FR2360305B1 - - Google Patents

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Publication number
FR2360305B1
FR2360305B1 FR7623835A FR7623835A FR2360305B1 FR 2360305 B1 FR2360305 B1 FR 2360305B1 FR 7623835 A FR7623835 A FR 7623835A FR 7623835 A FR7623835 A FR 7623835A FR 2360305 B1 FR2360305 B1 FR 2360305B1
Authority
FR
France
Prior art keywords
substd
opt
alkyl
alkenyl
forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7623835A
Other languages
French (fr)
Other versions
FR2360305A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILE DE FRANCE ETUDES SCIENTIFIQU
Original Assignee
ILE DE FRANCE ETUDES SCIENTIFIQU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ILE DE FRANCE ETUDES SCIENTIFIQU filed Critical ILE DE FRANCE ETUDES SCIENTIFIQU
Priority to FR7623835A priority Critical patent/FR2360305A1/en
Priority to MC771250A priority patent/MC1154A1/en
Priority to DE19772734270 priority patent/DE2734270A1/en
Priority to IN1165/CAL/77A priority patent/IN145473B/en
Priority to PT6686577A priority patent/PT66865B/en
Priority to ES461175A priority patent/ES461175A1/en
Priority to BG3704777A priority patent/BG36496A3/en
Priority to GR54066A priority patent/GR61351B/en
Priority to DE19772760414 priority patent/DE2760414C2/de
Priority to GB32117/77A priority patent/GB1571447A/en
Priority to YU188277A priority patent/YU40005B/en
Priority to BE1008313A priority patent/BE857350A/en
Priority to AU27507/77A priority patent/AU516033B2/en
Priority to OA56243A priority patent/OA05728A/en
Priority to GB44877/78A priority patent/GB1571278A/en
Priority to EG45577A priority patent/EG12716A/en
Priority to LU77897A priority patent/LU77897A1/xx
Priority to IE2409/80A priority patent/IE45647B1/en
Priority to AT569677A priority patent/AT358034B/en
Priority to US05/821,123 priority patent/US4186135A/en
Priority to RO9124577A priority patent/RO72963A/en
Priority to IE1600/77A priority patent/IE45646B1/en
Priority to NO772739A priority patent/NO152133C/en
Priority to SE7708849A priority patent/SE440776B/en
Priority to MW2077A priority patent/MW2077A1/en
Priority to CA283,994A priority patent/CA1114371A/en
Priority to DK346977A priority patent/DK152366C/en
Priority to CH956277A priority patent/CH629198A5/en
Priority to NL7708616A priority patent/NL172063C/en
Priority to IL52644A priority patent/IL52644A0/en
Priority to HUSO001195 priority patent/HU179064B/en
Priority to DD20042077A priority patent/DD133237A5/en
Priority to NZ18481677A priority patent/NZ184816A/en
Priority to ZA00774701A priority patent/ZA774701B/en
Priority to PL1977200066A priority patent/PL111071B1/en
Priority to JP9405677A priority patent/JPS5318570A/en
Priority to ZM6077A priority patent/ZM6077A1/en
Priority to JP9405777A priority patent/JPS5328181A/en
Priority to CS775179A priority patent/CS216246B2/en
Priority to FI772362A priority patent/FI63938C/en
Priority to SU772507701A priority patent/SU716523A3/en
Priority to PH20078A priority patent/PH22114A/en
Priority to AR26867377A priority patent/AR219709A1/en
Publication of FR2360305A1 publication Critical patent/FR2360305A1/en
Priority to US06/014,680 priority patent/US4268512A/en
Priority to US06/014,678 priority patent/US4248885A/en
Priority to US06/014,785 priority patent/US4255580A/en
Priority to US06/047,968 priority patent/US4323503A/en
Priority to US06/060,953 priority patent/US4306072A/en
Application granted granted Critical
Publication of FR2360305B1 publication Critical patent/FR2360305B1/fr
Priority to PH25426-AA priority patent/PH18629A/en
Priority to PH26025A priority patent/PH17710A/en
Priority to JP4547682A priority patent/JPS57167914A/en
Priority to IL66138A priority patent/IL66138A0/en
Priority to HK40482A priority patent/HK40482A/en
Priority to HK40382A priority patent/HK40382A/en
Priority to SE8206546A priority patent/SE453390B/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

