FI884461A0 - Menetelmä trans-1,1,2-trifenyylibut-1-eenijohdannaisten valmistamiseksi - Google Patents

Menetelmä trans-1,1,2-trifenyylibut-1-eenijohdannaisten valmistamiseksi

Info

Publication number: FI884461A0
Authority: FI; Finland
Prior art keywords: trans; triphenylbut; preparation; ene derivatives; formula
Prior art date: 1987-10-29

Application number

FI884461A

Other languages

English (en)

Swedish (sv)

Other versions

FI884461A (fi

FI94625B (fi

FI94625C (fi

Inventor

Axel Woschina

Helmut Grill

Original Assignee

Klinge Co Chem Pharm Fab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-29

Filing date

1988-09-28

Publication date

1988-09-28

1988-09-28 Application filed by Klinge Co Chem Pharm Fab filed Critical Klinge Co Chem Pharm Fab

1988-09-28 Publication of FI884461A0 publication Critical patent/FI884461A0/fi

1989-04-30 Publication of FI884461A publication Critical patent/FI884461A/fi

1995-06-30 Publication of FI94625B publication Critical patent/FI94625B/fi

1995-10-10 Application granted granted Critical

1995-10-10 Publication of FI94625C publication Critical patent/FI94625C/fi

Links

VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
230000018044 dehydration Effects 0.000 abstract 1
238000006297 dehydration reaction Methods 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000001117 sulphuric acid Substances 0.000 abstract 1
235000011149 sulphuric acid Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Liquid Crystal Substances (AREA)

FI884461A 1987-10-29 1988-09-28 Menetelmä trans-1,1,2-trifenyylibut-1-eenijohdannaisten valmistamiseksi FI94625C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19873736682 DE3736682A1 (de)	1987-10-29	1987-10-29	Verfahren zur herstellung von trans-1,1,2-triphenyl-but-1-en-derivaten
DE3736682		1987-10-29

Publications (4)

Publication Number	Publication Date
FI884461A0 true FI884461A0 (fi)	1988-09-28
FI884461A FI884461A (fi)	1989-04-30
FI94625B FI94625B (fi)	1995-06-30
FI94625C FI94625C (fi)	1995-10-10

Family

ID=6339363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI884461A FI94625C (fi)	1987-10-29	1988-09-28	Menetelmä trans-1,1,2-trifenyylibut-1-eenijohdannaisten valmistamiseksi

Country Status (10)

Country	Link
US (1)	US4960937A (fi)
EP (1)	EP0313799B1 (fi)
AT (1)	ATE85605T1 (fi)
DE (2)	DE3736682A1 (fi)
DK (1)	DK170300B1 (fi)
ES (1)	ES2038263T3 (fi)
FI (1)	FI94625C (fi)
GR (1)	GR3007027T3 (fi)
HU (1)	HU202824B (fi)
NO (1)	NO169120C (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR0169186B1 (ko) *	1993-10-25	1999-03-20	고바야시 유끼오	트리페닐에틸렌 화합물의 z이성체 산부가염의 제조방법
JPH09507240A (ja) *	1994-01-03	1997-07-22	クリンゲ・ファルマ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	Ｅ−１−［４’−（２−ジメチルアミノエトキシ）−フェニル］−１−（３’−ヒドロキシフェニル）−２−フェニル−１−ブテンの製造方法
US5681835A (en) *	1994-04-25	1997-10-28	Glaxo Wellcome Inc.	Non-steroidal ligands for the estrogen receptor
AU725286B2 (en)	1996-01-20	2000-10-12	Bradford University	Tamoxifen and analogues thereof
GB9715479D0 (en) *	1997-07-23	1997-10-01	Univ Bradford	Tamoxifen and analogues thereof
CN1275911A (zh)	1997-08-15	2000-12-06	杜克大学	一种预防或治疗***依赖性疾病及失调的方法
CN114133334B (zh) *	2021-11-09	2024-07-19	北京京丰制药(山东)有限公司	枸橼酸他莫昔芬的工业化制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1013907A (en) *	1962-09-13	1965-12-22	Ici Ltd	Alkene derivatives
BE637389A (fi) *	1962-09-13
DE3046719C2 (de) *	1980-12-11	1983-02-17	Klinge Pharma GmbH, 8000 München	1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
EP0127128B1 (en) *	1983-05-24	1987-02-25	Bristol-Myers Company	Process for the conversion of the e isomer of 1,2-diphenyl-1-(4-(2-dimethylaminoethoxy)-phenyl)-1-butene to tamoxifen hcl
DE3561012D1 (en) *	1984-06-12	1987-12-23	Nat Res Dev	Preparation of tamoxifen
CN1013859B (zh) *	1986-11-21	1991-09-11	中国人民解放军防化研究院第四所	枸橼酸三苯氧胺合成方法的改进

1987
- 1987-10-29 DE DE19873736682 patent/DE3736682A1/de not_active Withdrawn
1988
- 1988-09-19 EP EP88115306A patent/EP0313799B1/de not_active Expired - Lifetime
- 1988-09-19 ES ES198888115306T patent/ES2038263T3/es not_active Expired - Lifetime
- 1988-09-19 AT AT88115306T patent/ATE85605T1/de not_active IP Right Cessation
- 1988-09-19 DE DE8888115306T patent/DE3878394D1/de not_active Expired - Fee Related
- 1988-09-28 FI FI884461A patent/FI94625C/fi not_active IP Right Cessation
- 1988-10-27 US US07/263,209 patent/US4960937A/en not_active Expired - Fee Related
- 1988-10-27 NO NO884800A patent/NO169120C/no not_active IP Right Cessation
- 1988-10-28 HU HU885630A patent/HU202824B/hu not_active IP Right Cessation
- 1988-10-28 DK DK604288A patent/DK170300B1/da not_active IP Right Cessation
1993
- 1993-02-11 GR GR920402546T patent/GR3007027T3/el unknown

Also Published As

Publication number	Publication date
NO169120C (no)	1992-05-13
NO884800L (no)	1989-05-02
DK604288A (da)	1989-04-30
DK604288D0 (da)	1988-10-28
US4960937A (en)	1990-10-02
FI884461A (fi)	1989-04-30
DK170300B1 (da)	1995-07-31
EP0313799B1 (de)	1993-02-10
GR3007027T3 (fi)	1993-07-30
FI94625B (fi)	1995-06-30
DE3878394D1 (de)	1993-03-25
EP0313799A3 (en)	1990-05-30
ES2038263T3 (es)	1993-07-16
NO884800D0 (no)	1988-10-27
HUT51592A (en)	1990-05-28
HU202824B (en)	1991-04-29
EP0313799A2 (de)	1989-05-03
DE3736682A1 (de)	1989-05-11
NO169120B (no)	1992-02-03
FI94625C (fi)	1995-10-10
ATE85605T1 (de)	1993-02-15

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Legal Events

Date	Code	Title	Description
1995-06-01	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: KLINGE PHARMA GMBH