ATE182901T1 - Für androgen-rezeptor-protein kodierende dna - Google Patents

Für androgen-rezeptor-protein kodierende dna

Info

Publication number
ATE182901T1
ATE182901T1 AT89905317T AT89905317T ATE182901T1 AT E182901 T1 ATE182901 T1 AT E182901T1 AT 89905317 T AT89905317 T AT 89905317T AT 89905317 T AT89905317 T AT 89905317T AT E182901 T1 ATE182901 T1 AT E182901T1
Authority
AT
Austria
Prior art keywords
receptor protein
androgen receptor
dna coding
human androgen
polypeptides
Prior art date
Application number
AT89905317T
Other languages
English (en)
Inventor
Frank S French
Elisabeth M Wilson
David R Joseph
Dennis B Lubahn
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Application granted granted Critical
Publication of ATE182901T1 publication Critical patent/ATE182901T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT89905317T 1988-04-15 1989-04-13 Für androgen-rezeptor-protein kodierende dna ATE182901T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,646 US6307030B1 (en) 1988-04-15 1988-04-15 Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions

Publications (1)

Publication Number Publication Date
ATE182901T1 true ATE182901T1 (de) 1999-08-15

Family

ID=22669419

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89905317T ATE182901T1 (de) 1988-04-15 1989-04-13 Für androgen-rezeptor-protein kodierende dna

Country Status (7)

