FI951009A - Muskariinin vastaisina aineina käyttökelpoisia diaryylipiperatsinoasetamidiyhdisteitä - Google Patents
Muskariinin vastaisina aineina käyttökelpoisia diaryylipiperatsinoasetamidiyhdisteitä Download PDFInfo
- Publication number
- FI951009A FI951009A FI951009A FI951009A FI951009A FI 951009 A FI951009 A FI 951009A FI 951009 A FI951009 A FI 951009A FI 951009 A FI951009 A FI 951009A FI 951009 A FI951009 A FI 951009A
- Authority
- FI
- Finland
- Prior art keywords
- diarylpiperazinoacetamide
- compounds useful
- muscarinic agents
- muscarinic
- agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92402435A EP0585500A1 (en) | 1992-09-04 | 1992-09-04 | Diaryl piperazineacetamides as antimuscarinic agents |
| PCT/US1993/007198 WO1994005648A1 (en) | 1992-09-04 | 1993-07-29 | Diaryl piperazinoacetamide compounds as antimuscarinic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI951009A true FI951009A (fi) | 1995-03-03 |
| FI951009A0 FI951009A0 (fi) | 1995-03-03 |
Family
ID=8211704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI951009A FI951009A0 (fi) | 1992-09-04 | 1995-03-03 | Muskariinin vastaisina aineina käyttökelpoisia diaryylipiperatsinoasetamidiyhdisteitä |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP0585500A1 (fi) |
| JP (1) | JPH08501096A (fi) |
| AU (1) | AU668413B2 (fi) |
| CA (1) | CA2143744A1 (fi) |
| FI (1) | FI951009A0 (fi) |
| HU (1) | HUT71890A (fi) |
| IL (1) | IL106878A0 (fi) |
| MX (1) | MX9305248A (fi) |
| NZ (1) | NZ255176A (fi) |
| TW (1) | TW281674B (fi) |
| WO (1) | WO1994005648A1 (fi) |
| ZA (1) | ZA936362B (fi) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859295A (en) * | 1994-12-05 | 1999-01-12 | University Of Kentucky Research Foundation | Canavanine analogs and their use as chemotherapeutic agents |
| IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| US5889006A (en) * | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
| GB9513972D0 (en) * | 1995-07-08 | 1995-09-06 | Merck Sharp & Dohme | Pharmaceutical compositions |
| PL334304A1 (en) * | 1996-12-24 | 2000-02-14 | Chugai Pharmaceutical Co Ltd | Derivatives of aromatic amines acting as nos inhibitors |
| GB9709972D0 (en) * | 1997-05-19 | 1997-07-09 | Pfizer Ltd | Tetrazoles |
| KR20010022147A (ko) * | 1997-07-24 | 2001-03-15 | 아사이 이페이 | 아미노시클로알칸 화합물 |
| AU3605299A (en) * | 1998-04-08 | 1999-11-01 | Novartis Ag | Novel herbicides |
| US6511980B2 (en) | 2000-05-05 | 2003-01-28 | Ortho Mcneil Pharmaceutical, Inc. | Substituted diamine derivatives useful as motilin antagonists |
| EP1469850B1 (en) | 2002-01-02 | 2013-01-02 | Versi Group, LLC | Method of treating sexual dysfunctions with delta opioid receptor agonist compounds |
| FR2840609A1 (fr) * | 2002-06-05 | 2003-12-12 | Lipha | Derives nitroso de la diphenylamine, compositions les contenant et leur utilisation en tant qu'antioxydants et donneurs spontanes d'oxyde nitrique |
| AU2003263402A1 (en) * | 2002-09-20 | 2004-04-08 | Pfizer Products Inc. | Amide and sulfonamide ligands for the estrogen receptor |
