FI57417C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-substituerad-oxazolo-(4,5-b)-pyridiner - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-substituerad-oxazolo-(4,5-b)-pyridiner Download PDFInfo
- Publication number
- FI57417C FI57417C FI1657/73A FI165773A FI57417C FI 57417 C FI57417 C FI 57417C FI 1657/73 A FI1657/73 A FI 1657/73A FI 165773 A FI165773 A FI 165773A FI 57417 C FI57417 C FI 57417C
- Authority
- FI
- Finland
- Prior art keywords
- oxazolo
- acid
- pyridine
- preparation
- butyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI800611A FI58921C (fi) | 1972-06-14 | 1980-02-28 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-substituerade-oxazolo-(5,4-b)-pyridiner |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26289872A | 1972-06-14 | 1972-06-14 | |
US26289872 | 1972-06-14 | ||
BE147896A BE819177R (fr) | 1972-06-14 | 1974-08-26 | Oxazolo- et thiazolopyridines |
BE147896 | 1974-08-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI57417B FI57417B (fi) | 1980-04-30 |
FI57417C true FI57417C (fi) | 1980-08-11 |
Family
ID=25648082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI1657/73A FI57417C (fi) | 1972-06-14 | 1973-05-22 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 2-substituerad-oxazolo-(4,5-b)-pyridiner |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS5943475B2 (nl) |
AR (1) | AR208500A1 (nl) |
AT (1) | AT333277B (nl) |
AU (1) | AU472528B2 (nl) |
BE (2) | BE800868A (nl) |
CA (1) | CA1019741A (nl) |
CS (1) | CS178889B2 (nl) |
DD (1) | DD105237A5 (nl) |
DE (1) | DE2330109A1 (nl) |
DK (1) | DK152050C (nl) |
FI (1) | FI57417C (nl) |
FR (1) | FR2187356B1 (nl) |
GB (1) | GB1421619A (nl) |
LU (1) | LU67786A1 (nl) |
NL (1) | NL184836C (nl) |
SE (2) | SE401675B (nl) |
ZA (1) | ZA733760B (nl) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2527321A1 (de) * | 1975-06-19 | 1976-12-23 | Merck & Co Inc | Oxazol eckige klammer auf 4,5-b eckige klammer zu pyridine |
JPS527992A (en) * | 1975-07-04 | 1977-01-21 | Merck & Co Inc | Oxazolo *4*55b* pyridines |
NL187021C (nl) * | 1975-07-15 | 1991-05-01 | Merck & Co Inc | Werkwijze ter bereiding van een farmaceutisch preparaat met anti-inflammatoire werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte anti-inflammatoir werkzame 2-fenyl-oxazolo-(4,5-b)pyridinederivaten. |
US4011326A (en) * | 1975-07-29 | 1977-03-08 | Merck & Co., Inc. | 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents |
US4753673A (en) * | 1977-07-22 | 1988-06-28 | The Dow Chemical Company | Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use |
EP0001473B1 (en) * | 1977-08-12 | 1988-07-27 | Imperial Chemical Industries Plc | Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith |
JPS5461182A (en) * | 1977-10-20 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-phenoxy-5-trifluoromethylpyridine compounds |
JPS5461183A (en) * | 1977-10-21 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-substituted-5-trifluoromethyl pyridine compounds |
EP0003877B1 (en) * | 1978-02-15 | 1988-02-03 | Imperial Chemical Industries Plc | Herbicidal derivatives of 2-(4(2-pyridyloxy)phenoxy)propane, processes for preparing them, and herbicidal compositions containing them |
JPS55130840U (nl) * | 1979-03-12 | 1980-09-16 | ||
JPS55124763A (en) * | 1979-03-19 | 1980-09-26 | Ishihara Sangyo Kaisha Ltd | 5-trifluoromethyl-2-pyridone derivative |
GB8333514D0 (en) * | 1983-12-16 | 1984-01-25 | Erba Farmitalia | Tetrahydrothiazolo(5 4-c)pyridine derivatives |
FR2652085A1 (fr) * | 1989-09-20 | 1991-03-22 | Science Organisation | Nouveau procede de synthese de derives d'oxazolopyridines. |
WO1998021209A1 (de) * | 1996-11-11 | 1998-05-22 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue imidazo- und oxazolopyridine |
PL345906A1 (en) * | 1998-06-04 | 2002-01-14 | Abbott Lab | Cell adhesion-inhibiting antinflammatory compounds |
US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
EP1181296A1 (en) * | 1999-06-03 | 2002-02-27 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
