FR04C0013I2 - - Google Patents

Info

Publication number
FR04C0013I2
FR04C0013I2 FR04C0013C FR04C0013C FR04C0013I2 FR 04C0013 I2 FR04C0013 I2 FR 04C0013I2 FR 04C0013 C FR04C0013 C FR 04C0013C FR 04C0013 C FR04C0013 C FR 04C0013C FR 04C0013 I2 FR04C0013 I2 FR 04C0013I2
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR04C0013C
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR04C0013(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of FR04C0013I1 publication Critical patent/FR04C0013I1/fr
Application granted granted Critical
Publication of FR04C0013I2 publication Critical patent/FR04C0013I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FR04C0013C 1997-06-11 2004-05-04 Active FR04C0013I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11
PCT/IB1998/000839 WO1998056802A1 (fr) 1997-06-11 1998-05-29 Derives de homo-erythromycine -9-deoxo-9a-aza-9aa substitution en position 4

Publications (2)

Publication Number Publication Date
FR04C0013I1 FR04C0013I1 (fr) 2004-06-11
FR04C0013I2 true FR04C0013I2 (fr) 2005-10-21

Family

ID=21959336

Family Applications (1)

Application Number Title Priority Date Filing Date
FR04C0013C Active FR04C0013I2 (fr) 1997-06-11 2004-05-04

Country Status (50)

Country Link
US (4) US6420536B1 (fr)
EP (1) EP0988310B9 (fr)
JP (2) JP3315704B2 (fr)
KR (1) KR100396168B1 (fr)
CN (4) CN1172947C (fr)
AP (1) AP1231A (fr)
AR (1) AR013086A1 (fr)
AT (1) ATE251173T1 (fr)
AU (1) AU749816B2 (fr)
BG (1) BG64391B1 (fr)
BR (1) BRPI9810519B8 (fr)
CA (1) CA2293823C (fr)
CO (1) CO4950611A1 (fr)
CZ (1) CZ298556B6 (fr)
DE (2) DE69818665T2 (fr)
DK (1) DK0988310T3 (fr)
DZ (1) DZ2514A1 (fr)
EA (1) EA002441B1 (fr)
EG (1) EG24081A (fr)
ES (1) ES2205487T3 (fr)
FR (1) FR04C0013I2 (fr)
GT (1) GT199800077A (fr)
HK (3) HK1028048A1 (fr)
HN (1) HN1998000086A (fr)
HR (1) HRP980314B1 (fr)
HU (2) HU228005B1 (fr)
ID (1) ID22992A (fr)
IL (1) IL132809A0 (fr)
IS (1) IS1998B (fr)
LU (1) LU91076I9 (fr)
MA (1) MA24564A1 (fr)
ME (1) ME00876B (fr)
MY (1) MY123354A (fr)
NL (1) NL300150I2 (fr)
NO (1) NO316911B1 (fr)
NZ (2) NZ500660A (fr)
OA (1) OA11224A (fr)
PA (1) PA8452201A1 (fr)
PE (1) PE79699A1 (fr)
PL (1) PL191601B1 (fr)
PT (1) PT988310E (fr)
RS (1) RS49675B (fr)
SI (1) SI0988310T1 (fr)
SK (1) SK284171B6 (fr)
TN (1) TNSN98082A1 (fr)
TW (1) TW472060B (fr)
UA (1) UA67744C2 (fr)
UY (1) UY25040A1 (fr)
WO (1) WO1998056802A1 (fr)
ZA (1) ZA985017B (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
EP1779853A3 (fr) * 1997-09-10 2010-01-27 Merial Ltd. 9a-azalides en tant qu'agents anti-microbiens à usage vétérinaire
JP2001515865A (ja) * 1997-09-10 2001-09-25 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての９ａ−アザライド
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
EP1437360A3 (fr) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11-carbamates des macrolides antibactériens
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
CA2411293A1 (fr) * 1999-01-28 2000-07-28 Pfizer Products Inc. Nouveaux azalides et procede de fabrication
OA11876A (en) * 1999-05-18 2006-03-27 Pfizer Prod Inc Novel crystalline forms of a macrolide antibiotic.
HUP0201516A3 (en) * 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
AU6748500A (en) * 1999-08-24 2001-03-19 Abbott Laboratories 9a-azalides with antibacterial activity
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
US6608033B1 (en) * 1999-08-27 2003-08-19 Pfizer Inc. Treatment or prevention of coccidiosis
DE60003586T2 (de) * 2000-01-27 2004-01-08 Pfizer Products Inc., Groton Antibiotische azalid-zusammensetzungen
EP1276747A1 (fr) * 2000-04-27 2003-01-22 Pfizer Products Inc. Utilisation de compositions antibiotiques de type azalide pour traiter ou prevenir une infection d'origine bacterienne ou protozoaire chez les mammiferes
RU2263117C2 (ru) 2001-04-27 2005-10-27 Пфайзер Продактс Инк. Способ получения 4"-замещенных производных 9-деоксо-9а-аза-9а-гомоэритромицина а
WO2003011266A2 (fr) * 2001-08-01 2003-02-13 Pfizer Products Inc. Compositions antibiotiques azalides
EP1638549A4 (fr) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc Nouveaux agents antibacteriens
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US20070141086A1 (en) * 2003-11-21 2007-06-21 Ohara Michael K Use of antibiotics as vaccine adjuvants
RS52365B (en) * 2004-03-16 2012-12-31 Boehringer Ingelheim International Gmbh BENZOL DERIVATIVES SUBSTITUTED BY GLUCOPYRANOSIL, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS, THEIR USE AND THE PROCEDURE FOR THEIR PRODUCTION
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
US7767797B1 (en) * 2004-09-30 2010-08-03 Synovo Gmbh Macrocyclic compounds and methods of use thereof
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
EP1841437B1 (fr) * 2005-01-14 2009-04-29 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Azalides 9a-carbamoyle et thiocarbamoyle avec activite antipaludique
EP2214484A4 (fr) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc Procédé pour la préparation d'agents antibactériens macrolides
US8796232B2 (en) * 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
WO2012038372A1 (fr) 2010-09-20 2012-03-29 Novartis Ag Nouveau procédé de préparation de 9-déoxo-9a-aza-9a-homoérythromycine a modifiée dans le c-4'' du cycle cladinose par un groupe époxyde
US9145436B2 (en) * 2010-10-10 2015-09-29 Michael W. Burnet Anti-inflammatory macrolides
WO2013004116A1 (fr) * 2011-07-06 2013-01-10 洛阳惠中兽药有限公司 Dérivé de 9a-aza-9a-érythromycine c-3-substituée et 9-désoxydée
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
WO2013013834A1 (fr) 2011-07-27 2013-01-31 Farma Grs, D.O.O. Nouvelles formes cristallines de tulathromycine
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
WO2014152326A1 (fr) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Procédés pour traiter des maladies respiratoires et formulations pour la mise en œuvre de ceux-ci
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
EP3027634B1 (fr) * 2013-07-31 2018-03-21 Farma GRS, d.o.o. Procédé de préparation de tulathromycine
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普（天津）生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
FR3048612B1 (fr) * 2016-03-14 2020-10-02 Septeos Tulathromycine potentialisee
CN106046077B (zh) * 2016-08-04 2019-07-26 湖北美天生物科技股份有限公司 一种泰拉霉素a的合成方法
CN108003207B (zh) * 2017-12-19 2019-05-10 海门慧聚药业有限公司 制备泰拉霉素的方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
CA2064634C (fr) * 1991-04-04 1998-08-04 James V. Heck Derives de 9-desoxo-8a-aza-8a-homoerythromycine a modifies en positions 4"- et 8a
US5226958A (en) * 1991-04-11 1993-07-13 Pacemark, Inc. Sealant for pneumatic inner tubes and tubeless tires
EP0549040A1 (fr) * 1991-12-20 1993-06-30 Merck & Co. Inc. Méthodes pour fabriquer 4" dérivés de 9-désoxo-8a-aza-8a-alkyl-8a-homoérythromycin A
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
UA70972C2 (uk) 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків

Also Published As

Publication number Publication date
DK0988310T3 (da) 2003-12-15
BRPI9810519B1 (pt) 2012-02-22
MA24564A1 (fr) 1998-12-31
PA8452201A1 (es) 2000-05-24
EG24081A (en) 2008-05-11
BG103945A (en) 2000-07-31
US20020061858A1 (en) 2002-05-23
PL337505A1 (en) 2000-08-28
ME00876B (me) 2012-06-20
HK1028048A1 (en) 2001-02-02
KR20010013632A (ko) 2001-02-26
CN1243766C (zh) 2006-03-01
HUS1200028I1 (hu) 2016-08-29
ZA985017B (en) 1999-12-17
HUP0002209A2 (hu) 2000-12-28
IS5252A (is) 1999-11-16
BRPI9810519A (pt) 2000-09-19
UA67744C2 (uk) 2004-07-15
NL300150I1 (nl) 2004-08-02
AR013086A1 (es) 2000-12-13
EP0988310B9 (fr) 2006-03-08
CN1793155B (zh) 2010-05-12
ES2205487T3 (es) 2004-05-01
ID22992A (id) 1999-12-23
HRP980314B1 (en) 2004-04-30
CN101691390A (zh) 2010-04-07
PE79699A1 (es) 1999-08-25
KR100396168B1 (ko) 2003-08-27
NO996106D0 (no) 1999-12-10
HRP980314A2 (en) 1999-04-30
EP0988310B1 (fr) 2003-10-01
EA199901015A1 (ru) 2000-06-26
GT199800077A (es) 1999-12-02
TNSN98082A1 (fr) 2005-03-15
BRPI9810519B8 (pt) 2022-11-16
BG64391B1 (bg) 2004-12-30
AU7347598A (en) 1998-12-30
SK284171B6 (sk) 2004-10-05
CZ298556B6 (cs) 2007-11-07
JP3315704B2 (ja) 2002-08-19
DE122004000018I1 (de) 2004-09-30
HU228005B1 (en) 2012-08-28
LU91076I9 (en) 2018-07-02
EP0988310A1 (fr) 2000-03-29
FR04C0013I1 (fr) 2004-06-11
NZ500660A (en) 2002-03-01
EA002441B1 (ru) 2002-04-25
ATE251173T1 (de) 2003-10-15
CN1259136A (zh) 2000-07-05
CA2293823A1 (fr) 1998-12-17
US20040023896A1 (en) 2004-02-05
DE69818665D1 (de) 2003-11-06
DE122004000018I2 (de) 2011-01-13
PL191601B1 (pl) 2006-06-30
CN1566129A (zh) 2005-01-19
DZ2514A1 (fr) 2003-02-01
WO1998056802A1 (fr) 1998-12-17
SI0988310T1 (en) 2004-02-29
LU91076I2 (fr) 2004-07-05
HK1068893A1 (en) 2005-07-29
US6936592B2 (en) 2005-08-30
US20040180842A1 (en) 2004-09-16
MY123354A (en) 2006-05-31
CA2293823C (fr) 2004-02-17
IS1998B (is) 2005-03-15
AP1231A (en) 2003-12-11
YU58699A (fr) 2002-08-12
AU749816B2 (en) 2002-07-04
CN1172947C (zh) 2004-10-27
TW472060B (en) 2002-01-11
JP2002316933A (ja) 2002-10-31
IL132809A0 (en) 2001-03-19
JP2000514098A (ja) 2000-10-24
HN1998000086A (es) 1999-03-08
AP9801255A0 (en) 1998-06-30
NO316911B1 (no) 2004-06-21
NL300150I2 (nl) 2004-09-01
UY25040A1 (es) 2000-09-29
OA11224A (en) 2003-07-16
NZ514871A (en) 2003-08-29
DE69818665T2 (de) 2004-04-29
PT988310E (pt) 2003-12-31
US6420536B1 (en) 2002-07-16
CN1793155A (zh) 2006-06-28
US6777393B2 (en) 2004-08-17
SK168399A3 (en) 2000-11-07
RS49675B (sr) 2007-11-15
HK1088014A1 (en) 2006-10-27
CZ442199A3 (cs) 2000-07-12
CO4950611A1 (es) 2000-09-01
NO996106L (no) 2000-02-10
HUP0002209A3 (en) 2003-05-28

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