FR2375250A1 - 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques - Google Patents
3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiquesInfo
- Publication number
- FR2375250A1 FR2375250A1 FR7739221A FR7739221A FR2375250A1 FR 2375250 A1 FR2375250 A1 FR 2375250A1 FR 7739221 A FR7739221 A FR 7739221A FR 7739221 A FR7739221 A FR 7739221A FR 2375250 A1 FR2375250 A1 FR 2375250A1
- Authority
- FR
- France
- Prior art keywords
- methylfortimicins
- antibiotics
- preparation
- therapeutic use
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Nouveaux composés répondant à la formule générale :
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/754,670 US4124756A (en) | 1976-12-27 | 1976-12-27 | 3-DE-O-Methylfortimicins |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2375250A1 true FR2375250A1 (fr) | 1978-07-21 |
FR2375250B1 FR2375250B1 (fr) | 1980-04-04 |
Family
ID=25035809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7739221A Granted FR2375250A1 (fr) | 1976-12-27 | 1977-12-26 | 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques |
Country Status (13)
Country | Link |
---|---|
US (1) | US4124756A (fr) |
JP (1) | JPS6011719B2 (fr) |
AR (1) | AR223456A1 (fr) |
AU (1) | AU517514B2 (fr) |
BE (1) | BE862299A (fr) |
CA (1) | CA1089851A (fr) |
DE (1) | DE2758165A1 (fr) |
FR (1) | FR2375250A1 (fr) |
GB (2) | GB1598704A (fr) |
GR (1) | GR64125B (fr) |
NL (1) | NL7714329A (fr) |
PH (1) | PH14711A (fr) |
SE (1) | SE7714792L (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2452497A1 (fr) * | 1979-03-29 | 1980-10-24 | Abbott Lab | Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques |
FR2452495A1 (fr) * | 1979-03-29 | 1980-10-24 | Abbott Lab | 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation |
EP0048549A1 (fr) * | 1980-09-11 | 1982-03-31 | Zaidanhojin Biseibutsu Kagaku Kenkyukai | Dérivés 3-O-déméthyl de composés de la série de l'istamycine B et leur préparation |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR66054B (fr) * | 1976-10-28 | 1981-01-14 | Abbott Lab | |
JPS53141244A (en) * | 1977-05-11 | 1978-12-08 | Kyowa Hakko Kogyo Co Ltd | Novel hortemycin derivatives |
JPS5466679A (en) * | 1977-11-07 | 1979-05-29 | Kyowa Hakko Kogyo Co Ltd | Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation |
JPS5488241A (en) * | 1977-12-21 | 1979-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel fortimicin a derivative |
JPS5488240A (en) * | 1977-12-21 | 1979-07-13 | Kyowa Hakko Kogyo Co Ltd | Novel fortimicin a derivative |
JPS6041679B2 (ja) * | 1978-03-03 | 1985-09-18 | 協和醗酵工業株式会社 | 新抗生物質ホ−テイマイシンkg↓1,kg↓2およびkg↓3ならびにそれらの製造法 |
SE447386B (sv) * | 1978-10-18 | 1986-11-10 | Kowa Co | Aminoglykosider, komposition innehallande dem samt forfarande for framstellning av dem |
US4226980A (en) * | 1978-12-07 | 1980-10-07 | Abbott Laboratories | Novel derivatives of fortimicin B and process for preparing same |
US4239752A (en) * | 1979-03-29 | 1980-12-16 | Abbott Laboratories | O-Demethylseldomycin factor 5 derivatives |
US4242503A (en) * | 1979-03-29 | 1980-12-30 | Abbott Laboratories | Process for O-demethylating fortimicins |
US4214080A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | Fortimicins AM and AP |
US4218442A (en) * | 1979-03-29 | 1980-08-19 | Abbott Laboratories | 1-Epi-fortimicin A and derivatives |
US4213972A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | 4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI |
US4213971A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | 4-N, 2'-N and 4,2'-Di-N-fortimicin AD derivatives |
US4218441A (en) * | 1979-03-29 | 1980-08-19 | Abbott Laboratories | O-Demethylseldomycin factor 5 |
BE882501A (fr) * | 1979-03-29 | 1980-09-29 | Abbott Lab | 2-epifortimicine a et derives, et leurs applications therapeutiques |
US4216210A (en) * | 1979-03-29 | 1980-08-05 | Abbott Laboratories | Fortimicins AM and AP derivatives |
US4219642A (en) * | 1979-03-29 | 1980-08-26 | Abbott Laboratories | Fortimicin AO |
US4220756A (en) * | 1979-03-29 | 1980-09-02 | Abbott Laboratories | Method of producing 3-O-demethylfortimicin B,4-N-alkylfortimicin B derivatives and related aminoglycoside antibiotics |