2,3-Alkylenedioxybenzamides of formula (I) and their acid -addn. salts, quat. ammonium salts, oxides and optical isomers are new. In (I), A is 1-3C alkylene opt. substd by 1-4C alkyl, 2-4C alkenyl or 1-4C hydroxyalkyl. R is H, 1-4C alkyl or -B-NR1R2; B is a direct bond or a 1-3C alkylene gp. opt. substd. by 1-4C alkyl or 2-4C alkenyl; R1 is H, 1-4C alkyl, 2-4C alkenyl, 2-4C alkynyl, substd. alkyl, or forms a heterocyclic ring with B, and R2 is H, 1-4C alkyl, 2-4C alkenyl or alkynyl, substd. alkyl, an opt. substd. heterocyclic gp., or a phenyl, adamantyl, cycloalkyl, bicycloalkyl or cycloalkenyl gp. bonded directly to the N atom or via an opt. substd. alkylene chain, or NR1R2 is a heterocycle opt. contg. other heteroatoms (including NR'', where R'' is H- 1-4C alkyl, 2-4C alkenyl or alkynyl, phenyl, benzyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, adamantyl, bicycloalkyl or alkyl substd by OH, SH, acyl, thioacyl, alkoxy or alkylthio). - R' is H, 1-4c alkyl, 2-4C alkenyl or alkynyl, adamantyl, pyrimidinyl, pyrazinyl, diazepinyl, quinuclidinyl, azabicycloalkyl, diazabicycloalkyl, bicycloalkyl, or opt. substd. phenyl or aralkyl, or R'+B forms an opt. substd. heterocycle contg. a single N atom, or R'+R1 forms an opt. substd. heterocycle contg. two heteroatoms, X is H, halogen, OH, 1-4C alkoxy, 1-4C alkyl, amino opt. mono- or disubstd. by 1-4C alkyl, acyl, aralkyl, furyl, pyranyl or alkoxycacarbonyl, or forms an A' chain with Y. Y is as defined for X or is NO2, 1-4C alkylsulphonyl, adamantyl-sulphonyl, cycloalkyl sulphonyl or SO2NR3R'; R3 and R4 are H, 1-4C alkyl, 2-4C alkenyl, 2-4C alkynyl, phenyl, benzyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, cycloalkenylalkyl, bicycloalkyl, adamantyl, pyrimidinyl, pyrazinyl, or alkyl substd. by OH, SH, acyl, thioacyl, alkoxy or alkylthio, or NR3R4 is an opt. substd. heterocycle opt. congt. another heteroatom; or Y forms an A chain with X or Z. Z is as defined for X or is NO2, or forms an A chain with Y. A is a carbon chain opt. substd. or opt. interrupted by one or more opt. substd. heteroatoms. - Cpds. (I) have anxiolytic, antidepressant and antiemetic activity with little or no cataleptic activity. A typical cpd. of N-(1-allyl-2-pyrrolidinylmethyl)-7-methylsulphamoyl-1, 4-benzodioxan-5-carboxamide. In an example, this is prepd. from 1,4-benzodioxan-5-carboxylic acid.
FR7623835A 1976-08-04 1976-08-04 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS Granted FR2360305A1 (en)

Priority Applications (55)

Application Number Priority Date Filing Date Title
FR7623835A FR2360305A1 (en) 1976-08-04 1976-08-04 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS
MC771250A MC1154A1 (en) 1976-08-04 1977-07-11 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS
DE19772734270 DE2734270A1 (en) 1976-08-04 1977-07-29 SUBSTITUTED 2,3-ALKYLENE-BIS (OXY) BENZAMIDES, THE METHOD OF MANUFACTURING THEM AND THE MEDICINAL PRODUCTS CONTAINING THEM
IN1165/CAL/77A IN145473B (en) 1976-08-04 1977-07-29
PT6686577A PT66865B (en) 1976-08-04 1977-07-29 PROCESS FOR PREPARING NOVEL SUBSTITUTED 2,3-ALKYLENE BIS (OXY) BENZAMIDES AND DERIVATIVES THEREOF
ES461175A ES461175A1 (en) 1976-08-04 1977-07-29 Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
BG3704777A BG36496A3 (en) 1976-08-04 1977-07-29 Method for preparing substituted 2, 3- alkylene- bis- (oxy) benzamines
GR54066A GR61351B (en) 1976-08-04 1977-07-29 Preparation process of novel substituted 2,3-alkylene bis(oxy)benzamides and derivatives thereof
DE19772760414 DE2760414C2 (en) 1976-08-04 1977-07-29
GB32117/77A GB1571447A (en) 1976-08-04 1977-08-01 Substituted 2,3-alkyleneduoxybenzamides
YU188277A YU40005B (en) 1976-08-04 1977-08-01 Process for obtaining new substituted 2,3-alkylene-bis-(ox)-benzamides
BE1008313A BE857350A (en) 1976-08-04 1977-08-01 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDES SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS
AU27507/77A AU516033B2 (en) 1976-08-04 1977-08-01 Substituted 2, 3-alkylene bis (oxy) benzamide derivatives
OA56243A OA05728A (en) 1976-08-04 1977-08-01 Process for the preparation of novel substituted 2,3-alkylene-bis (oxy) benzamides and their derivatives
GB44877/78A GB1571278A (en) 1976-08-04 1977-08-01 2,3-alkylene bis(oxy)benzoic acids
EG45577A EG12716A (en) 1976-08-04 1977-08-02 Process for preparing of novel substituted 2,3 alkylene bis(oxy)benzamides
LU77897A LU77897A1 (en) 1976-08-04 1977-08-02
IE2409/80A IE45647B1 (en) 1976-08-04 1977-08-02 2,3-alkylene bis (oxy) benzoic acids
AT569677A AT358034B (en) 1976-08-04 1977-08-02 METHOD FOR PRODUCING NEW SUBSTITUTED 2,3-ALKYLENE-BIS (OXY) BENZAMIDES
US05/821,123 US4186135A (en) 1976-08-04 1977-08-02 Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
RO9124577A RO72963A (en) 1976-08-04 1977-08-02 PROCESS FOR THE PREPARATION OF 2,3-ALKOYLENE-BIS- (OXY) -BENZAMIDE DERIVATIVES
IE1600/77A IE45646B1 (en) 1976-08-04 1977-08-02 Novel substituted 2,3-alkylene bis (oxy) benzamides, their derivatives and processes for the preparation thereof
NO772739A NO152133C (en) 1976-08-04 1977-08-03 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 2,3-ALKYLENE-BIS-OXYBENZAMIDES
SE7708849A SE440776B (en) 1976-08-04 1977-08-03 SET TO MAKE SUBSTITUTED 2,3-ALKYLENE-BIS (OXO) BENZAMIDES
MW2077A MW2077A1 (en) 1976-08-04 1977-08-03 New substituted 2, 3-alkylene bis (oxy) benzamides their derivatives and process for their preparation
CA283,994A CA1114371A (en) 1976-08-04 1977-08-03 Substituted 2,3-alkylene bis (oxy) benzamides, their derivatives and preparation process
DK346977A DK152366C (en) 1976-08-04 1977-08-03 METHOD OF ANALOGUE FOR THE PREPARATION OF 2,3-ALKYLENE-BIS- (OXY) -BENZAMIDES OR DERIVATIVES THEREOF, AND 2,3-ALKYLENE-BIS (OXY) BENZOIC ACID FOR USE AS INTERMEDIATE FRENCH PRODUCT
CH956277A CH629198A5 (en) 1976-08-04 1977-08-03 PROCESS FOR THE PREPARATION OF NEW SUBSTITUTED 2,3-ALKYLENE-BIS (OXY) -BENZAMIDES.
NL7708616A NL172063C (en) 1976-08-04 1977-08-03 FORMED MEDICINE PREPARATION WITH PSYCHOFUNCTIONAL ACTION CONTAINING SUBSTITUTED 2,3-ALKYLENE DIOXYBENAMIDES, METHOD FOR PREPARING THE PREPARATION, AND METHOD FOR PREPARING THE ACTIVE PRODUCTION.
IL52644A IL52644A0 (en) 1976-08-04 1977-08-03 Novel 2,3-alkylene bis(oxy)benzamide derivatives,their preparation and pharmaceutical compositions containing them
HUSO001195 HU179064B (en) 1976-08-04 1977-08-03 Process for preparing 2,3-alkylene-bis-/oxy/-benzamides
DD20042077A DD133237A5 (en) 1976-08-04 1977-08-03 PROCESS FOR PREPARING NOVEL SUBSTITUTED 2,3-ALKYLENE BIS- (OXY) BENZAMIDES
NZ18481677A NZ184816A (en) 1976-08-04 1977-08-03 Substituted 2,3-alkylene-bis-(oxy)-benzamides and pharmaceutical compositions intermediate acids
ZA00774701A ZA774701B (en) 1976-08-04 1977-08-03 New substituted 2,3-alkylene bis(oxy benzamides,their derivatives and processes for their preparation
PL1977200066A PL111071B1 (en) 1976-08-04 1977-08-04 Proces for the preparation of novel substituted 2,3-alkylene-bis-/oxy/benzamides
JP9405677A JPS5318570A (en) 1976-08-04 1977-08-04 Novel substituted 2*33alkylenebis*oxy*benzamides* thier preparation and medical agent containing same as active ingredient
ZM6077A ZM6077A1 (en) 1976-08-04 1977-08-04 New substituted 2,3-alkylene bis (oxy) benzamides, their derivatives and processes for their preparation
JP9405777A JPS5328181A (en) 1976-08-04 1977-08-04 Production of nove substituted 2*33alkylenebis *oxy* benzoic acid
CS775179A CS216246B2 (en) 1976-08-04 1977-08-04 Method of making the substituted 2,3-alkylen-bis-+l oxy+pbenzamides
FI772362A FI63938C (en) 1976-08-04 1977-08-04 FRAMEWORK FOR THE FRAMEWORK OF THERAPEUTIC ANALYTICAL SUBSTITUTES OF 2,3-ALKYLENBIS (OXI) BENZENIDE
SU772507701A SU716523A3 (en) 1976-08-04 1977-08-04 Method of preparing derivatives of 2,3-alkylene-bis(hydroxy)benzamides or their optical isomers or their salts
PH20078A PH22114A (en) 1976-08-04 1977-08-04 New substituted 2,3-alkylene bis(oxy) benzamides, their derivatives, pharmaceutical compositions containing same and method of use thereof
AR26867377A AR219709A1 (en) 1976-08-04 1977-08-08 PROCEDURE FOR THE PREPARATION OF 2,3-ALQUILEN-BIS (OXI) BENZAMIDAS SUBSTITUTED
US06/014,680 US4268512A (en) 1976-08-04 1979-02-23 Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation
US06/014,678 US4248885A (en) 1976-08-04 1979-02-23 Substituted 2,3-alkylene bis(oxy) benzamides and derivatives to treat psychofunctional disorders
US06/014,785 US4255580A (en) 1976-08-04 1979-02-23 Substituted 2,3-alkylene bis (oxy) benzamides and derivatives
US06/047,968 US4323503A (en) 1976-08-04 1979-06-12 Substituted 2,3-alkylene di (oxy) benzamides and derivatives
US06/060,953 US4306072A (en) 1976-08-04 1979-07-26 Substituted 2,3-alkylene bis (oxy)-4,5 (or 5,6) azimido benzamides and derivatives thereof
PH25426-AA PH18629A (en) 1976-08-04 1981-03-25 Substituted 2,3-alkylene bis (oxy) benzoic acid derivatives
PH26025A PH17710A (en) 1976-08-04 1981-08-07 Process for producing 2,3-alkylene bis(oxy)benzamides
JP4547682A JPS57167914A (en) 1976-08-04 1982-03-19 Remedy active to central nervous system
IL66138A IL66138A0 (en) 1976-08-04 1982-06-25 Substituted 2,3-alkylene bis(oxy)benzoic acids
HK40482A HK40482A (en) 1976-08-04 1982-09-16 Substitudet 2,3-alkylenedioxybenzamides
HK40382A HK40382A (en) 1976-08-04 1982-09-16 2,3-alkylene bis(oxy) benzoic acids
SE8206546A SE453390B (en) 1976-08-04 1982-11-17 SUBSTITUTED 2,3-ALKYLENE-BIS (OXI) -BENIC ACIDS FOR USE AS INTERMEDIATES FOR THE PREPARATION OF THERAPEUTIC VALUES, SUBSTITUTED 2,3-ALKYLENE-BIS (OXY) -BENZYES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7623835A FR2360305A1 (en) 1976-08-04 1976-08-04 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS
DE19772734270 DE2734270A1 (en) 1976-08-04 1977-07-29 SUBSTITUTED 2,3-ALKYLENE-BIS (OXY) BENZAMIDES, THE METHOD OF MANUFACTURING THEM AND THE MEDICINAL PRODUCTS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2360305A1 FR2360305A1 (en) 1978-03-03
FR2360305B1 true FR2360305B1 (en) 1980-04-18

