FI56839B - Foerfarande foer framstaellning av nya antibakteriella penicillinderivat - Google Patents

Foerfarande foer framstaellning av nya antibakteriella penicillinderivat

Info

Publication number
FI56839B
FI56839B FI2897/72A FI289772A FI56839B FI 56839 B FI56839 B FI 56839B FI 2897/72 A FI2897/72 A FI 2897/72A FI 289772 A FI289772 A FI 289772A FI 56839 B FI56839 B FI 56839B
Authority
FI
Finland
Prior art keywords
penicillinderivat
antibakteriella
framework
procedure
antibakteriella penicillinderivat
Prior art date
Application number
FI2897/72A
Other languages
English (en)
Other versions
FI56839C (fi
Inventor
Hans-Bodo Koenig
Wilfried Schroeck
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of FI56839B publication Critical patent/FI56839B/fi
Publication of FI56839C publication Critical patent/FI56839C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
FI2897/72A 1971-10-23 1972-10-19 Foerfarande foer framstaellning av nya antibakteriella penicillinderivat FI56839C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2152967A DE2152967C3 (de) 1971-10-23 1971-10-23 Acylureidopenicilline
DE2152967 1971-10-23

Publications (2)

Publication Number Publication Date
FI56839B true FI56839B (fi) 1979-12-31
FI56839C FI56839C (fi) 1980-04-10

Family

ID=5823251

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2897/72A FI56839C (fi) 1971-10-23 1972-10-19 Foerfarande foer framstaellning av nya antibakteriella penicillinderivat

Country Status (31)

Country Link
JP (2) JPS57843B2 (fi)
AR (1) AR195805A1 (fi)
AT (1) AT320152B (fi)
BE (1) BE790440A (fi)
BG (2) BG21609A3 (fi)
CA (1) CA1019323A (fi)
CH (1) CH579089A5 (fi)
CS (1) CS188883B2 (fi)
CY (1) CY947A (fi)
DD (1) DD106044B3 (fi)
DE (1) DE2152967C3 (fi)
DK (1) DK134992C (fi)
EG (1) EG10826A (fi)
ES (1) ES407851A1 (fi)
FI (1) FI56839C (fi)
FR (1) FR2157908B1 (fi)
GB (1) GB1392849A (fi)
HK (1) HK18578A (fi)
HU (1) HU167986B (fi)
IE (1) IE37123B1 (fi)
IL (1) IL40628A (fi)
KE (1) KE2824A (fi)
LU (1) LU66332A1 (fi)
NO (1) NO143909C (fi)
PH (1) PH9893A (fi)
PL (2) PL93574B1 (fi)
RO (2) RO63066A (fi)
SE (1) SE412236B (fi)
SU (1) SU527139A3 (fi)
YU (1) YU264072A (fi)
ZA (1) ZA727473B (fi)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972869A (en) * 1971-10-23 1976-08-03 Bayer Aktiengesellschaft Penicillins
US3978056A (en) * 1971-10-23 1976-08-31 Bayer Aktiengesellschaft Penicillins
US4009272A (en) * 1971-10-23 1977-02-22 Bayer Aktiengesellschaft Penicillins
US3983105A (en) * 1971-10-23 1976-09-28 Bayer Aktiengesellschaft Penicillins
US3974141A (en) * 1971-10-23 1976-08-10 Bayer Aktiengesellschaft Penicillins
US3972870A (en) * 1971-10-23 1976-08-03 Bayer Aktiengesellschaft Penicillins
US3974142A (en) * 1971-10-23 1976-08-10 Bayer Aktiengesellschaft Penicillins
NL175419C (nl) * 1971-10-23 1984-11-01 Bayer Ag Werkwijze ter bereiding of vervaardiging van antibiotisch werkzame farmaceutische preparaten, alsmede werkwijze ter bereiding van antibiotisch werkzame alfa-gesubstitueerde 6-(alfa-(3-acylureido)acetylamino) penicillanzuurderivaten.
DE2258973A1 (de) * 1972-12-01 1974-06-06 Bayer Ag Penicilline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS587637B2 (ja) * 1973-12-27 1983-02-10 住友化学工業株式会社 シンキペニシリンノ セイホウ
DE2407715C2 (de) * 1974-02-18 1982-12-02 Bayer Ag, 5090 Leverkusen Cephalosporine, Verfahren zu ihrer Herstellung sowie Arzneimittel
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
DE2525541C2 (de) * 1975-06-07 1984-01-12 Bayer Ag, 5090 Leverkusen β-Lactam-Antibiotica, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel
DE2810083A1 (de) 1978-03-08 1979-09-20 Bayer Ag Beta-lactam-verbindungen
GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EP1780213A1 (en) * 2005-10-27 2007-05-02 3M Innovative Properties Company Silicon-urea-azolides, their preparation and use in the preparation of silicones with isocyanate terminal groups
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
CN101801951B (zh) 2007-09-14 2013-11-13 杨森制药有限公司 1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮
KR20100065191A (ko) 2007-09-14 2010-06-15 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 1,3-이치환된 4-(아릴-x-페닐)-1h-피리딘-2-온
TW200927731A (en) 2007-09-14 2009-07-01 Ortho Mcneil Janssen Pharm 1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
ES2637794T3 (es) 2007-11-14 2017-10-17 Janssen Pharmaceuticals, Inc. Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2
RU2510396C2 (ru) 2008-09-02 2014-03-27 Янссен Фармасьютикалз, Инк. 3-азабицикло[3.1.0]гексильные производные в качестве модуляторов метаботропных глутаматных рецепторов
BRPI0920354A2 (pt) 2008-10-16 2017-06-27 Addex Pharmaceuticals Sa derivados de indol e benzomorfolina como moduladores de receptores de glutamato metabotrópicos
AU2009319387B2 (en) 2008-11-28 2012-05-10 Addex Pharma S.A. Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
JP5707390B2 (ja) 2009-05-12 2015-04-30 ジャンセン ファーマシューティカルズ, インコーポレイテッド 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体の正のアロステリック調節因子としてのその使用
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
RS53075B (en) 2009-05-12 2014-04-30 Janssen Pharmaceuticals Inc. 1,2,4-TRIAZOLO [4,3-A] PYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
RU2586287C2 (ru) * 2009-06-10 2016-06-10 Текфилдз Байокем Ко., Лтд. Композиции или пролекарства противомикробных и родственных противомикробным соединений, обладающие высокой проникающей способностью
EP2649069B1 (en) 2010-11-08 2015-08-26 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
EP2661435B1 (en) 2010-11-08 2015-08-19 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
EP2643320B1 (en) 2010-11-08 2015-03-04 Janssen Pharmaceuticals, Inc. 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
DK3431106T3 (da) 2014-01-21 2021-03-15 Janssen Pharmaceutica Nv Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse
ES2860298T3 (es) 2014-01-21 2021-10-04 Janssen Pharmaceutica Nv Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770620A1 (de) * 1968-06-12 1971-11-11 Bayer Ag Neue Penicilline