US4213974A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | 4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives |
US4330673A (en) * | 1979-03-29 | 1982-05-18 | Abbott Laboratories | Process for producing 3-O-demethylaminoglycoside and novel 3-O-demethylfortimicin derivatives |
US4214078A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | Fortimicin AL |
US4230848A (en) * | 1979-03-29 | 1980-10-28 | Abbott Laboratories | Process for producing 3-O-demethylfortimicins |
US4214079A (en) * | 1979-03-29 | 1980-07-22 | Abbott Laboratories | 4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives |
US4219644A (en) * | 1979-03-29 | 1980-08-26 | Abbott Laboratories | Fortimicins AH and AI |
US4226979A (en) * | 1979-03-29 | 1980-10-07 | Abbott Laboratories | Fortimicin AK |
US4230846A (en) * | 1979-09-26 | 1980-10-28 | Abbott Laboratories | 1,5-Carbamates of fortimicin B and derivatives |
US4252972A (en) * | 1979-09-26 | 1981-02-24 | Abbott Laboratories | Fortimicin B-1,2:4,5-bis-carbamates |
US4251516A (en) * | 1979-09-26 | 1981-02-17 | Abbott Laboratories | 2-Deoxy-3-O-Demethylfortimicins |
US4232147A (en) * | 1979-09-26 | 1980-11-04 | Abbott Laboratories | 4-N-Acylfortimicin B-1,5-carbamates |
US4283529A (en) * | 1980-03-03 | 1981-08-11 | Abbott Laboratories | 3-O-Demethyl derivatives of Sannamycin C and antibiotic AX-127B-1 |
US4515941A (en) * | 1982-04-07 | 1985-05-07 | Toyo Jozo Kabushiki Kaisha | 23-Demycinosyldesmycosin derivatives |
US4423210A (en) * | 1982-04-09 | 1983-12-27 | Abbott Laboratories | Intermediates for the preparation of 3-demethoxyfortimicins |
US4427662A (en) | 1982-04-09 | 1984-01-24 | Abbott Laboratories | 3-Amino-3-demethoxyfortimicins, pharmaceutical compositions thereof and method of use |
JPS63152394A (ja) * | 1987-11-18 | 1988-06-24 | Kowa Co | 新規なアミノ酸糖体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL291070A (fr) * | 1962-04-03 | |||
US3792037A (en) * | 1971-11-04 | 1974-02-12 | Bristol Myers Co | Process for preparing ambutyrosin |
JPS5220991B2 (fr) * | 1972-08-23 | 1977-06-07 | ||
US3985727A (en) * | 1975-03-28 | 1976-10-12 | Schering Corporation | Aminoglycoside antibiotics |
-
1976
- 1976-12-27 US US05/754,670 patent/US4124756A/en not_active Expired - Lifetime
-
1977
- 1977-12-07 AU AU31282/77A patent/AU517514B2/en not_active Expired
- 1977-12-13 CA CA292,979A patent/CA1089851A/fr not_active Expired
- 1977-12-14 PH PH20559A patent/PH14711A/en unknown
- 1977-12-15 JP JP52150002A patent/JPS6011719B2/ja not_active Expired
- 1977-12-16 GR GR54995A patent/GR64125B/el unknown
- 1977-12-22 AR AR270477A patent/AR223456A1/es active
- 1977-12-23 GB GB53707/77A patent/GB1598704A/en not_active Expired
- 1977-12-23 BE BE183827A patent/BE862299A/fr not_active IP Right Cessation
- 1977-12-23 GB GB23631/77A patent/GB1598705A/en not_active Expired
- 1977-12-23 NL NL7714329A patent/NL7714329A/xx unknown
- 1977-12-26 FR FR7739221A patent/FR2375250A1/fr active Granted
- 1977-12-27 SE SE7714792A patent/SE7714792L/xx not_active Application Discontinuation
- 1977-12-27 DE DE19772758165 patent/DE2758165A1/de not_active Withdrawn
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2452497A1 (fr) * | 1979-03-29 | 1980-10-24 | Abbott Lab | Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques |
FR2452495A1 (fr) * | 1979-03-29 | 1980-10-24 | Abbott Lab | 2-epi-fortimicines a et b et leurs derives, utiles notamment comme antibiotiques, et intermediaires pour leur preparation |
EP0048549A1 (fr) * | 1980-09-11 | 1982-03-31 | Zaidanhojin Biseibutsu Kagaku Kenkyukai | Dérivés 3-O-déméthyl de composés de la série de l'istamycine B et leur préparation |
Also Published As
Publication number | Publication date |
---|---|
GB1598705A (en) | 1981-09-23 |
SE7714792L (sv) | 1978-06-28 |
BE862299A (fr) | 1978-06-23 |
AU3129277A (en) | 1979-06-14 |
AU517514B2 (en) | 1981-08-06 |
FR2375250B1 (fr) | 1980-04-04 |
US4124756A (en) | 1978-11-07 |
AR223456A1 (es) | 1981-08-31 |
GR64125B (en) | 1980-01-25 |
CA1089851A (fr) | 1980-11-18 |
NL7714329A (nl) | 1978-06-29 |
DE2758165A1 (de) | 1978-07-06 |
PH14711A (en) | 1981-11-13 |
GB1598704A (en) | 1981-09-23 |
JPS5395943A (en) | 1978-08-22 |
JPS6011719B2 (ja) | 1985-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |