FI935318A - 15-deoksispergualiinianalogit, menetelmä niiden valmistamiseksi ja niiden käyttö terapiassa - Google Patents

15-deoksispergualiinianalogit, menetelmä niiden valmistamiseksi ja niiden käyttö terapiassa Download PDF

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Publication number
FI935318A
FI935318A FI935318A FI935318A FI935318A FI 935318 A FI935318 A FI 935318A FI 935318 A FI935318 A FI 935318A FI 935318 A FI935318 A FI 935318A FI 935318 A FI935318 A FI 935318A
Authority
FI
Finland
Prior art keywords
pergualin
deoxy
analogues
therapy
processes
Prior art date
Application number
FI935318A
Other languages
English (en)
Swedish (sv)
Other versions
FI112211B (fi
FI935318A0 (fi
Inventor
Patrice Renaut
Luc Lebreton
Patrick Dutartre
Philippe Derrepas
Soth Samreth
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Publication of FI935318A0 publication Critical patent/FI935318A0/fi
Publication of FI935318A publication Critical patent/FI935318A/fi
Application granted granted Critical
Publication of FI112211B publication Critical patent/FI112211B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI935318A 1992-12-02 1993-11-29 Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet FI112211B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9214517A FR2698628B1 (fr) 1992-12-02 1992-12-02 Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR9214517 1992-12-02

Publications (3)

Publication Number Publication Date
FI935318A0 FI935318A0 (fi) 1993-11-29
FI935318A true FI935318A (fi) 1994-06-03
FI112211B FI112211B (fi) 2003-11-14

Family

ID=9436147

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935318A FI112211B (fi) 1992-12-02 1993-11-29 Menetelmä terapeuttisesti käyttökelpoisten 15-deoksispergualiinianalogien valmistamiseksi sekä menetelmässä käytettävät välituotteet

Country Status (24)

Country Link
US (1) US5476870A (fi)
EP (1) EP0600762B1 (fi)
JP (1) JP2945261B2 (fi)
KR (1) KR100187328B1 (fi)
CN (1) CN1045431C (fi)
AT (1) ATE140215T1 (fi)
AU (1) AU664124B2 (fi)
CA (1) CA2110437C (fi)
CZ (1) CZ284958B6 (fi)
DE (1) DE69303583T2 (fi)
DK (1) DK0600762T3 (fi)
ES (1) ES2092263T3 (fi)
FI (1) FI112211B (fi)
FR (1) FR2698628B1 (fi)
GR (1) GR3021269T3 (fi)
HK (1) HK1000467A1 (fi)
HU (1) HU218908B (fi)
NO (1) NO180483C (fi)
NZ (1) NZ250330A (fi)
RU (1) RU2114823C1 (fi)
SK (1) SK280286B6 (fi)
TW (1) TW311132B (fi)
UA (1) UA39920C2 (fi)
ZA (1) ZA938821B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69600780T2 (de) * 1995-02-10 1999-05-27 Fournier Ind & Sante 15-deoxyspergualin-analoge verbindungen, ihre verwendung als therapeutika und verfahren zu ihrer herstellung
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) * 1997-07-03 1999-01-07 Niels Franke Niedrigdosierte 15-Desoxyspergualin-Präparate
ES2170042T3 (es) * 1998-08-28 2004-10-01 Gryphon Therapeutics, Inc. Procedimiento para la preparacion de cadenas de poliamida de longitud precisa y sus conjugados con proteinas.
DE19923961A1 (de) * 1999-05-25 2000-11-30 Euro Nippon Kayaku Gmbh Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
AU2005237764B2 (en) 2004-05-05 2011-11-24 Silence Therapeutics Gmbh Lipids, lipid complexes and use thereof
EP2992902A1 (en) 2004-12-27 2016-03-09 Silence Therapeutics GmbH Lipid complexes coated with peg and their uses
EP2269980A4 (de) 2008-12-24 2011-05-18 Vertex Closed Joint Stock Company Creatinamide, verfahren zu ihrer herstellung und wirkstoff zur ausführung einer neuroprotektiven aktion
RU2428414C2 (ru) 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
CA2806942C (en) * 2010-07-29 2019-06-25 Jocelyne Annat Compounds for the treatment/prevention of ocular inflammatory diseases
FR2963238B1 (fr) * 2010-07-29 2012-12-28 Fournier Lab Sa Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
KR101695730B1 (ko) 2015-03-10 2017-01-12 하경훈 마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) * 2016-04-26 2019-06-14 Temisis Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5942356A (ja) * 1982-09-02 1984-03-08 Microbial Chem Res Found スパガリン関連化合物およびその製造法
ATE64378T1 (de) * 1986-04-04 1991-06-15 Microbial Chem Res Found Spergualinaehnliche verbindungen und ihr herstellungsverfahren.
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions

Also Published As

Publication number Publication date
CZ262293A3 (en) 1994-06-15
FR2698628B1 (fr) 1995-02-17
FI112211B (fi) 2003-11-14
EP0600762B1 (fr) 1996-07-10
FR2698628A1 (fr) 1994-06-03
JPH06293728A (ja) 1994-10-21
ZA938821B (en) 1994-06-30
JP2945261B2 (ja) 1999-09-06
KR100187328B1 (ko) 1999-05-15
DE69303583T2 (de) 1996-11-21
HUT65782A (en) 1994-07-28
CA2110437C (en) 1999-04-13
DE69303583D1 (de) 1996-08-14
NZ250330A (en) 1995-06-27
KR940014435A (ko) 1994-07-18
NO934338L (no) 1994-06-03
US5476870A (en) 1995-12-19
HU9303406D0 (en) 1994-03-28
AU664124B2 (en) 1995-11-02
RU2114823C1 (ru) 1998-07-10
CZ284958B6 (cs) 1999-04-14
AU5188393A (en) 1994-06-16
FI935318A0 (fi) 1993-11-29
ATE140215T1 (de) 1996-07-15
GR3021269T3 (en) 1997-01-31
SK280286B6 (sk) 1999-11-08
NO934338D0 (no) 1993-11-30
CN1095709A (zh) 1994-11-30
TW311132B (fi) 1997-07-21
NO180483B (no) 1997-01-20
NO180483C (no) 1997-04-30
CA2110437A1 (en) 1994-06-03
EP0600762A1 (fr) 1994-06-08
CN1045431C (zh) 1999-10-06
HK1000467A1 (en) 1998-03-27
SK135793A3 (en) 1994-06-08
ES2092263T3 (es) 1996-11-16
UA39920C2 (uk) 2001-07-16
DK0600762T3 (da) 1996-11-11
HU218908B (hu) 2000-12-28

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MA Patent expired