FI934298A - Kristallin tiagabine-hydrokloridmonohydrat, dess framstaellning och dess anvaendning - Google Patents
Kristallin tiagabine-hydrokloridmonohydrat, dess framstaellning och dess anvaendning Download PDFInfo
- Publication number
- FI934298A FI934298A FI934298A FI934298A FI934298A FI 934298 A FI934298 A FI 934298A FI 934298 A FI934298 A FI 934298A FI 934298 A FI934298 A FI 934298A FI 934298 A FI934298 A FI 934298A
- Authority
- FI
- Finland
- Prior art keywords
- dess
- crystal
- hydrochloride monohydrate
- anvaendning
- tiagabine hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Photoreceptors In Electrophotography (AREA)
- Transceivers (AREA)
- Mobile Radio Communication Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK91582A DK58291D0 (da) | 1991-04-02 | 1991-04-02 | Krystalinsk stof og dets fremstilling |
DK58291 | 1991-04-02 | ||
PCT/DK1992/000093 WO1992017473A1 (en) | 1991-04-02 | 1992-03-23 | Crystalline tiagabine hydrochloride monohydrate, its preparation and use |
DK9200093 | 1992-03-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI934298A true FI934298A (fi) | 1993-09-30 |
FI934298A0 FI934298A0 (fi) | 1993-09-30 |
FI110096B FI110096B (fi) | 2002-11-29 |
Family
ID=8095193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI934298A FI110096B (fi) | 1991-04-02 | 1993-09-30 | Menetelmä terapeuttisesti käyttökelpoisen kiteisen Tiagabine-hydrokloridimonohydraatin valmistamiseksi |
Country Status (15)
Country | Link |
---|---|
US (1) | US5354760A (fi) |
EP (1) | EP0579681B1 (fi) |
AT (1) | ATE180781T1 (fi) |
AU (1) | AU661483B2 (fi) |
CA (1) | CA2107223C (fi) |
DE (1) | DE69229339T2 (fi) |
DK (2) | DK58291D0 (fi) |
ES (1) | ES2134801T3 (fi) |
FI (1) | FI110096B (fi) |
GR (1) | GR3030919T3 (fi) |
IL (1) | IL101358A (fi) |
NO (1) | NO304113B1 (fi) |
NZ (1) | NZ242191A (fi) |
WO (1) | WO1992017473A1 (fi) |
ZA (1) | ZA922297B (fi) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750140A (en) * | 1994-05-20 | 1998-05-12 | Novo Nordisk A/S | Transdermal delivery of tiagabine |
PL183678B1 (pl) * | 1995-05-05 | 2002-06-28 | Novo Nordisk As | Środek farmaceutyczny zawierający tiagabinę i sposób wytwarzania środka farmaceutycznego zawierającego tiagabinę |
DE19525598C2 (de) * | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
AU736514B2 (en) * | 1995-07-13 | 2001-07-26 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Non-allosteric gabaa agonists for treating sleep disorders |
UA52661C2 (uk) * | 1996-06-14 | 2003-01-15 | Ново Нордіск А/С | Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти |
US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
IE970588A1 (en) | 1997-08-01 | 2000-08-23 | Elan Corp Plc | Controlled release pharmaceutical compositions containing tiagabine |
FR2771292B1 (fr) * | 1997-11-21 | 2000-02-18 | Ethypharm Lab Prod Ethiques | Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques |
US6410520B2 (en) | 2000-02-01 | 2002-06-25 | The Procter & Gamble Company | Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate |
US6562974B2 (en) | 2000-02-01 | 2003-05-13 | The Procter & Gamble Company | Process for making geminal bisphosphonates |
EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
CN1314684C (zh) * | 2003-12-24 | 2007-05-09 | 中国科学院上海有机化学研究所 | 噻加宾及其消旋体和s-构型的合成方法及其无定形粉末的制法 |
