FI65998C - Foerfarande foer framstaellning av nya farmakologiskt aktiva pyrrolyl-pyridazinaminderivat - Google Patents

Foerfarande foer framstaellning av nya farmakologiskt aktiva pyrrolyl-pyridazinaminderivat Download PDF

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Publication number
FI65998C
FI65998C FI792832A FI792832A FI65998C FI 65998 C FI65998 C FI 65998C FI 792832 A FI792832 A FI 792832A FI 792832 A FI792832 A FI 792832A FI 65998 C FI65998 C FI 65998C
Authority
FI
Finland
Prior art keywords
hydrogen
formula
lower alkyl
pyridazine
hydrazino
Prior art date
Application number
FI792832A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI65998B (fi
FI792832A (fi
Inventor
Elvio Bellasio
Nunzio Di Mola
Ambrogio Campi
Emiliana Baldoli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI792832A publication Critical patent/FI792832A/fi
Publication of FI65998B publication Critical patent/FI65998B/fi
Application granted granted Critical
Publication of FI65998C publication Critical patent/FI65998C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
FI792832A 1978-10-02 1979-09-12 Foerfarande foer framstaellning av nya farmakologiskt aktiva pyrrolyl-pyridazinaminderivat FI65998C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7838898 1978-10-02
GB7838898 1978-10-02

Publications (3)

Publication Number Publication Date
FI792832A FI792832A (fi) 1980-04-03
FI65998B FI65998B (fi) 1984-04-30
FI65998C true FI65998C (fi) 1984-08-10

Family

ID=10500040

Family Applications (1)

Application Number Title Priority Date Filing Date
FI792832A FI65998C (fi) 1978-10-02 1979-09-12 Foerfarande foer framstaellning av nya farmakologiskt aktiva pyrrolyl-pyridazinaminderivat

Country Status (15)

Country Link
EP (1) EP0009655B1 (da)
JP (1) JPS5569577A (da)
AT (1) ATE3294T1 (da)
AU (1) AU529482B2 (da)
CA (1) CA1144165A (da)
DE (1) DE2965377D1 (da)
DK (1) DK151803C (da)
ES (1) ES484616A1 (da)
FI (1) FI65998C (da)
GR (1) GR69856B (da)
IE (1) IE49017B1 (da)
IL (1) IL58256A (da)
NO (1) NO151620C (da)
YU (1) YU41886B (da)
ZA (1) ZA794923B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
US5254622A (en) * 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
RU2006105716A (ru) 2003-07-30 2007-09-10 Зинон Фармасьютиклз Инк. (Ca) Производные пиридазина и их применение в качестве терапевтических средств
CN101083994A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其用作硬脂酰CoA去饱和酶抑制剂的用途
CA2580844A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
AR051026A1 (es) 2004-09-20 2006-12-13 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
CN101083993A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途
WO2006034279A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
CA2580856A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
MX2007003319A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
AU2006343359A1 (en) 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168334A (en) * 1967-01-25 1969-10-22 Lepetit Spa New Pharmacologically Active Pyridazines
GB1378102A (en) * 1972-03-14 1974-12-18 Lepetit Spa Antihypertensive compositions
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives
AU477837B2 (en) * 1973-05-30 1974-12-05 I. S. F. Sp. A New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.

Also Published As

Publication number Publication date
IL58256A (en) 1984-02-29
AU5086679A (en) 1980-04-17
DK151803B (da) 1988-01-04
YU41886B (en) 1988-02-29
IL58256A0 (en) 1979-12-30
NO793151L (no) 1980-04-08
EP0009655B1 (en) 1983-05-11
EP0009655A1 (en) 1980-04-16
ES484616A1 (es) 1980-05-16
GR69856B (da) 1982-07-19
FI65998B (fi) 1984-04-30
JPS5569577A (en) 1980-05-26
FI792832A (fi) 1980-04-03
ZA794923B (en) 1980-09-24
IE791866L (en) 1980-04-02
JPH0321553B2 (da) 1991-03-22
CA1144165A (en) 1983-04-05
DE2965377D1 (en) 1983-06-16
AU529482B2 (en) 1983-06-09
YU237479A (en) 1983-02-28
DK400679A (da) 1980-04-03
DK151803C (da) 1988-06-13
ATE3294T1 (de) 1983-05-15
NO151620C (no) 1985-05-08
NO151620B (no) 1985-01-28
IE49017B1 (en) 1985-07-10

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: GRUPPO LEPETIT S.P.A.