FI67686C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat Download PDF

Info

Publication number: FI67686C
Authority: FI; Finland
Prior art keywords: formula; dimethyl; compound; phenyl; tumor
Prior art date: 1978-07-03

Application number

FI792080A

Other languages

English (en)

Finnish (fi)

Other versions

FI792080A (fi

FI67686B (fi

Inventor

Jack Mills

Klaus Kurt Schmiegel

Richard Eugene Toomey

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-07-03

Filing date

1979-07-02

Publication date

1985-05-10

1979-07-02 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1980-01-04 Publication of FI792080A publication Critical patent/FI792080A/fi

1985-01-31 Application granted granted Critical

1985-01-31 Publication of FI67686B publication Critical patent/FI67686B/fi

1985-05-10 Publication of FI67686C publication Critical patent/FI67686C/fi

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI792080A 1978-07-03 1979-07-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat FI67686C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US92166878A	1978-07-03	1978-07-03
US92166878		1978-07-03

Publications (3)

Publication Number	Publication Date
FI792080A FI792080A (fi)	1980-01-04
FI67686B FI67686B (fi)	1985-01-31
FI67686C true FI67686C (fi)	1985-05-10

Family

ID=25445786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI792080A FI67686C (fi)	1978-07-03	1979-07-02	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat

Country Status (33)

Country	Link
EP (2)	EP0007206B1 (fr)
JP (1)	JPS559100A (fr)
AR (2)	AR222658A1 (fr)
AT (1)	AT370408B (fr)
AU (1)	AU521744B2 (fr)
BE (1)	BE877392A (fr)
BG (3)	BG40482A3 (fr)
CA (1)	CA1120058A (fr)
CH (1)	CH641759A5 (fr)
CS (2)	CS208661B2 (fr)
DD (1)	DD144763A5 (fr)
DK (1)	DK268579A (fr)
EG (1)	EG14400A (fr)
ES (2)	ES482153A1 (fr)
FI (1)	FI67686C (fr)
FR (1)	FR2430409A1 (fr)
GB (1)	GB2028800B (fr)
GR (1)	GR72546B (fr)
HK (1)	HK44087A (fr)
HU (1)	HU179170B (fr)
IE (1)	IE48436B1 (fr)
IL (1)	IL57670A (fr)
LU (1)	LU81456A1 (fr)
MX (1)	MX6160E (fr)
MY (1)	MY8500596A (fr)
NZ (1)	NZ190859A (fr)
PH (1)	PH15650A (fr)
PL (2)	PL123990B1 (fr)
PT (1)	PT69840A (fr)
RO (2)	RO83053B (fr)
SU (2)	SU965351A3 (fr)
YU (1)	YU154879A (fr)
ZA (1)	ZA793295B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0006735B1 (fr) *	1978-06-28	1983-06-15	Beecham Group Plc	Amines secondaires, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation
NL8105170A (nl) *	1980-12-10	1982-07-01	Thomae Gmbh Dr K	Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen.
EP0068669A1 (fr) *	1981-06-20	1983-01-05	Beecham Group Plc	Phényléthanolamines secondaires, procédés de leur préparation et leur application pharmaceutique
CA1219865A (fr) *	1982-05-14	1987-03-31	Leo Alig	Derives de phenethanolamine d'aziridine
CA1258454A (fr) *	1982-08-10	1989-08-15	Leo Alig	Phenethanolamines
EP0102213A1 (fr) *	1982-08-21	1984-03-07	Beecham Group Plc	Dérivés de l'éthanolamine, compositions pharmaceutiques les contenant et procédés pour leur préparation
US4849453A (en) *	1983-01-31	1989-07-18	Eli Lilly And Company	Growth promotion
PH20912A (en) *	1983-01-31	1987-05-28	Lilly Co Eli	-phenethanolamine derivatives useful for promoting the growth, improving the efficiency of feed utilization and improving the leanless of domesticated animals
US4569801A (en) *	1984-10-15	1986-02-11	Eli Lilly And Company	Alkylsulfonamidophenylalkylamines
JPS62155213A (ja) *	1985-12-20	1987-07-10	イ−ライ・リリ−・アンド・カンパニ−	腫瘍細胞崩壊剤
EG18188A (en) *	1986-05-01	1992-09-30	Pfizer Ltd	Process for preparation anti-arhythmia agents
US5135955A (en) *	1988-04-25	1992-08-04	Eli Lilly And Company	Propanamine derivatives
US5051423A (en) *	1988-07-13	1991-09-24	Schering Ag	Derivatized alkanolamines as cardiovascular agents
US5541197A (en) *	1994-04-26	1996-07-30	Merck & Co., Inc.	Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
US5561142A (en) *	1994-04-26	1996-10-01	Merck & Co., Inc.	Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
CN1073983C (zh) *	1994-10-31	2001-10-31	中国科学院成都有机化学研究所	一种β－拟肾上腺素***型饲料添加剂的合成方法
US7547716B2 (en)	2001-06-08	2009-06-16	Institute Of Medicinal Molecular Design, Inc.	Sulfonamide derivatives
TW200740779A (en)	2005-07-22	2007-11-01	Mitsubishi Pharma Corp	Intermediate compound for synthesizing pharmaceutical agent and production method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL6610530A (fr) *	1966-07-27	1968-01-29
BE757005A (fr) *	1969-10-02	1971-04-02	Bristol Myers Co	Phenethanolamines substituees et procede pour leur preparation
US3801631A (en) *	1972-02-16	1974-04-02	Mead Johnson & Co	2'-hydroxy-5'-(1-hydroxy-2-(2-methyl-1-phenyl-2-propylamino)ethyl)meth-anesulfonanilide and its salts

