FI62064C - Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel - Google Patents

Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel Download PDF

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Publication number
FI62064C
FI62064C FI3243/74A FI324374A FI62064C FI 62064 C FI62064 C FI 62064C FI 3243/74 A FI3243/74 A FI 3243/74A FI 324374 A FI324374 A FI 324374A FI 62064 C FI62064 C FI 62064C
Authority
FI
Finland
Prior art keywords
alkyl
group
hydrogen
compound
formula
Prior art date
Application number
FI3243/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI324374A (de
FI62064B (fi
Inventor
Harm Jan Panneman
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI324374A publication Critical patent/FI324374A/fi
Publication of FI62064B publication Critical patent/FI62064B/fi
Application granted granted Critical
Publication of FI62064C publication Critical patent/FI62064C/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI3243/74A 1973-11-09 1974-11-07 Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel FI62064C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL7315350A NL7315350A (nl) 1973-11-09 1973-11-09 Nieuwe aminoguanidine verbindingen.
NL7315350 1973-11-09

Publications (3)

Publication Number Publication Date
FI324374A FI324374A (de) 1975-05-10
FI62064B FI62064B (fi) 1982-07-30
FI62064C true FI62064C (fi) 1982-11-10

Family

ID=19819967

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3243/74A FI62064C (fi) 1973-11-09 1974-11-07 Foerfarande foer framstaellning av nya 2,6-disubstituerade fenylaminoguanidinfoereningar vilka aer anvaendbara saosom blodtrycknedsaettande laekemedel

Country Status (17)

Country Link
US (1) US3972932A (de)
JP (1) JPS5546389B2 (de)
AR (1) AR205358A1 (de)
BE (1) BE822019A (de)
CA (1) CA1032962A (de)
CH (1) CH616656A5 (de)
DE (1) DE2452691A1 (de)
DK (1) DK138791B (de)
ES (1) ES431775A1 (de)
FI (1) FI62064C (de)
FR (1) FR2250521B1 (de)
GB (1) GB1487852A (de)
HU (1) HU171856B (de)
IE (1) IE40409B1 (de)
NL (1) NL7315350A (de)
SE (1) SE420720B (de)
ZA (1) ZA746701B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141992A (en) * 1975-08-22 1979-02-27 American Cyanamid Company Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents
US4113776A (en) * 1976-04-15 1978-09-12 Hoffmann-La Roche Inc. 1-(2-Aminoethyl)-3-(2,6-dihalophenyl)guanidines
JPS5930330A (ja) * 1982-08-12 1984-02-17 Yaesu Musen Co Ltd デジタル周波数表示方式
HU190639B (en) * 1983-12-12 1986-09-29 Gyogyszerkutato Intezet Kv,Hu Process for production of new aminoguanidin derivatives
ZA857153B (en) * 1984-09-19 1986-05-28 Ciba Geigy Ag Substituted carbodiimides
ATE59633T1 (de) * 1984-09-19 1991-01-15 Ciba Geigy Ag Substituierte carbodiimide.
WO1991012797A1 (en) 1990-03-02 1991-09-05 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALF SCIENCES UNIVERSITY Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
DE69230220T2 (de) * 1991-02-08 2000-06-21 Cambridge Neuroscience Res Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
KR20030097618A (ko) * 1993-05-27 2003-12-31 캠브리지 뉴로사이언스, 인코포레이티드 치료용 치환 구아니딘류
JPH09505591A (ja) * 1993-11-23 1997-06-03 ケンブリッジ・ニューロサイエンス・インコーポレーテッド 治療用置換グアニジン類
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
KR100423272B1 (ko) 1994-02-03 2004-09-01 캠브리지 뉴로사이언스, 인코포레이티드 신경전달물질의방출을조절하는화합물,이의약학적으로허용가능한염및이를포함하는약학조성물
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
JP4739695B2 (ja) * 2004-06-07 2011-08-03 株式会社日本ファインケム ５−アミノ―１―置換―１，２，４―トリアゾールの製造方法、及び該製造方法で得られるトリアゾール誘導体
JP4564786B2 (ja) * 2004-06-07 2010-10-20 株式会社日本ファインケム １−置換―１―アミノグアニジン又はその塩、及びこれらの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB800869A (en) * 1955-09-28 1958-09-03 Ici Ltd Substituted amino-guanidines
NL7011683A (de) * 1970-08-07 1972-02-09

Also Published As

Publication number Publication date
NL7315350A (nl) 1975-05-13
FR2250521A1 (de) 1975-06-06
FR2250521B1 (de) 1979-03-16
FI324374A (de) 1975-05-10
DE2452691A1 (de) 1975-05-15
ZA746701B (en) 1975-11-26
SE420720B (sv) 1981-10-26
DK138791B (da) 1978-10-30
SE7414045L (de) 1975-05-12
US3972932A (en) 1976-08-03
FI62064B (fi) 1982-07-30
HU171856B (hu) 1978-04-28
ES431775A1 (es) 1976-12-16
GB1487852A (en) 1977-10-05
BE822019A (fr) 1975-05-09
IE40409L (en) 1975-05-09
IE40409B1 (en) 1979-05-23
CH616656A5 (de) 1980-04-15
DK579774A (de) 1975-07-07
CA1032962A (en) 1978-06-13
DK138791C (de) 1979-04-09
AR205358A1 (es) 1976-04-30
JPS5077328A (de) 1975-06-24
JPS5546389B2 (de) 1980-11-22

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