FI19992503A - Pichia pastoris-hiivan happaman fosfataasin geeni - Google Patents

Pichia pastoris-hiivan happaman fosfataasin geeni

Info

Publication number
FI19992503A
FI19992503A FI992503A FI19992503A FI19992503A FI 19992503 A FI19992503 A FI 19992503A FI 992503 A FI992503 A FI 992503A FI 19992503 A FI19992503 A FI 19992503A FI 19992503 A FI19992503 A FI 19992503A
Authority
FI
Finland
Prior art keywords
pichia pastoris
acid phosphatase
phosphatase gene
gene
acid
Prior art date
Application number
FI992503A
Other languages
English (en)
Swedish (sv)
Other versions
FI113474B (fi
Inventor
Richard G Buckholz
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Publication of FI19992503A publication Critical patent/FI19992503A/fi
Application granted granted Critical
Publication of FI113474B publication Critical patent/FI113474B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/938—Pichia

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI992503A 1990-12-14 1999-11-24 Pichia pastoris-hiivan happaman fosfataasin geenin DNA-kappale FI113474B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/627,539 US5268273A (en) 1990-12-14 1990-12-14 Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
US62753990 1990-12-14

Publications (2)

Publication Number Publication Date
FI19992503A true FI19992503A (fi) 1999-11-24
FI113474B FI113474B (fi) 2004-04-30

Family

ID=24515081

Family Applications (2)

Application Number Title Priority Date Filing Date
FI915893A FI104493B (fi) 1990-12-14 1991-12-13 Pichia pastoris-hiivan happaman fosfataasin geeni
FI992503A FI113474B (fi) 1990-12-14 1999-11-24 Pichia pastoris-hiivan happaman fosfataasin geenin DNA-kappale

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI915893A FI104493B (fi) 1990-12-14 1991-12-13 Pichia pastoris-hiivan happaman fosfataasin geeni

Country Status (22)

Country Link
US (1) US5268273A (fi)
EP (1) EP0495208B1 (fi)
JP (1) JP3437850B2 (fi)
KR (1) KR0181179B1 (fi)
CN (1) CN1062169A (fi)
AR (1) AR245218A1 (fi)
AT (1) ATE208822T1 (fi)
AU (1) AU637734B2 (fi)
CA (1) CA2055542C (fi)
CS (1) CS378891A3 (fi)
DE (1) DE69132812T2 (fi)
FI (2) FI104493B (fi)
HU (1) HU913926D0 (fi)
IE (1) IE914354A1 (fi)
IL (1) IL100363A0 (fi)
MX (1) MX9102546A (fi)
NO (1) NO314151B1 (fi)
PL (1) PL292765A1 (fi)
PT (1) PT99802A (fi)
TW (1) TW201330B (fi)
YU (1) YU193591A (fi)
ZA (1) ZA919776B (fi)