| ES2644450T3 (es) | 2004-12-31 | 2017-11-29 | Dr. Reddy's Laboratories Ltd. | Nuevos derivados de bencilamina como inhibidores de CETP |
| US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
| TWI498115B (zh) | 2007-12-27 | 2015-09-01 | Daiichi Sankyo Co Ltd | 咪唑羰基化合物 |
| GB0815781D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| WO2011000945A2 (en) | 2009-07-03 | 2011-01-06 | Nensius Research A/S | Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns |
| CA2845284C (en) | 2011-08-18 | 2018-03-06 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors |
| JP6140168B2 (ja) | 2011-09-27 | 2017-05-31 | ドクター レディズ ラボラトリーズ リミテッド | アテローム性動脈硬化症の処置のために有用なコレステリルエステル転送タンパク質（ｃｅｔｐ）インヒビターとしての５−ベンジルアミノメチル−６−アミノピラゾロ［３，４−ｂ］ピリジン誘導体 |
| SI3442947T1 (sl) * | 2016-04-15 | 2023-10-30 | Epizyme, Inc. | Z aminom substituirane arilne ali heteroarilne spojine kot inhibitorji ehmt1 in ehmt2 |
| EP3612181A4 (en) | 2017-04-21 | 2021-01-06 | Epizyme, Inc. | COMBINATION THERAPIES WITH EHMT2 INHIBITORS |
| TW202241856A (zh) * | 2020-12-28 | 2022-11-01 | 日商塩野義製藥股份有限公司 | 具有血清素受體結合活性之環狀胺衍生物 |
| WO2023018471A1 (en) * | 2021-08-10 | 2023-02-16 | Texas Heart Institute | Piperazine-based agonists of lfa-1 and vla-4 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU209723B (en) * | 1990-10-31 | 1994-10-28 | Richter Gedeon Vegyeszet | Process for producing of piperazine derivatives |
| US5276155A (en) * | 1991-12-20 | 1994-01-04 | G. D. Searle & Co. | Process for the resolution of (±)-α-[2-[acetyl(1-methylethyl)amino]ethyl]-α-(2-chlorophenyl)-1-piperidinebutanamide |
| DE4314962A1 (de) * | 1993-05-06 | 1994-11-10 | Bayer Ag | Substituierte Piperazine |
-
1992
- 1992-09-04 EP EP92402435A patent/EP0585500A1/en not_active Withdrawn
-
1993
- 1993-07-29 EP EP93918532A patent/EP0658157A1/en not_active Withdrawn
- 1993-07-29 WO PCT/US1993/007198 patent/WO1994005648A1/en not_active Application Discontinuation
- 1993-07-29 HU HU9500664A patent/HUT71890A/hu unknown
- 1993-07-29 AU AU47953/93A patent/AU668413B2/en not_active Ceased
- 1993-07-29 NZ NZ255176A patent/NZ255176A/en unknown
- 1993-07-29 JP JP6507184A patent/JPH08501096A/ja not_active Withdrawn
- 1993-07-29 CA CA002143744A patent/CA2143744A1/en not_active Abandoned
- 1993-08-30 ZA ZA936362A patent/ZA936362B/xx unknown
- 1993-08-30 MX MX9305248A patent/MX9305248A/es unknown
- 1993-08-31 TW TW082107092A patent/TW281674B/zh active
- 1993-09-02 IL IL106878A patent/IL106878A0/xx unknown
-
1995
- 1995-03-03 FI FI951009A patent/FI951009A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0585500A1 (en) | 1994-03-09 |
| EP0658157A1 (en) | 1995-06-21 |
| IL106878A0 (en) | 1993-12-28 |
| WO1994005648A1 (en) | 1994-03-17 |
| MX9305248A (es) | 1995-01-31 |
| NZ255176A (en) | 1996-02-27 |
| JPH08501096A (ja) | 1996-02-06 |
| AU668413B2 (en) | 1996-05-02 |
| HU9500664D0 (en) | 1995-04-28 |
| HUT71890A (en) | 1996-02-28 |
| AU4795393A (en) | 1994-03-29 |
| TW281674B (fi) | 1996-07-21 |
| CA2143744A1 (en) | 1994-03-17 |
| ZA936362B (en) | 1994-03-28 |
| FI951009A0 (fi) | 1995-03-03 |
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