WO2002036580A2 (en) * | 2000-10-31 | 2002-05-10 | Lynn Bonham | Benzoxazole lpaat- beta inhibitors and uses thereof |
US7855289B2 (en) | 2005-08-04 | 2010-12-21 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US8088928B2 (en) | 2005-08-04 | 2012-01-03 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US20070037865A1 (en) | 2005-08-04 | 2007-02-15 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US8093401B2 (en) | 2005-08-04 | 2012-01-10 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
CL2008001822A1 (es) | 2007-06-20 | 2009-03-13 | Sirtris Pharmaceuticals Inc | Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras. |
EP2320891B1 (en) * | 2008-08-29 | 2013-10-09 | Treventis Corporation | Butyrylcholinesterase ligands as diagnostic tools and treatment for deseases of the nervous system |
MX2011006555A (es) | 2008-12-19 | 2011-08-03 | Sirtris Pharmaceuticals Inc | Compuestos de tiazolopiridina moduladores de sirtuina. |
EP2482660A4 (en) * | 2009-09-30 | 2013-04-17 | Sumitomo Chemical Co | COMPOSITION AND METHOD FOR COMBATING HARMFUL ARTHROPODES |
CN103209695A (zh) * | 2010-09-15 | 2013-07-17 | 弗·哈夫曼-拉罗切有限公司 | 氮杂苯并噻唑化合物、组合物及应用方法 |
WO2012086848A1 (en) | 2010-12-24 | 2012-06-28 | Sumitomo Chemical Company, Limited | Fused heterocyclic compound and use for pest control thereof |
US20170217941A1 (en) * | 2014-06-25 | 2017-08-03 | Epizyme, Inc. | Substituted benzene and 6,5-fused bicyclic heteroaryl compounds |
BR112017011671A2 (pt) | 2014-12-02 | 2018-02-27 | Bayer Cropscience Aktiengesellschaft | compostos bicíclicos como agentes de controle de pragas. |
WO2017127627A1 (en) * | 2016-01-21 | 2017-07-27 | The University Of North Carolina At Chapel Hill | Compounds for treatment of trypanosomes and neurological pathogens and uses thereof |
CN109790132B (zh) * | 2016-07-07 | 2024-03-05 | 保土谷化学工业株式会社 | 具有苯并唑环结构的化合物及有机电致发光元件 |
-
1973
- 1973-03-12 AR AR248527A patent/AR208500A1/es active
- 1973-05-22 FI FI1657/73A patent/FI57417C/fi active
- 1973-05-24 DK DK284973A patent/DK152050C/da not_active IP Right Cessation
- 1973-05-25 SE SE7307412A patent/SE401675B/xx unknown
- 1973-05-30 NL NLAANVRAGE7307582,A patent/NL184836C/nl not_active IP Right Cessation
- 1973-06-04 AU AU56511/73A patent/AU472528B2/en not_active Expired
- 1973-06-04 ZA ZA00733760A patent/ZA733760B/xx unknown
- 1973-06-05 CA CA173,275A patent/CA1019741A/en not_active Expired
- 1973-06-08 AT AT508673A patent/AT333277B/de active
- 1973-06-11 GB GB2763273A patent/GB1421619A/en not_active Expired
- 1973-06-12 DD DD171559A patent/DD105237A5/xx unknown
- 1973-06-12 CS CS7300004243A patent/CS178889B2/cs unknown
- 1973-06-13 DE DE2330109A patent/DE2330109A1/de not_active Withdrawn
- 1973-06-13 FR FR7321443A patent/FR2187356B1/fr not_active Expired
- 1973-06-13 BE BE132231A patent/BE800868A/xx not_active IP Right Cessation
- 1973-06-13 LU LU67786A patent/LU67786A1/xx unknown
- 1973-06-14 JP JP48066453A patent/JPS5943475B2/ja not_active Expired
-
1974
- 1974-08-26 BE BE147896A patent/BE819177R/xx not_active IP Right Cessation
-
1976
- 1976-04-14 SE SE7604385A patent/SE432767B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DD105237A5 (nl) | 1974-04-12 |
NL7307582A (nl) | 1973-12-18 |
AT333277B (de) | 1976-11-10 |
JPS4961195A (nl) | 1974-06-13 |
GB1421619A (en) | 1976-01-21 |
SE7604385L (sv) | 1976-04-14 |
CS178889B2 (en) | 1977-10-31 |
ZA733760B (en) | 1975-01-29 |
DK152050B (da) | 1988-01-25 |
FI57417B (fi) | 1980-04-30 |
FR2187356B1 (nl) | 1977-01-28 |
NL184836C (nl) | 1989-11-16 |
JPS5943475B2 (ja) | 1984-10-22 |
BE800868A (fr) | 1973-12-13 |
BE819177R (fr) | 1975-02-26 |
ATA508673A (de) | 1976-03-15 |
AR208500A1 (es) | 1977-02-15 |
CA1019741A (en) | 1977-10-25 |
LU67786A1 (nl) | 1973-08-16 |
FR2187356A1 (nl) | 1974-01-18 |
AU472528B2 (en) | 1976-05-27 |
SE401675B (sv) | 1978-05-22 |
DK152050C (da) | 1988-07-18 |
SE432767B (sv) | 1984-04-16 |
DE2330109A1 (de) | 1974-01-03 |
AU5651173A (en) | 1974-12-05 |
NL184836B (nl) | 1989-06-16 |
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