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US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
GB9307371D0 (en) * 1993-04-08 1993-06-02 Walls Alan J Fusion proteins
US5521086A (en) * 1993-09-16 1996-05-28 Cephalon, Inc. Secretion sequence for the production of a heterologous protein in yeast
IT1266740B1 (it) * 1994-07-01 1997-01-14 Maria Paola Landini Materiale proteico ricombinante legante anticorpi contro il citomegalovirus umano, reagenti diagnostici derivati da tale
JP3811186B2 (ja) * 1994-10-18 2006-08-16 コーバス インターナショナル， インコーポレイテッド 線虫から抽出されるセリンプロテアーゼ阻害剤および抗凝固性タンパク質
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP0877816A1 (en) * 1996-02-01 1998-11-18 North American Vaccine, Inc. Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines
MX9605082A (es) 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
WO1999007862A1 (en) * 1997-08-05 1999-02-18 Chiron Corporation Novel pichia pastoris gene sequences and methods for their use
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
US6309869B1 (en) 1999-01-14 2001-10-30 Novozymes Biotech, Inc. Polypeptides having acid phosphatase activity and nucleic acids encoding same
EP1165806B1 (en) 1999-03-31 2005-08-03 Cornell Research Foundation, Inc. Phosphatases with improved phytase activity
US6841370B1 (en) * 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
CN1320699A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——人磷脂酶9和编码这种多肽的多核苷酸
CN1324948A (zh) * 2000-05-24 2001-12-05 上海博德基因开发有限公司 一种新的多肽——酸性磷酸酶14和编码这种多肽的多核苷酸
US6605450B1 (en) 2000-05-25 2003-08-12 Chiron Corporation Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use
CN1329020A (zh) * 2000-06-21 2002-01-02 上海博德基因开发有限公司 一种新的多肽——酸性磷酸酶家族蛋白11和编码这种多肽的多核苷酸
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
US7320876B2 (en) 2001-10-31 2008-01-22 Phytex, Llc Phytase-containing animal food and method
EP1604008B1 (en) * 2002-09-13 2010-12-22 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
JP2007519392A (ja) 2003-07-30 2007-07-19 ザイモジェネティクス， インコーポレイテッド ピキアメタノリカ分泌シグナル
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
WO2007137300A2 (en) 2006-05-23 2007-11-29 Bellicum Pharmaceuticals, Inc. Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
US8540984B2 (en) 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
US8097422B2 (en) 2007-06-20 2012-01-17 Salk Institute For Biological Studies Kir channel modulators
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
SG188846A1 (en) 2008-03-03 2013-04-30 Abbott Lab Methods for transforming yeast
US20090280103A1 (en) * 2008-04-04 2009-11-12 Martin Flueck Regulation of muscle repair
JP2012531903A (ja) 2009-07-02 2012-12-13 バーデザイン， インコーポレイテッド アジピン酸を調製する生物学的方法
CA2767361A1 (en) 2009-07-09 2011-01-13 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
US8889394B2 (en) * 2009-09-07 2014-11-18 Empire Technology Development Llc Multiple domain proteins
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
CA2841794C (en) 2011-07-06 2019-08-13 Verdezyne, Inc. Genetically modified yeast with increased alcohol dehydrogenase activity for preparing a fatty dicarboxylic acid
KR102079293B1 (ko) 2012-10-29 2020-02-19 론자 리미티드 발현 서열
SG11201504838YA (en) 2012-12-19 2015-07-30 Verdezyne Inc Biological methods for preparing a fatty dicarboxylic acid
US9909151B2 (en) 2012-12-19 2018-03-06 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
EP3943607A1 (en) 2014-04-09 2022-01-26 The Scripps Research Institute Import of unnatural or modified nucleoside triphosphates into cells via nucleic acid triphosphate transporters
CN104195059B (zh) * 2014-08-15 2016-08-24 陕西科技大学 多形汉逊酵母突变菌株及多形汉逊酵母生产d-***糖醇的方法
US20180148744A1 (en) 2015-03-20 2018-05-31 Verdezyne, Inc. Biological methods for preparing 3-hydroxypropionic acid
US10988515B2 (en) 2017-01-13 2021-04-27 Bolt Threads, Inc. Elastomeric proteins
CN111051512A (zh) 2017-07-11 2020-04-21 辛索克斯公司 非天然核苷酸的掺入及其方法
MX2020000366A (es) 2017-07-13 2020-08-17 Radici Chimica S P A Métodos biológicos para la modificación de flujo de carbono celular.
TWI757528B (zh) 2017-08-03 2022-03-11 美商欣爍克斯公司 用於增生及感染性疾病治療之細胞激素結合物
WO2020060948A1 (en) 2018-09-17 2020-03-26 Levadura Biotechnology, Inc. Production of cannabinoids in yeast using a fatty acid feedstock
CA3127689A1 (en) 2019-02-06 2020-08-13 Synthorx, Inc. Il-2 conjugates and methods of use thereof

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JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
DE3588149T2 (de) * 1984-10-01 1997-10-09 Genzyme Corp Rekombinante DNS-Verfahren und dadurch hergestellte Produkte
US4885242A (en) * 1984-10-30 1989-12-05 Phillips Petroleum Company Genes from pichia histidine pathway and uses thereof
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4808537A (en) * 1984-10-30 1989-02-28 Phillips Petroleum Company Methanol inducible genes obtained from pichia and methods of use
US4882279A (en) * 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
JPH0655146B2 (ja) * 1985-12-27 1994-07-27 財団法人化学及血清療法研究所 シヤトルベクタ−
IL82935A0 (en) * 1986-08-12 1987-12-20 Phillips Petroleum Co Secretion of heterologous proteins from yeast
US5002876A (en) * 1986-09-22 1991-03-26 Phillips Petroleum Company Yeast production of human tumor necrosis factor
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Also Published As

Publication number Publication date
IE914354A1 (en) 1992-06-17
NO914935D0 (no) 1991-12-13
ATE208822T1 (de) 2001-11-15
ZA919776B (en) 1992-09-30
NO314151B1 (no) 2003-02-03
FI113474B (fi) 2004-04-30
KR920012442A (ko) 1992-07-27
DE69132812T2 (de) 2002-06-20
IL100363A0 (en) 1992-09-06
YU193591A (sh) 1994-06-10
PL292765A1 (en) 1992-08-24
KR0181179B1 (ko) 1999-04-01
TW201330B (fi) 1993-03-01
US5268273A (en) 1993-12-07
EP0495208B1 (en) 2001-11-14
FI915893A (fi) 1992-06-15
CA2055542A1 (en) 1992-06-15
JP3437850B2 (ja) 2003-08-18
DE69132812D1 (de) 2001-12-20
MX9102546A (es) 1992-07-01
CN1062169A (zh) 1992-06-24
AU637734B2 (en) 1993-06-03
CS378891A3 (en) 1992-06-17
FI915893A0 (fi) 1991-12-13
PT99802A (pt) 1992-12-31
AU8882391A (en) 1992-06-25
JPH0576371A (ja) 1993-03-30
HU913926D0 (en) 1992-02-28
EP0495208A3 (en) 1994-05-18
FI104493B (fi) 2000-02-15
AR245218A1 (es) 1993-12-30
CA2055542C (en) 1999-08-31
EP0495208A2 (en) 1992-07-22
NO914935L (no) 1992-06-15

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