ATE140215T1 - 15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr - Google Patents

15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr

Info

Publication number: ATE140215T1
Authority: AT; Austria
Prior art keywords: deoxyspergualin; therapeutics; suppressing; production; immune defense
Prior art date: 1992-12-02

Application number

AT93402795T

Other languages

English (en)

Inventor

Patrice Renaut

Luc Lebreton

Patrick Dutartre

Philippe Derrepas

Soth Samreth

Original Assignee

Fournier Ind & Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-02

Filing date

1993-11-17

Publication date

1996-07-15

1993-11-17 Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante

1996-07-15 Application granted granted Critical

1996-07-15 Publication of ATE140215T1 publication Critical patent/ATE140215T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Transplantation (AREA)
Tropical Medicine & Parasitology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Plant Substances (AREA)
Peptides Or Proteins (AREA)
Curing Cements, Concrete, And Artificial Stone (AREA)
Soil Conditioners And Soil-Stabilizing Materials (AREA)

AT93402795T 1992-12-02 1993-11-17 15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr ATE140215T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9214517A FR2698628B1 (fr)	1992-12-02	1992-12-02	Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.

Publications (1)

Publication Number	Publication Date
ATE140215T1 true ATE140215T1 (de)	1996-07-15

Family

ID=9436147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93402795T ATE140215T1 (de)	1992-12-02	1993-11-17	15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr

Country Status (24)

Country	Link
US (1)	US5476870A (de)
EP (1)	EP0600762B1 (de)
JP (1)	JP2945261B2 (de)
KR (1)	KR100187328B1 (de)
CN (1)	CN1045431C (de)
AT (1)	ATE140215T1 (de)
AU (1)	AU664124B2 (de)
CA (1)	CA2110437C (de)
CZ (1)	CZ284958B6 (de)
DE (1)	DE69303583T2 (de)
DK (1)	DK0600762T3 (de)
ES (1)	ES2092263T3 (de)
FI (1)	FI112211B (de)
FR (1)	FR2698628B1 (de)
GR (1)	GR3021269T3 (de)
HK (1)	HK1000467A1 (de)
HU (1)	HU218908B (de)
NO (1)	NO180483C (de)
NZ (1)	NZ250330A (de)
RU (1)	RU2114823C1 (de)
SK (1)	SK280286B6 (de)
TW (1)	TW311132B (de)
UA (1)	UA39920C2 (de)
ZA (1)	ZA938821B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1996024579A1 (fr) *	1995-02-10	1996-08-15	Fournier Industrie Et Sante	Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation
FR2734263B1 (fr) *	1995-05-17	1997-06-20	Fournier Ind & Sante	Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DE19728436A1 (de) *	1997-07-03	1999-01-07	Niels Franke	Niedrigdosierte 15-Desoxyspergualin-Präparate
AU764144B2 (en) *	1998-08-28	2003-08-14	Gryphon Therapeutics, Inc.	Polyamide chains of precise length, methods to manufacture them and their conjugates
DE19923961A1 (de) *	1999-05-25	2000-11-30	Euro Nippon Kayaku Gmbh	Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen
WO2005105152A2 (en)	2004-05-05	2005-11-10	Atugen Ag	Lipids, lipid complexes and use thereof
CN101287497B (zh)	2004-12-27	2013-03-06	赛伦斯治疗公司	涂层脂质复合体和它们的用途
EP2269980A4 (de)	2008-12-24	2011-05-18	Vertex Closed Joint Stock Company	Creatinamide, verfahren zu ihrer herstellung und wirkstoff zur ausführung einer neuroprotektiven aktion
RU2428414C2 (ru)	2009-11-03	2011-09-10	Закрытое Акционерное Общество "Вертекс"	Способ получения амидов креатина
FR2963238B1 (fr) *	2010-07-29	2012-12-28	Fournier Lab Sa	Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
CA2806942C (en) *	2010-07-29	2019-06-25	Jocelyne Annat	Compounds for the treatment/prevention of ocular inflammatory diseases
KR101695730B1 (ko)	2015-03-10	2017-01-12	하경훈	마늘꼭지 절단기의 절단장치
FR3050455B1 (fr) *	2016-04-26	2019-06-14	Temisis	Derives amides des acides polycafeoylquiniques, procede de preparation et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5942356A (ja) *	1982-09-02	1984-03-08	Microbial Chem Res Found	スパガリン関連化合物およびその製造法
ES2039213T3 (es) *	1986-04-04	1993-09-16	Microbial Chemistry Research Foundation	Procedimiento para producir nuevos compuestos relacionados con espergualina.
US5061787A (en) *	1988-06-24	1991-10-29	Nippon Kayaku Kabushiki Kaisha	Novel spergualin-related compounds and compositions