1979
- 1979-06-26 CA CA000330569A patent/CA1120058A/fr not_active Expired
- 1979-06-26 IL IL57670A patent/IL57670A/xx unknown
- 1979-06-26 DK DK268579A patent/DK268579A/da not_active Application Discontinuation
- 1979-06-27 PH PH22700A patent/PH15650A/en unknown
- 1979-06-27 NZ NZ190859A patent/NZ190859A/en unknown
- 1979-06-27 EG EG386/79A patent/EG14400A/xx active
- 1979-06-28 YU YU01548/79A patent/YU154879A/xx unknown
- 1979-06-28 AU AU48488/79A patent/AU521744B2/en not_active Ceased
- 1979-06-28 PT PT69840A patent/PT69840A/pt unknown
- 1979-06-29 FR FR7916992A patent/FR2430409A1/fr active Granted
- 1979-06-29 HU HU79EI866A patent/HU179170B/hu unknown
- 1979-07-02 GB GB7922953A patent/GB2028800B/en not_active Expired
- 1979-07-02 SU SU792786502A patent/SU965351A3/ru active
- 1979-07-02 BG BG7945920A patent/BG40482A3/xx unknown
- 1979-07-02 CH CH616479A patent/CH641759A5/fr not_active IP Right Cessation
- 1979-07-02 RO RO105066A patent/RO83053B/ro unknown
- 1979-07-02 BG BG7944165A patent/BG40480A3/xx unknown
- 1979-07-02 BG BG7945919A patent/BG40481A3/xx unknown
- 1979-07-02 MX MX798145U patent/MX6160E/es unknown
- 1979-07-02 EP EP79301282A patent/EP0007206B1/fr not_active Expired
- 1979-07-02 GR GR59488A patent/GR72546B/el unknown
- 1979-07-02 CS CS794630A patent/CS208661B2/cs unknown
- 1979-07-02 EP EP81109790A patent/EP0047536B1/fr not_active Expired
- 1979-07-02 FI FI792080A patent/FI67686C/fi not_active IP Right Cessation
- 1979-07-02 RO RO7998011A patent/RO77731A/fr unknown
- 1979-07-02 LU LU81456A patent/LU81456A1/fr unknown
- 1979-07-02 BE BE1/9443A patent/BE877392A/fr not_active IP Right Cessation
- 1979-07-02 JP JP8489479A patent/JPS559100A/ja active Granted
- 1979-07-02 CS CS794630A patent/CS208660B2/cs unknown
- 1979-07-03 AT AT0463979A patent/AT370408B/de not_active IP Right Cessation
- 1979-07-03 PL PL1979222867A patent/PL123990B1/pl unknown
- 1979-07-03 AR AR277165A patent/AR222658A1/es active
- 1979-07-03 DD DD79214071A patent/DD144763A5/de unknown
- 1979-07-03 ES ES482153A patent/ES482153A1/es not_active Expired
- 1979-07-03 ZA ZA793295A patent/ZA793295B/xx unknown
- 1979-07-03 PL PL1979216810A patent/PL119783B1/pl unknown
- 1979-08-08 IE IE1231/79A patent/IE48436B1/en unknown
1980
- 1980-01-18 ES ES487847A patent/ES487847A0/es active Granted
- 1980-09-12 SU SU802977044A patent/SU931102A3/ru active
- 1980-10-06 AR AR282776A patent/AR222727A1/es active
1985
- 1985-12-30 MY MY596/85A patent/MY8500596A/xx unknown
1987
- 1987-06-04 HK HK440/87A patent/HK44087A/xx unknown