Country Link
US (3) US6307030B1 (de)
EP (1) EP0365657B1 (de)
JP (1) JP3385380B2 (de)
AT (1) ATE182901T1 (de)
CA (1) CA1341347C (de)
DE (1) DE68929043T2 (de)
WO (1) WO1989009791A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614620A (en) * 1988-03-30 1997-03-25 Arch Development Corporation DNA binding proteins including androgen receptor
US6307030B1 (en) 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions
WO1991007423A1 (en) * 1989-11-17 1991-05-30 Arch Development Corporation Dna binding proteins including androgen receptor
CA2239976A1 (en) * 1995-09-20 1997-03-27 Paul A. Zamecnik Antisense oligonucleotide chemotherapy for benign hyperplasia or cancer of the prostate
EP0948542B1 (de) 1996-09-11 2007-07-04 Oregon Health Sciences University Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen.
AU4494399A (en) * 1998-06-30 2000-01-24 University Of British Columbia, The Inhibitors of androgen-independent activation of androgen receptor
DE19834180A1 (de) 1998-07-29 2000-02-03 Benckiser Nv Zusammensetzung zur Verwendung in einer Geschirrspülmaschine
CA2446819A1 (en) 2001-05-08 2002-11-14 Merck & Co., Inc. Dna molecules encoding macaca mulatta androgen receptor
WO2003012394A2 (en) * 2001-07-27 2003-02-13 University Of Rochester Androgen receptor knock-out transgenic animals
CA2517027A1 (en) 2002-02-25 2003-09-04 Vaxiion Therapeutics, Inc. Minicell compositions and methods
JP2006510370A (ja) * 2002-12-20 2006-03-30 バイオディテクション・システムズ・ベスローテン・フェンノートシャップ 試料中の一つ以上のリガンドの存在を決定する方法
US7467119B2 (en) * 2003-07-21 2008-12-16 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US7505948B2 (en) * 2003-11-18 2009-03-17 Aureon Laboratories, Inc. Support vector regression for censored data
WO2005050563A2 (en) * 2003-11-17 2005-06-02 Aureon Biosciences Corporation Pathological tissue mapping
ATE502298T1 (de) * 2003-12-19 2011-04-15 Univ California Verfahren und materialien zur beurteilung von prostatakrebstherapien
WO2005099693A2 (en) 2004-02-24 2005-10-27 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
EP1728210A2 (de) * 2004-02-27 2006-12-06 Aureon Laboratories, Inc. Verfahren und system zur vorhersage des auftretens eines ereignisses
WO2006020627A1 (en) * 2004-08-11 2006-02-23 Aureon Laboratories, Inc. Systems and methods for automated diagnosis and grading of tissue images
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
KR100777082B1 (ko) 2005-08-30 2007-11-28 주식회사 엘지생활건강 올리고뉴클레오타이드를 포함하는 피지분비 억제용 화장료조성물
EP2656841B1 (de) * 2006-03-27 2016-08-10 The Regents of The University of California Androgenrezeptor-Modulator zur Behandlung von Prostatakrebs und Androgenrezeptor-assoziierte Erkrankungen
CN102755318B (zh) 2006-03-29 2014-09-10 加利福尼亚大学董事会 二芳基硫代乙内酰脲化合物
AU2007254134A1 (en) * 2006-05-19 2007-11-29 University Of Rochester Prostate epithelial androgen receptor suppresses prostate growth and tumor invasion
US7910565B2 (en) 2006-09-01 2011-03-22 Wisconsin Alumni Research Foundation Prostate cancer vaccine
WO2008116262A1 (en) * 2007-03-27 2008-10-02 Christopher Hovens Methods and compositions for treating prostate cancer
JP5535925B2 (ja) 2007-10-26 2014-07-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア アンドロゲン受容体調節物質としてのジアリールヒダントイン化合物
WO2010015036A1 (en) * 2008-08-08 2010-02-11 Christopher Hovens Biological applications of steroid binding domains
US8841422B2 (en) 2008-09-17 2014-09-23 University Of Maryland, Baltimore Human androgen receptor alternative splice variants
US8133724B2 (en) * 2008-09-17 2012-03-13 University Of Maryland, Baltimore Human androgen receptor alternative splice variants as biomarkers and therapeutic targets
GB0921873D0 (en) * 2009-12-15 2010-01-27 Cytosystems Ltd Assay
SI3124481T1 (en) 2010-02-16 2018-06-29 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and their use
SI3305285T1 (sl) 2012-09-26 2021-03-31 Aragon Pharmaceuticals, Inc. Anti-androgeni za zdravljenje proti kastraciji odpornega ne-metastatskega raka
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
JP6668255B2 (ja) 2014-04-30 2020-03-25 エクスプレッション、パソロジー、インコーポレイテッドＥｘｐｒｅｓｓｉｏｎ Ｐａｔｈｏｌｏｇｙ， Ｉｎｃ． アンドロゲン受容体（ａｒ）タンパク質のｓｒｍ／ｍｒｍアッセイ
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JP7201694B2 (ja) 2017-10-16 2023-01-10 アラゴン ファーマシューティカルズ，インコーポレイテッド 非転移性去勢抵抗性前立腺癌の治療のための抗アンドロゲン剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423208A (en) 1982-02-24 1983-12-27 Peter Grandics Affinity gel-adsorbent
WO1987005049A1 (en) 1986-02-20 1987-08-27 California Biotechnology Inc. Eucaryotic expression of steroid receptor proteins
EP0407462A4 (en) 1988-03-30 1992-02-05 Arch Development Corporation Dna binding proteins including androgen receptor
US5614620A (en) * 1988-03-30 1997-03-25 Arch Development Corporation DNA binding proteins including androgen receptor
US6307030B1 (en) 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions

Also Published As

Publication number Publication date
WO1989009791A1 (en) 1989-10-19
US20050079576A1 (en) 2005-04-14
DE68929043D1 (de) 1999-09-09
US6307030B1 (en) 2001-10-23
EP0365657A1 (de) 1990-05-02
US7129078B2 (en) 2006-10-31
JPH03500605A (ja) 1991-02-14
DE68929043T2 (de) 2000-04-13
CA1341347C (en) 2002-03-12
EP0365657A4 (en) 1991-08-21
EP0365657B1 (de) 1999-08-04
US6821767B1 (en) 2004-11-23
JP3385380B2 (ja) 2003-03-10

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