1992
- 1992-12-02 FR FR9214517A patent/FR2698628B1/fr not_active Expired - Fee Related
1993
- 1993-11-17 AT AT93402795T patent/ATE140215T1/de not_active IP Right Cessation
- 1993-11-17 DE DE69303583T patent/DE69303583T2/de not_active Expired - Fee Related
- 1993-11-17 ES ES93402795T patent/ES2092263T3/es not_active Expired - Lifetime
- 1993-11-17 EP EP93402795A patent/EP0600762B1/de not_active Expired - Lifetime
- 1993-11-17 DK DK93402795.4T patent/DK0600762T3/da active
- 1993-11-19 TW TW082109707A patent/TW311132B/zh active
- 1993-11-24 AU AU51883/93A patent/AU664124B2/en not_active Ceased
- 1993-11-25 ZA ZA938821A patent/ZA938821B/xx unknown
- 1993-11-29 FI FI935318A patent/FI112211B/fi not_active IP Right Cessation
- 1993-11-30 NO NO934338A patent/NO180483C/no not_active IP Right Cessation
- 1993-11-30 KR KR1019930025761A patent/KR100187328B1/ko not_active IP Right Cessation
- 1993-11-30 NZ NZ250330A patent/NZ250330A/en unknown
- 1993-12-01 CA CA002110437A patent/CA2110437C/en not_active Expired - Fee Related
- 1993-12-01 UA UA93003726A patent/UA39920C2/uk unknown
- 1993-12-01 HU HU9303406A patent/HU218908B/hu not_active IP Right Cessation
- 1993-12-01 RU RU93053038A patent/RU2114823C1/ru not_active IP Right Cessation
- 1993-12-02 CZ CZ932622A patent/CZ284958B6/cs not_active IP Right Cessation
- 1993-12-02 CN CN93121647A patent/CN1045431C/zh not_active Expired - Fee Related
- 1993-12-02 US US08/161,773 patent/US5476870A/en not_active Expired - Fee Related
- 1993-12-02 SK SK1357-93A patent/SK280286B6/sk unknown
- 1993-12-02 JP JP5342673A patent/JP2945261B2/ja not_active Expired - Fee Related
1996
- 1996-10-04 GR GR960402621T patent/GR3021269T3/el unknown
1997
- 1997-11-04 HK HK97102083A patent/HK1000467A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU664124B2 (en)	1995-11-02
HU218908B (hu)	2000-12-28
NO180483C (no)	1997-04-30
KR100187328B1 (ko)	1999-05-15
ES2092263T3 (es)	1996-11-16
NO934338L (no)	1994-06-03
HK1000467A1 (en)	1998-03-27
DE69303583D1 (de)	1996-08-14
US5476870A (en)	1995-12-19
CN1045431C (zh)	1999-10-06
ZA938821B (en)	1994-06-30
NO180483B (no)	1997-01-20
GR3021269T3 (en)	1997-01-31
EP0600762A1 (de)	1994-06-08
JPH06293728A (ja)	1994-10-21
NO934338D0 (no)	1993-11-30
FI935318A0 (fi)	1993-11-29
FI112211B (fi)	2003-11-14
FI935318A (fi)	1994-06-03
CZ284958B6 (cs)	1999-04-14
CA2110437A1 (en)	1994-06-03
KR940014435A (ko)	1994-07-18
CZ262293A3 (en)	1994-06-15
DE69303583T2 (de)	1996-11-21
SK280286B6 (sk)	1999-11-08
RU2114823C1 (ru)	1998-07-10
SK135793A3 (en)	1994-06-08
JP2945261B2 (ja)	1999-09-06
NZ250330A (en)	1995-06-27
UA39920C2 (uk)	2001-07-16
DK0600762T3 (da)	1996-11-11
EP0600762B1 (de)	1996-07-10
CN1095709A (zh)	1994-11-30
FR2698628A1 (fr)	1994-06-03
CA2110437C (en)	1999-04-13
FR2698628B1 (fr)	1995-02-17
AU5188393A (en)	1994-06-16
HUT65782A (en)	1994-07-28
TW311132B (de)	1997-07-21
HU9303406D0 (en)	1994-03-28

