ES8706827A1 - Procedimiento para preparar polipeptidos. - Google Patents
Procedimiento para preparar polipeptidos.Info
- Publication number
- ES8706827A1 ES8706827A1 ES557193A ES557193A ES8706827A1 ES 8706827 A1 ES8706827 A1 ES 8706827A1 ES 557193 A ES557193 A ES 557193A ES 557193 A ES557193 A ES 557193A ES 8706827 A1 ES8706827 A1 ES 8706827A1
- Authority
- ES
- Spain
- Prior art keywords
- polypeptides
- dna molecules
- molecules encoding
- hrv2
- rhinovirus strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 241000709661 Enterovirus Species 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 241000430519 Human rhinovirus sp. Species 0.000 abstract 1
- 108010067390 Viral Proteins Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32711—Rhinovirus
- C12N2770/32722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN POLIPEPTIDO QUE TIENE LA ACTIVIDAD BIOLOGICA DE POR LO MENOS UNA DE LA PROTEINAS VIRICAS DE LA CEPA DE RINOVIRUS HRV2, QUE CONTIENE LAS SECUENCIAS DDE AMINOACIDOS PARA VP1, VP2, VP3, VP4, P2A, P2B, P2C, P3A O P3C, Y QUE SE FIJA A LOS RECEPTORES CELULARES PARA LOS RINOVIRUS CEPA HRV2 O BLOQUEA A ESTOS. COMPRENDE LAS SIGUIENTES OPERACIOENS: PRIMERA, SE TRANSFORMA UN ORGANISMO HOSPEDANTE APROPIADO, PREFERIBLEMENTE UN PROCARIOTA, EUCARIOTA O UNA LINEA DE CELULAS DE MAMIFERO, ESPECIALMENTE E. COLI, CON INFORMACIONES GENETICAS QUE CODIFICAN UN POLIPEPTIDO VIRICO, PREFERIBLEMENTE CON INFORMACIONES GENETICAS; SEGUNDA, LA INFORMACION ES EXPRESADA AL OBJETO DE PRODUCIR UN POLIPEPTIDO VIRICO EN EL ORGANISMO HOSPEDANTE; Y POR ULTIMO, SE AISLA EL POLIPEPTIDO VIRICO. DE APLICACION EN EL TRATAMIENTO GENERAL DE ENFRIAMIENTOS EN LOS HUMANOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853505148 DE3505148A1 (de) | 1985-02-15 | 1985-02-15 | Polypeptide des rhinovirusstammes hrv2 sowie die hierfuer codierenden dna-molekuele |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557193A0 ES557193A0 (es) | 1987-06-16 |
ES8706827A1 true ES8706827A1 (es) | 1987-06-16 |
Family
ID=6262562
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552026A Expired ES8704207A1 (es) | 1985-02-15 | 1986-02-14 | Procedimiento para preparar una molecula de adn |
ES557193A Expired ES8706827A1 (es) | 1985-02-15 | 1986-11-04 | Procedimiento para preparar polipeptidos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552026A Expired ES8704207A1 (es) | 1985-02-15 | 1986-02-14 | Procedimiento para preparar una molecula de adn |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0192175A3 (es) |
JP (1) | JPS62279A (es) |
KR (1) | KR860006547A (es) |
AU (1) | AU599895B2 (es) |
DE (1) | DE3505148A1 (es) |
DK (1) | DK71986A (es) |
ES (2) | ES8704207A1 (es) |
FI (1) | FI860677A (es) |
GR (1) | GR860432B (es) |
NO (1) | NO860550L (es) |
NZ (1) | NZ215173A (es) |
PT (1) | PT82026B (es) |
ZA (1) | ZA861100B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0261403A3 (de) * | 1986-08-23 | 1988-04-13 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Polypeptide des Rhinovirusstammes HRV89 sowie die hierfür codierenden DNA-Moleküle |
GB8709274D0 (en) * | 1987-04-16 | 1987-05-20 | Wellcome Found | Peptides |
EP0321973B1 (de) * | 1987-12-23 | 1993-11-03 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Expression der viral kodierten Protease P2A des HRV2 |
EP0356695B1 (de) * | 1988-07-25 | 1995-01-04 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | in vitro Synthese einer infektiösen RNA |
US6143298A (en) * | 1988-09-01 | 2000-11-07 | Bayer Corporation | Soluble truncated forms of ICAM-1 |
US6051231A (en) * | 1988-09-01 | 2000-04-18 | Bayer Corporation | Antiviral methods and prepations |
DE68929096T2 (de) | 1988-09-01 | 2000-05-11 | Bayer Corp., Pittsburgh | Menschliches Rhinovirusrezeptorprotein, das die Virusinfektionsanfälligkeit hemmt |
US6514936B1 (en) | 1988-09-01 | 2003-02-04 | Bayer Corporation | Antiviral methods using human rhinovirus receptor (ICAM-1) |
ZA896668B (en) * | 1988-09-01 | 1990-06-27 | Molecular Therapeutics Inc | A human rhinovirus receptor protein that inhibits virus infectivity |
ES2134762T3 (es) * | 1990-07-20 | 1999-10-16 | Bayer Ag | Formas multimericas de proteinas receptoras de rinovirus humanos. |
US5871733A (en) * | 1990-07-20 | 1999-02-16 | Bayer Corporation | Multimeric forms of human rhinovirus receptor protein |
US5674982A (en) * | 1990-07-20 | 1997-10-07 | Bayer Corporation | Multimeric form of human rhinovirus receptor protein |
US6107461A (en) * | 1990-07-20 | 2000-08-22 | Bayer Corporation | Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use |
DE4027154A1 (de) * | 1990-08-28 | 1992-03-05 | Boehringer Ingelheim Int | Mutation der hrv2 2a |
DE4136443A1 (de) * | 1991-11-06 | 1993-05-13 | Boehringer Ingelheim Int | Expression der reifen proteinase 2a, ihre partielle reinigung und bereitstellung kompetitiv wirkender substrate |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8303501A (nl) * | 1983-10-12 | 1985-05-01 | Centraal Diergeneeskundig Inst | Deletiemutant van een herpesvirus en vaccin, dat dit virus bevat. |
CA1339735C (en) * | 1984-04-27 | 1998-03-17 | Ian Hamilton Holmes. | Cloning and sequencing of the major outer capsid gylcoprotein gene of a human rotavirus |
EP0169146A3 (en) * | 1984-07-20 | 1988-07-20 | Merck & Co. Inc. | Monoclonal antibodies directed against the cellular receptor of human rhinovirus |
AU5736286A (en) * | 1985-05-14 | 1986-11-20 | Commonwealth Scientific And Industrial Research Organisation | Rotavirus antigens |
-
1985
- 1985-02-15 DE DE19853505148 patent/DE3505148A1/de not_active Ceased
-
1986
- 1986-02-12 EP EP86101746A patent/EP0192175A3/de not_active Ceased
- 1986-02-13 GR GR860432A patent/GR860432B/el unknown
- 1986-02-14 FI FI860677A patent/FI860677A/fi not_active IP Right Cessation
- 1986-02-14 PT PT82026A patent/PT82026B/pt not_active IP Right Cessation
- 1986-02-14 ES ES552026A patent/ES8704207A1/es not_active Expired
- 1986-02-14 NZ NZ215173A patent/NZ215173A/en unknown
- 1986-02-14 NO NO860550A patent/NO860550L/no unknown
- 1986-02-14 ZA ZA861100A patent/ZA861100B/xx unknown
- 1986-02-14 AU AU53610/86A patent/AU599895B2/en not_active Ceased
- 1986-02-14 JP JP61030592A patent/JPS62279A/ja active Pending
- 1986-02-14 DK DK71986A patent/DK71986A/da not_active Application Discontinuation
- 1986-02-15 KR KR1019860001053A patent/KR860006547A/ko not_active Application Discontinuation
- 1986-11-04 ES ES557193A patent/ES8706827A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8704207A1 (es) | 1987-03-16 |
ZA861100B (en) | 1987-10-28 |
JPS62279A (ja) | 1987-01-06 |
KR860006547A (ko) | 1986-09-13 |
ES557193A0 (es) | 1987-06-16 |
ES552026A0 (es) | 1987-03-16 |
PT82026B (pt) | 1988-07-01 |
DK71986D0 (da) | 1986-02-14 |
EP0192175A2 (de) | 1986-08-27 |
DK71986A (da) | 1986-08-16 |
AU599895B2 (en) | 1990-08-02 |
DE3505148A1 (de) | 1986-10-30 |
NZ215173A (en) | 1991-07-26 |
PT82026A (de) | 1986-03-01 |
FI860677A (fi) | 1986-08-16 |
EP0192175A3 (de) | 1988-01-20 |
AU5361086A (en) | 1986-08-21 |
GR860432B (en) | 1986-06-12 |
FI860677A0 (fi) | 1986-02-14 |
NO860550L (no) | 1986-08-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8602121A1 (es) | Procedimiento para producir un vehiculo de expresion para la formacion de uroquinasa humana | |
ZA91134B (en) | New proteins produced by human lymphocytes,dna sequence encoding these proteins and their pharmaceutical and biological uses | |
ES8706827A1 (es) | Procedimiento para preparar polipeptidos. | |
MD430C2 (ro) | Procedeu de obţinere a interferonelor leucocitare umane | |
AU2964489A (en) | Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides | |
ATE182901T1 (de) | Für androgen-rezeptor-protein kodierende dna | |
ZA86217B (en) | Dna sequences,recombinant dna molecules and processes for producing human lipocortin-like polypeptides | |
DE68914664D1 (de) | Gereinigte ubiquitin-hydrolase, diese kodierende dns-sequenzen und ihre verwendung zur gewinnung von polypeptiden. | |
AU8223387A (en) | Horse gamma-interferon | |
IL80562A0 (en) | Recombinant human lysozyme,its preparation by recombinant dna technology and pharmaceutical compositions containing it | |
AU6745287A (en) | Dna sequences coding for proteins having the biological activity of husi-type i inhibitors, biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins | |
EP0209543A4 (en) | FRAGMENTS OF HUMAN APOLIPOPROTEINS PEPTIDES, TYPE-SPECIFIC ANTIBODIES AND METHODS OF USE. | |
IL87391A0 (en) | Hiv proteins and peptides,dna coding therefor,vectors comprising such dna,the use of the proteins and peptides in diagnosis of aids and vaccine compositions containing them | |
DE3881023D1 (de) | Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten. | |
ZA876248B (en) | Polypeptides of the rhinovirus strain hrv89 and the dna molecules coding therefor | |
AU617982B2 (en) | Polypeptides of the rhinovirus strain HRV89 and the DNA molecules coding therefor | |
GB2171703B (en) | Expression-secretion vector for gene expression and protein secretion, recombinant dna including the vector, and method of producing proteins by use of the re | |
EP0315081A3 (en) | Anti-coagulating protein pp4-x, its preparation and use | |
WO1990003394A3 (fr) | Nouvelles lymphokines, sequences d'adn codant pour ces lymphokines et compositions pharmaceutiques contenant ces lymphokines | |
EP0452319A4 (en) | PROTEIN AND CODING SEQUENCE FOR DETECTING AND DIFFERENTIATING SIV AND HIV-2 GROUPS OF VIRUSES. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |