Fortimicin AK
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4251516A (en) * 1979-09-26 1981-02-17 Abbott Laboratories 2-Deoxy-3-O-Demethylfortimicins
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4283529A (en) * 1980-03-03 1981-08-11 Abbott Laboratories 3-O-Demethyl derivatives of Sannamycin C and antibiotic AX-127B-1
US4515941A (en) * 1982-04-07 1985-05-07 Toyo Jozo Kabushiki Kaisha 23-Demycinosyldesmycosin derivatives
US4423210A (en) * 1982-04-09 1983-12-27 Abbott Laboratories Intermediates for the preparation of 3-demethoxyfortimicins
US4427662A (en) 1982-04-09 1984-01-24 Abbott Laboratories 3-Amino-3-demethoxyfortimicins, pharmaceutical compositions thereof and method of use
JPS63152394A (ja) * 1987-11-18 1988-06-24 Kowa Co 新規なアミノ酸糖体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL291070A (fr) * 1962-04-03
US3792037A (en) * 1971-11-04 1974-02-12 Bristol Myers Co Process for preparing ambutyrosin
JPS5220991B2 (fr) * 1972-08-23 1977-06-07
US3985727A (en) * 1975-03-28 1976-10-12 Schering Corporation Aminoglycoside antibiotics

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2452497A1 (fr) * 1979-03-29 1980-10-24 Abbott Lab Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques
FR2452495A1 (fr) * 1979-03-29 1980-10-24 Abbott Lab 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation
EP0048549A1 (fr) * 1980-09-11 1982-03-31 Zaidanhojin Biseibutsu Kagaku Kenkyukai Dérivés 3-O-déméthyl de composés de la série de l'istamycine B et leur préparation

Also Published As

Publication number Publication date
GB1598705A (en) 1981-09-23
SE7714792L (sv) 1978-06-28
BE862299A (fr) 1978-06-23
AU3129277A (en) 1979-06-14
AU517514B2 (en) 1981-08-06
FR2375250B1 (fr) 1980-04-04
US4124756A (en) 1978-11-07
AR223456A1 (es) 1981-08-31
GR64125B (en) 1980-01-25
CA1089851A (fr) 1980-11-18
NL7714329A (nl) 1978-06-29
DE2758165A1 (de) 1978-07-06
PH14711A (en) 1981-11-13
GB1598704A (en) 1981-09-23
JPS5395943A (en) 1978-08-22
JPS6011719B2 (ja) 1985-03-27

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ST Notification of lapse