Legal Events

Date	Code	Title	Description
1996-12-15	UEP	Publication of translation of european patent specification
2006-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE140215T1 (de)	1996-07-15	15-deoxyspergualin analoge verbindungen, verfahren zu ihrer herstellung und ihre verwendung als therapeutika zur unterdrückung der immunabwehr
ATE225348T1 (de)	2002-10-15	Substituierte azaindolylidenderivate und verfahren zu ihrer herstellung
ATE181074T1 (de)	1999-06-15	Vinylen-azaindolderivate und verfahren zu ihrer herstellung
GR861127B (en)	1986-08-26	Meth-acryl acid esters and their use
DE59209965D1 (de)	2002-10-17	Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung
ATE132487T1 (de)	1996-01-15	Verfahren zur herstellung von substituierten piperidinen
ATE90676T1 (de)	1993-07-15	Dioxyalkylenaryl-dihydropyridine zwischenprodukte zu ihrer herstellung, verfahren zu ihrer herstellung und ihre verwendung.
ATE3771T1 (de)	1983-06-15	Dimethylphosphinyl-alkanphosphonsaeuren, ein verfahren zu ihrer herstellung und ihre verwendung als gipsabbindeverzoegerer.
ATE134623T1 (de)	1996-03-15	Salicyl(thio)etherderivate, verfahren und zwischenprodukte zu ihrer herstellung
DE69208208D1 (de)	1996-03-21	Verfahren zur herstellung von gereinigtem naphthalendikarbonsäuredimethylester
ATE133938T1 (de)	1996-02-15	Indan-1,3-dion und indan-1,2,3-trionderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
ATE111734T1 (de)	1994-10-15	Verfahren zur herstellung von direktkomprimierten, cephalosporansäure derivate enthaltendentabletten.
DE59206545D1 (de)	1996-07-18	Modifizierte Huminate, Verfahren zu ihrer Herstellung und Verwendung
DE3770037D1 (de)	1991-06-20	Dissymmetrische 1,4-dihydropyridin-3,5-dicarbonsaeure-derivate, verfahren zur herstellung und verwendung in therapeutik.
DK0617027T3 (da)	2000-10-09	N-benzylpiperazinforbindelser, fremgangsmåde til fremstilling heraf og sammensætninger indeholdende forbindelserne
ATE157655T1 (de)	1997-09-15	Verfahren zur herstellung von gegebenfalls 2- substituierten 5-chlorimidazolen
ATE158576T1 (de)	1997-10-15	Alpha-aryl-alpha-hydroxy-beta- imidazolinylpropionsäureamide
DE69405507T2 (de)	1998-02-12	Zwischenprodukte zur Herstellung von Vitamin A und von Carotenoiden und Verfahren zu deren Herstellung
DK0656379T3 (da)	1999-10-25	Fremgangsmåde til fremstilling af polyurethangenstande fra uretonimin-baserede sammensætninger
ATE23528T1 (de)	1986-11-15	+/- 2-((3,4-methylenedioxy)phenethyl)-5-((3carboxamido-4-hydroxy)-alpha-hydroxybenzyl)pyrrolidine, pharmazeutische zusammenstellungen die sie enthalten, verfahren zur herstellung und deren zwischenprodukte.
ATE169961T1 (de)	1998-09-15	Verfahren zur herstellung von 2,5- dihydroxyphenylessigsäure
DE3868948D1 (de)	1992-04-16	4,4-dimethyltetrahydropyr-2-on-derivate, verfahren zu ihrer herstellung und ihre verwendung zur synthese von pyretrinverbindungen.