ES8900253A1 - Un procedimiento para la preparacion de derivados de piperazinilo 1,4disustituidos - Google Patents
Un procedimiento para la preparacion de derivados de piperazinilo 1,4disustituidosInfo
- Publication number
- ES8900253A1 ES8900253A1 ES557855A ES557855A ES8900253A1 ES 8900253 A1 ES8900253 A1 ES 8900253A1 ES 557855 A ES557855 A ES 557855A ES 557855 A ES557855 A ES 557855A ES 8900253 A1 ES8900253 A1 ES 8900253A1
- Authority
- ES
- Spain
- Prior art keywords
- furo
- substituent
- piperazinyl
- derivatives
- antipsychotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE DESCRIBEN EN LA PRESENTE INVENCION DERIVADOS DE PIPERACINILO 1, 4-DISUSTITUIDOS DE FORMULA I, ASI COMO SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES; EN LOS QUE UN SUSTITUYENTE ES UN HETEROCICLICO DE ANILLOFUSIONADO BICICLICO DE FURO-, PIRROLO-, CILCOPENTADIENO-, O TIENO-PIRIDINA, Y EL SEGUNDO SUSTITUYENTE ES UNA CADENA DE ALQUILENO UNIDA A HETEROCICLICOS DE IMIDIDA CICLICA O UNA PARTE CARBINOL BENCILICA. LOS COMPUESTOS DE LA PRESENTE INVENCION SON AGENTES FARMACOLOGICOS UTILES CON PROPIEDADES PSICOTROPICAS; Y PRESENTAN ACTIVIDAD SELECTIVA SOBRE EL SISTEMA NERVIOSO CENTRAL, SIENDO DE PARTICULAR INTERES COMO AGENTES ANTIPSICOTICOS. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73120185A | 1985-05-06 | 1985-05-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557855A0 ES557855A0 (es) | 1989-05-16 |
ES8900253A1 true ES8900253A1 (es) | 1989-05-16 |
Family
ID=24938510
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES554659A Expired ES8801250A1 (es) | 1985-05-06 | 1986-05-05 | Un procedimiento para la preparacion de derivados de piperazimilo 1,4-di sustituidos. |
ES557757A Expired ES8802149A1 (es) | 1985-05-06 | 1987-09-25 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4-disustituidos |
ES557809A Expired ES8802614A1 (es) | 1985-05-06 | 1988-01-28 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4 disustituidos |
ES557839A Expired ES8900138A1 (es) | 1985-05-06 | 1988-05-26 | Un procedimiento para la preparacion de derivados de piperazinilo 1-4-disustituidos. |
ES557855A Expired ES8900253A1 (es) | 1985-05-06 | 1988-11-16 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4disustituidos |
ES557865A Expired ES9000005A1 (es) | 1985-05-06 | 1989-02-27 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4-disustituidos |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES554659A Expired ES8801250A1 (es) | 1985-05-06 | 1986-05-05 | Un procedimiento para la preparacion de derivados de piperazimilo 1,4-di sustituidos. |
ES557757A Expired ES8802149A1 (es) | 1985-05-06 | 1987-09-25 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4-disustituidos |
ES557809A Expired ES8802614A1 (es) | 1985-05-06 | 1988-01-28 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4 disustituidos |
ES557839A Expired ES8900138A1 (es) | 1985-05-06 | 1988-05-26 | Un procedimiento para la preparacion de derivados de piperazinilo 1-4-disustituidos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557865A Expired ES9000005A1 (es) | 1985-05-06 | 1989-02-27 | Un procedimiento para la preparacion de derivados de piperazinilo 1,4-disustituidos |
Country Status (25)
Country | Link |
---|---|
JP (1) | JPH0753728B2 (es) |
KR (1) | KR940000829B1 (es) |
CN (1) | CN1017901B (es) |
AT (1) | AT398572B (es) |
AU (1) | AU593244B2 (es) |
BE (1) | BE904724A (es) |
CA (1) | CA1278792C (es) |
CH (1) | CH672787A5 (es) |
DE (1) | DE3615180C2 (es) |
DK (1) | DK165745C (es) |
EG (1) | EG18206A (es) |
ES (6) | ES8801250A1 (es) |
FI (1) | FI85484C (es) |
FR (1) | FR2581385B1 (es) |
GB (1) | GB2174703B (es) |
GR (1) | GR861149B (es) |
HU (1) | HU195509B (es) |
IE (1) | IE59201B1 (es) |
IT (1) | IT1208607B (es) |
LU (1) | LU86421A1 (es) |
MY (1) | MY100777A (es) |
NL (1) | NL8601146A (es) |
PT (1) | PT82523B (es) |
SE (1) | SE465270B (es) |
ZA (1) | ZA862046B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5801186A (en) | 1987-11-20 | 1998-09-01 | Hoechst Marion Roussel, Inc. | 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds |
US4880930A (en) * | 1987-11-30 | 1989-11-14 | New James S | Psychotropic acyclic amide derivatives |
US4780466A (en) * | 1988-03-17 | 1988-10-25 | Hoechst-Roussel Pharmaceuticals, Inc. | Arylpiperazinylalkoxy derivatives of cyclic imides |
IE903410A1 (en) * | 1989-10-09 | 1991-04-10 | Novo Nordisk As | Indole derivatives, their preparation and use |
US5272148A (en) * | 1992-09-09 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals Incorporated | Heteroarenylpiperazines |
CN1094490C (zh) * | 1995-09-15 | 2002-11-20 | 圣诺菲合成实验室公司 | 作为血清素拮抗剂的喹诺-2(1h)-酮衍生物 |
FR2738822B1 (fr) * | 1995-09-15 | 1997-10-31 | Synthelabo | Derives de 4-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique |
FR2738823B1 (fr) * | 1995-09-15 | 1997-10-31 | Synthelabo | Derives de 3-(omega-(4-(thieno(3,2-c)pyridin-4-yl)piperazin- 1-yl)alkyl)-3,4-dihydroquinolein-2(1h)-one,leur preparation et leur application en therapeutique |
FR2738824B1 (fr) * | 1995-09-15 | 1997-10-31 | Synthelabo | Derives de 3-(omega(4-(thieno(3,2-c)pyridin-4-yl)piperazin-1 -yl)alkyl)-3,4-dihydroquinazolin-2(1h)-one,leur preparation et leur application en therapeutique |
FR2761071B1 (fr) * | 1997-03-20 | 1999-12-03 | Synthelabo | Derives de quinolein-2(1h)-one et de dihydroquinolein-2(1h)- one, leur preparation et leur application en therapeutique |
FR2797874B1 (fr) * | 1999-08-27 | 2002-03-29 | Adir | Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4367335A (en) * | 1981-08-03 | 1983-01-04 | Mead Johnson & Company | Thiazolidinylalkylene piperazine derivatives |
US4452799A (en) * | 1981-12-23 | 1984-06-05 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
US4361565A (en) * | 1981-12-28 | 1982-11-30 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
-
1986
- 1986-03-11 CA CA000503794A patent/CA1278792C/en not_active Expired - Fee Related
- 1986-03-19 ZA ZA862046A patent/ZA862046B/xx unknown
- 1986-04-29 EG EG250/86A patent/EG18206A/xx active
- 1986-04-29 AU AU56795/86A patent/AU593244B2/en not_active Expired
- 1986-04-29 GR GR861149A patent/GR861149B/el unknown
- 1986-04-30 FI FI861820A patent/FI85484C/fi not_active IP Right Cessation
- 1986-05-02 KR KR1019860003445A patent/KR940000829B1/ko not_active IP Right Cessation
- 1986-05-02 GB GB08610810A patent/GB2174703B/en not_active Expired
- 1986-05-05 LU LU86421A patent/LU86421A1/fr unknown
- 1986-05-05 SE SE8602061A patent/SE465270B/sv not_active IP Right Cessation
- 1986-05-05 FR FR8606471A patent/FR2581385B1/fr not_active Expired - Lifetime
- 1986-05-05 DE DE3615180A patent/DE3615180C2/de not_active Expired - Lifetime
- 1986-05-05 ES ES554659A patent/ES8801250A1/es not_active Expired
- 1986-05-05 CH CH1830/86A patent/CH672787A5/de not_active IP Right Cessation
- 1986-05-05 IE IE119386A patent/IE59201B1/en not_active IP Right Cessation
- 1986-05-05 DK DK207186A patent/DK165745C/da not_active IP Right Cessation
- 1986-05-05 CN CN86103071A patent/CN1017901B/zh not_active Expired
- 1986-05-05 BE BE0/216623A patent/BE904724A/fr not_active IP Right Cessation
- 1986-05-05 NL NL8601146A patent/NL8601146A/nl active Search and Examination
- 1986-05-06 AT AT0121486A patent/AT398572B/de not_active IP Right Cessation
- 1986-05-06 HU HU861860A patent/HU195509B/hu unknown
- 1986-05-06 JP JP61103726A patent/JPH0753728B2/ja not_active Expired - Lifetime
- 1986-05-06 IT IT8620313A patent/IT1208607B/it active
- 1986-05-06 PT PT82523A patent/PT82523B/pt unknown
-
1987
- 1987-09-25 ES ES557757A patent/ES8802149A1/es not_active Expired
- 1987-10-01 MY MYPI87002712A patent/MY100777A/en unknown
-
1988
- 1988-01-28 ES ES557809A patent/ES8802614A1/es not_active Expired
- 1988-05-26 ES ES557839A patent/ES8900138A1/es not_active Expired
- 1988-11-16 ES ES557855A patent/ES8900253A1/es not_active Expired
-
1989
- 1989-02-27 ES ES557865A patent/ES9000005A1/es not_active Expired
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20060307 |