Also Published As

Publication number Publication date
CY947A (en) 1978-06-23
NO143909C (no) 1981-05-06
JPS57843B2 (fi) 1982-01-08
DK134992B (da) 1977-02-21
ES407851A1 (es) 1975-10-01
BG21609A3 (fi) 1976-07-20
NO143909B (no) 1981-01-26
AR195805A1 (es) 1973-11-09
ZA727473B (en) 1973-07-25
RO63066A (fr) 1978-06-15
FR2157908B1 (fi) 1976-03-19
DE2152967C3 (de) 1981-11-19
IE37123B1 (en) 1977-05-11
JPS4849910A (fi) 1973-07-14
BE790440A (fi) 1973-04-24
FR2157908A1 (fi) 1973-06-08
DD106044A5 (fi) 1974-05-20
SU527139A3 (ru) 1976-08-30
FI56839C (fi) 1980-04-10
BG20813A3 (fi) 1975-12-20
DD106044B3 (de) 1990-07-18
HK18578A (en) 1978-04-14
PL89056B1 (fi) 1976-10-30
GB1392849A (en) 1975-04-30
IE37123L (en) 1973-04-23
HU167986B (fi) 1976-02-28
PH9893A (en) 1976-06-08
JPS55391B2 (fi) 1980-01-08
CA1019323A (en) 1977-10-18
RO60670A (fi) 1976-10-15
YU264072A (en) 1982-06-18
LU66332A1 (fi) 1973-01-23
DE2152967A1 (de) 1973-05-03
CS188883B2 (en) 1979-03-30
CH579089A5 (fi) 1976-08-31
AU4806472A (en) 1974-04-26
PL93574B1 (fi) 1977-06-30
KE2824A (en) 1978-04-07
SE412236B (sv) 1980-02-25
IL40628A0 (en) 1972-12-29
AT320152B (de) 1975-01-27
DK134992C (da) 1977-07-18
IL40628A (en) 1976-08-31
DE2152967B2 (de) 1981-02-19
JPS4849787A (fi) 1973-07-13
EG10826A (en) 1976-12-31

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