WO2005122698A2 (en) * | 2003-12-24 | 2005-12-29 | Sun Pharmaceutical Industries Limited | Novel stable polymorphic forms of tiagabine hydrochloride |
WO2005092886A1 (en) * | 2004-03-29 | 2005-10-06 | Ranbaxy Laboratories Limited | Process for the preparation of amorphous form of tiagabine |
US20080269495A1 (en) * | 2004-08-04 | 2008-10-30 | Prosenjit Bose | Process for Preparation of Piperidine Carboxylic Acid |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
US20080064727A1 (en) * | 2006-08-18 | 2008-03-13 | Cephalon, Inc. | Crystalline forms of tiagabine hydrochloride |
US20080051435A1 (en) * | 2006-08-18 | 2008-02-28 | Cephalon, Inc. | Crystalline and amorphous forms of tiagabine |
CN101857591B (zh) * | 2009-04-09 | 2013-06-05 | 北京京卫燕康药物研究所有限公司 | 盐酸噻加宾晶型及其制备方法 |
CN103554093B (zh) * | 2013-11-12 | 2015-10-21 | 四川科瑞德凯华制药有限公司 | 噻加宾乙酯盐酸盐及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK288385D0 (da) * | 1985-06-26 | 1985-06-26 | Novo Industri As | Aminosyrederivater |
ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
US4910312A (en) * | 1985-11-08 | 1990-03-20 | Warner-Lambert Company | Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof |
-
1991
- 1991-04-02 DK DK91582A patent/DK58291D0/da not_active Application Discontinuation
-
1992
- 1992-03-23 AU AU16415/92A patent/AU661483B2/en not_active Expired
- 1992-03-23 CA CA002107223A patent/CA2107223C/en not_active Expired - Lifetime
- 1992-03-23 DE DE69229339T patent/DE69229339T2/de not_active Expired - Lifetime
- 1992-03-23 WO PCT/DK1992/000093 patent/WO1992017473A1/en active IP Right Grant
- 1992-03-23 AT AT92908325T patent/ATE180781T1/de active
- 1992-03-23 EP EP92908325A patent/EP0579681B1/en not_active Expired - Lifetime
- 1992-03-23 ES ES92908325T patent/ES2134801T3/es not_active Expired - Lifetime
- 1992-03-23 DK DK92908325T patent/DK0579681T3/da active
- 1992-03-24 US US07/857,038 patent/US5354760A/en not_active Expired - Lifetime
- 1992-03-24 IL IL10135892A patent/IL101358A/en not_active IP Right Cessation
- 1992-03-30 ZA ZA922297A patent/ZA922297B/xx unknown
- 1992-04-01 NZ NZ24219192A patent/NZ242191A/en not_active IP Right Cessation
-
1993
- 1993-09-30 FI FI934298A patent/FI110096B/fi not_active IP Right Cessation
- 1993-10-01 NO NO933524A patent/NO304113B1/no not_active IP Right Cessation
-
1999
- 1999-08-04 GR GR990402003T patent/GR3030919T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1992017473A1 (en) | 1992-10-15 |
ATE180781T1 (de) | 1999-06-15 |
GR3030919T3 (en) | 1999-11-30 |
CA2107223C (en) | 2005-02-15 |
NO304113B1 (no) | 1998-10-26 |
NO933524L (no) | 1993-10-01 |
NZ242191A (en) | 1994-07-26 |
IL101358A (en) | 1996-08-04 |
DE69229339T2 (de) | 1999-12-30 |
AU1641592A (en) | 1992-11-02 |
ES2134801T3 (es) | 1999-10-16 |
US5354760A (en) | 1994-10-11 |
JPH06506209A (ja) | 1994-07-14 |
EP0579681B1 (en) | 1999-06-02 |
ZA922297B (en) | 1992-12-30 |
EP0579681A1 (en) | 1994-01-26 |
AU661483B2 (en) | 1995-07-27 |
DK58291D0 (da) | 1991-04-02 |
FI110096B (fi) | 2002-11-29 |
IL101358A0 (en) | 1992-11-15 |
DK0579681T3 (da) | 1999-11-15 |
FI934298A0 (fi) | 1993-09-30 |
DE69229339D1 (de) | 1999-07-08 |
NO933524D0 (no) | 1993-10-01 |
CA2107223A1 (en) | 1992-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Patent expired |