Also Published As

Publication number	Publication date
AU4848879A (en)	1980-01-10
GR72546B (fr)	1983-11-17
FR2430409A1 (fr)	1980-02-01
GB2028800A (en)	1980-03-12
BG40481A3 (en)	1986-12-15
BE877392A (fr)	1980-01-02
SU965351A3 (ru)	1982-10-07
RO77731A (fr)	1981-11-24
BG40482A3 (en)	1986-12-15
CH641759A5 (fr)	1984-03-15
ES8101537A1 (es)	1980-12-16
FR2430409B1 (fr)	1981-05-29
EP0047536A2 (fr)	1982-03-17
CA1120058A (fr)	1982-03-16
EP0047536A3 (en)	1982-03-24
DK268579A (da)	1980-01-04
AT370408B (de)	1983-03-25
PL222867A1 (fr)	1981-01-02
FI792080A (fi)	1980-01-04
EG14400A (en)	1983-12-31
JPS636058B2 (fr)	1988-02-08
BG40480A3 (en)	1986-12-15
AU521744B2 (en)	1982-04-29
HK44087A (en)	1987-06-12
ATA463979A (de)	1982-08-15
GB2028800B (en)	1982-11-03
LU81456A1 (fr)	1979-10-30
PL119783B1 (en)	1982-01-30
IE48436B1 (en)	1985-01-23
EP0007206B1 (fr)	1983-02-23
JPS559100A (en)	1980-01-22
EP0047536B1 (fr)	1984-06-27
SU931102A3 (ru)	1982-05-23
DD144763A5 (de)	1980-11-05
FI67686B (fi)	1985-01-31
HU179170B (en)	1982-08-28
AR222658A1 (es)	1981-06-15
RO83053A (fr)	1984-02-21
ZA793295B (en)	1981-02-25
MY8500596A (en)	1985-12-31
IL57670A (en)	1982-11-30
PL123990B1 (en)	1982-12-31
RO83053B (ro)	1984-02-28
NZ190859A (en)	1984-09-28
ES487847A0 (es)	1980-12-16
IL57670A0 (en)	1979-10-31
IE791231L (en)	1980-01-03
EP0007206A1 (fr)	1980-01-23
PL216810A1 (fr)	1980-07-28
ES482153A1 (es)	1980-08-16
AR222727A1 (es)	1981-06-15
PH15650A (en)	1983-03-11
CS208660B2 (en)	1981-09-15
MX6160E (es)	1984-11-29
YU154879A (en)	1983-04-30
CS208661B2 (en)	1981-09-15
PT69840A (en)	1979-07-01

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: ELI LILLY AND COMPANY

Publication	Publication Date	Title
FI67686C (fi)	1985-05-10	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat
JP2656699B2 (ja)	1997-09-24	置換ベンジルアミノキヌクリジン
EP0284621B1 (fr)	1995-01-18	Nouvel agent psychostimulant
JP4685243B2 (ja)	2011-05-18	ピリミド［６，１−ａ］イソキノリン−４−オン誘導体
JP2003515590A (ja)	2003-05-07	癌を処置するためのクルクミンアナログ
US7759361B2 (en)	2010-07-20	Azabicyclooctan-3-one derivatives and use thereof
AU648121B2 (en)	1994-04-14	Synergism of HIV reverse transcriptase inhibitors
WO1994009001A1 (fr)	1994-04-28	Pyrroloquinoline antagoniste de la bradykinine
JPH07503703A (ja)	1995-04-20	（−）−エゼロリン、（−）−ｎ１−ノルエゼロリンおよび（−）−ｎ１−ベンジルノルエゼロリンの置換フェンゼリンおよびフェニルカルバミン酸塩：特異的アセチルコリンエステラーゼ阻害薬としての使用
JPS62111962A (ja)	1987-05-22	３−フエニルチオメチルスチレン誘導体
US6387389B1 (en)	2002-05-14	Sustained-release derivatives of hydroxylated analogs of substituted 1-[2[bis(aryl)methoxy]ethyl]-piperazines and -homopiperazines and their use
US4942163A (en)	1990-07-17	1(2H)-isoquinolinones and 1-isoquinolineamines as cancer chemotherapeutic agents
JPH11506453A (ja)	1999-06-08	水溶性カンプトテシン類似体
CA2196370A1 (fr)	1997-08-01	Derives de l'isoprene
JPH0755923B2 (ja)	1995-06-14	医薬組成物
US4134991A (en)	1979-01-16	Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid
Kam et al.	1984	[(Arylcarbonyl) oxy] propanolamines. 1. Novel. beta.-blockers with ultrashort duration of action
US20020037931A1 (en)	2002-03-28	Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them
US4970214A (en)	1990-11-13	Quinoline substituted oxomethyl or thioxomethyl glycine derivatives and aldose reductase inhibition therewith
EP4310070A1 (fr)	2024-01-24	Utilisation d'un dérivé de trans-amantadine ou d'un sel de celui-ci
TWI254707B (en)	2006-05-11	Benzazepine derivatives as MAO-B inhibitors
GB1590155A (en)	1981-05-28	Cis-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines and pharmaceutical compositions containing them
AU774981B2 (en)	2004-07-15	Thiazolopyrimidines useful as TNFalpha inhibitors
US3457354A (en)	1969-07-22	Treatment of hypertension with 2-hydroxy (or amino) - 4,5 - dihydroxyphenethylamine derivatives
FI67364B (fi)	1984-11-30	Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol