DK604288D0 - Fremgangsmaade til fremstilling af trans-1,,1,2-triphenyl-but-1-en-derivater - Google Patents

Fremgangsmaade til fremstilling af trans-1,,1,2-triphenyl-but-1-en-derivater

Info

Publication number: DK604288D0
Authority: DK; Denmark
Prior art keywords: triphenyl; derivatives; preparing trans; trans; formula
Prior art date: 1987-10-29

Application number

DK604288A

Other languages

English (en)

Other versions

DK604288A (da

DK170300B1 (da

Inventor

Axel Woschina

Helmut Grill

Original Assignee

Klinge Co Chem Pharm Fab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-29

Filing date

1988-10-28

Publication date

1988-10-28

1988-10-28 Application filed by Klinge Co Chem Pharm Fab filed Critical Klinge Co Chem Pharm Fab

1988-10-28 Publication of DK604288D0 publication Critical patent/DK604288D0/da

1989-04-30 Publication of DK604288A publication Critical patent/DK604288A/da

1995-07-31 Application granted granted Critical

1995-07-31 Publication of DK170300B1 publication Critical patent/DK170300B1/da

Links

VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
230000018044 dehydration Effects 0.000 abstract 1
238000006297 dehydration reaction Methods 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000001117 sulphuric acid Substances 0.000 abstract 1
235000011149 sulphuric acid Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Liquid Crystal Substances (AREA)

DK604288A 1987-10-29 1988-10-28 Fremgangsmåde til fremstilling af trans-1,1,2-tri phenyl-but-1-en-derivater DK170300B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19873736682 DE3736682A1 (de)	1987-10-29	1987-10-29	Verfahren zur herstellung von trans-1,1,2-triphenyl-but-1-en-derivaten
DE3736682		1987-10-29

Publications (3)

Publication Number	Publication Date
DK604288D0 true DK604288D0 (da)	1988-10-28
DK604288A DK604288A (da)	1989-04-30
DK170300B1 DK170300B1 (da)	1995-07-31

Family

ID=6339363

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK604288A DK170300B1 (da)	1987-10-29	1988-10-28	Fremgangsmåde til fremstilling af trans-1,1,2-tri phenyl-but-1-en-derivater

Country Status (10)

Country	Link
US (1)	US4960937A (da)
EP (1)	EP0313799B1 (da)
AT (1)	ATE85605T1 (da)
DE (2)	DE3736682A1 (da)
DK (1)	DK170300B1 (da)
ES (1)	ES2038263T3 (da)
FI (1)	FI94625C (da)
GR (1)	GR3007027T3 (da)
HU (1)	HU202824B (da)
NO (1)	NO169120C (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0677507B1 (en) *	1993-10-25	1998-04-08	Taiho Pharmaceutical Company Limited	Process for producing acid-addition salt of z-isomer of triphenylethylene compound
JPH09507240A (ja) *	1994-01-03	1997-07-22	クリンゲ・ファルマ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	Ｅ−１−［４’−（２−ジメチルアミノエトキシ）−フェニル］−１−（３’−ヒドロキシフェニル）−２−フェニル−１−ブテンの製造方法
US5681835A (en) *	1994-04-25	1997-10-28	Glaxo Wellcome Inc.	Non-steroidal ligands for the estrogen receptor
HUP9900951A3 (en)	1996-01-20	2000-02-28	Bradford University Bradford	Process for producing tamoxifen and analogues thereof
GB9715479D0 (en) *	1997-07-23	1997-10-01	Univ Bradford	Tamoxifen and analogues thereof
AU757206B2 (en)	1997-08-15	2003-02-06	Duke University	A method of preventing or treating estrogen-dependent diseases and disorders
CN114133334B (zh) *	2021-11-09	2024-07-19	北京京丰制药(山东)有限公司	枸橼酸他莫昔芬的工业化制备工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1013907A (en) *	1962-09-13	1965-12-22	Ici Ltd	Alkene derivatives
BE637389A (da) *	1962-09-13
DE3046719C2 (de) *	1980-12-11	1983-02-17	Klinge Pharma GmbH, 8000 München	1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
ATE25515T1 (de) *	1983-05-24	1987-03-15	Bristol Myers Co	Verfahren zur umwandlung von 1,2-diphenyl-1-(4-(2-dimethylamino-ethoxy)-phen l>-1-buten-e-isomeren zu tamoxifen-hydrochlorid.
EP0168175B1 (en) *	1984-06-12	1987-11-19	National Research Development Corporation	Preparation of tamoxifen
CN1013859B (zh) *	1986-11-21	1991-09-11	中国人民解放军防化研究院第四所	枸橼酸三苯氧胺合成方法的改进

1987
- 1987-10-29 DE DE19873736682 patent/DE3736682A1/de not_active Withdrawn
1988
- 1988-09-19 AT AT88115306T patent/ATE85605T1/de not_active IP Right Cessation
- 1988-09-19 EP EP88115306A patent/EP0313799B1/de not_active Expired - Lifetime
- 1988-09-19 DE DE8888115306T patent/DE3878394D1/de not_active Expired - Fee Related
- 1988-09-19 ES ES198888115306T patent/ES2038263T3/es not_active Expired - Lifetime
- 1988-09-28 FI FI884461A patent/FI94625C/fi not_active IP Right Cessation
- 1988-10-27 US US07/263,209 patent/US4960937A/en not_active Expired - Fee Related
- 1988-10-27 NO NO884800A patent/NO169120C/no not_active IP Right Cessation
- 1988-10-28 DK DK604288A patent/DK170300B1/da not_active IP Right Cessation
- 1988-10-28 HU HU885630A patent/HU202824B/hu not_active IP Right Cessation
1993
- 1993-02-11 GR GR920402546T patent/GR3007027T3/el unknown

Also Published As

Publication number	Publication date
DE3878394D1 (de)	1993-03-25
ATE85605T1 (de)	1993-02-15
GR3007027T3 (da)	1993-07-30
FI884461A (fi)	1989-04-30
DK604288A (da)	1989-04-30
NO884800L (no)	1989-05-02
FI94625C (fi)	1995-10-10
NO884800D0 (no)	1988-10-27
EP0313799A2 (de)	1989-05-03
HUT51592A (en)	1990-05-28
FI884461A0 (fi)	1988-09-28
HU202824B (en)	1991-04-29
DE3736682A1 (de)	1989-05-11
NO169120C (no)	1992-05-13
ES2038263T3 (es)	1993-07-16
EP0313799B1 (de)	1993-02-10
EP0313799A3 (en)	1990-05-30
US4960937A (en)	1990-10-02
FI94625B (fi)	1995-06-30
DK170300B1 (da)	1995-07-31
NO169120B (no)	1992-02-03

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Legal Events

Date	Code	Title	Description
1995-07-31	B1	Patent granted (law 1993)
2001-06-11	PBP	Patent lapsed