Family

ID=52850786

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7623835A Granted FR2360305A1 (en) 1976-08-04 1976-08-04 NEW 2,3-ALKYLENE BIS (OXY) BENZAMIDE SUBSTITUTES, THEIR DERIVATIVES AND THEIR PREPARATION METHODS

Country Status (4)

Country Link
JP (1) JPS5318570A (en)
DE (1) DE2734270A1 (en)
FR (1) FR2360305A1 (en)
GB (1) GB1571447A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8503055D0 (en) * 1985-06-19 1985-06-19 Astra Laekemedel Ab PIPERONYLCARBOXAMIDO DERIVATIVES
FR2586018B1 (en) * 1985-08-12 1988-03-25 Ile De France NOVEL BENZODIOXEPANNE, ITS SYNTHESIS PROCESS AND THERAPEUTIC APPLICATIONS
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
GB9027098D0 (en) * 1990-12-13 1991-02-06 Beecham Group Plc Pharmaceuticals

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1220056A (en) * 1967-02-21 1971-01-20 Fisons Pest Control Ltd Substituted benzodioxoles

Also Published As

Publication number Publication date
DE2734270C2 (en) 1990-06-21
JPS6117832B2 (en) 1986-05-09
GB1571447A (en) 1980-07-16
FR2360305A1 (en) 1978-03-03
DE2734270A1 (en) 1978-02-16
JPS5318570A (en) 1978-02-20

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