DK151803C - Analogifremgangsmaade til fremstilling af n-pyrrolylpyridazinaminderivater eller farmaceutisk acceptable salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af n-pyrrolylpyridazinaminderivater eller farmaceutisk acceptable salte deraf

Info

Publication number
DK151803C
DK151803C DK400679A DK400679A DK151803C DK 151803 C DK151803 C DK 151803C DK 400679 A DK400679 A DK 400679A DK 400679 A DK400679 A DK 400679A DK 151803 C DK151803 C DK 151803C
Authority
DK
Denmark
Prior art keywords
formula
lower alkyl
hydrogen
acceptable salts
pyrrol
Prior art date
Application number
DK400679A
Other languages
English (en)
Other versions
DK151803B (da
DK400679A (da
Inventor
Elvio Bellasio
Nunzio Di Mola
Ambrogio Campi
Emiliana Baldoli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of DK400679A publication Critical patent/DK400679A/da
Publication of DK151803B publication Critical patent/DK151803B/da
Application granted granted Critical
Publication of DK151803C publication Critical patent/DK151803C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
DK400679A 1978-10-02 1979-09-25 Analogifremgangsmaade til fremstilling af n-pyrrolylpyridazinaminderivater eller farmaceutisk acceptable salte deraf DK151803C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7838898 1978-10-02
GB7838898 1978-10-02

Publications (3)

Publication Number Publication Date
DK400679A DK400679A (da) 1980-04-03
DK151803B DK151803B (da) 1988-01-04
DK151803C true DK151803C (da) 1988-06-13

Family

ID=10500040

Family Applications (1)

Application Number Title Priority Date Filing Date
DK400679A DK151803C (da) 1978-10-02 1979-09-25 Analogifremgangsmaade til fremstilling af n-pyrrolylpyridazinaminderivater eller farmaceutisk acceptable salte deraf

Country Status (15)

Country Link
EP (1) EP0009655B1 (da)
JP (1) JPS5569577A (da)
AT (1) ATE3294T1 (da)
AU (1) AU529482B2 (da)
CA (1) CA1144165A (da)
DE (1) DE2965377D1 (da)
DK (1) DK151803C (da)
ES (1) ES484616A1 (da)
FI (1) FI65998C (da)
GR (1) GR69856B (da)
IE (1) IE49017B1 (da)
IL (1) IL58256A (da)
NO (1) NO151620C (da)
YU (1) YU41886B (da)
ZA (1) ZA794923B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
US5254622A (en) * 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
BRPI0412343A (pt) 2003-07-30 2006-09-05 Xenon Pharmaceuticals Inc derivados de piridazina e seu uso como agentes terapêuticos
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
CA2580857A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5094398B2 (ja) 2004-09-20 2012-12-12 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環式誘導体およびステアロイル−CoAデサチュラーゼのメディエータとしてのそれらの使用
MX2007003318A (es) 2004-09-20 2007-05-18 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
TW200626138A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
WO2006034441A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
WO2006034440A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
AU2006343359A1 (en) 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168334A (en) * 1967-01-25 1969-10-22 Lepetit Spa New Pharmacologically Active Pyridazines
GB1378102A (en) * 1972-03-14 1974-12-18 Lepetit Spa Antihypertensive compositions
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives
AU477837B2 (en) * 1973-05-30 1974-12-05 I. S. F. Sp. A New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.

Also Published As

Publication number Publication date
ZA794923B (en) 1980-09-24
GR69856B (da) 1982-07-19
YU41886B (en) 1988-02-29
FI65998B (fi) 1984-04-30
JPS5569577A (en) 1980-05-26
DK151803B (da) 1988-01-04
EP0009655A1 (en) 1980-04-16
ES484616A1 (es) 1980-05-16
DK400679A (da) 1980-04-03
AU529482B2 (en) 1983-06-09
NO151620B (no) 1985-01-28
IL58256A0 (en) 1979-12-30
IE791866L (en) 1980-04-02
NO151620C (no) 1985-05-08
DE2965377D1 (en) 1983-06-16
CA1144165A (en) 1983-04-05
IE49017B1 (en) 1985-07-10
EP0009655B1 (en) 1983-05-11
AU5086679A (en) 1980-04-17
ATE3294T1 (de) 1983-05-15
YU237479A (en) 1983-02-28
FI65998C (fi) 1984-08-10
NO793151L (no) 1980-04-08
JPH0321553B2 (da) 1991-03-22
IL58256A (en) 1984-02-29
FI792832A (fi) 1980-04-03

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Legal Events

Date Code Title Description
PBP Patent lapsed