ES8700324A1 - Un metodo de detectar un primer compuesto que comprende al menos un resto de base en una muesta - Google Patents

Un metodo de detectar un primer compuesto que comprende al menos un resto de base en una muesta

Info

Publication number
ES8700324A1
ES8700324A1 ES539316A ES539316A ES8700324A1 ES 8700324 A1 ES8700324 A1 ES 8700324A1 ES 539316 A ES539316 A ES 539316A ES 539316 A ES539316 A ES 539316A ES 8700324 A1 ES8700324 A1 ES 8700324A1
Authority
ES
Spain
Prior art keywords
polynucleotides
utilizing
preparing
methods
labeled nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539316A
Other languages
English (en)
Other versions
ES539316A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzo Biochem Inc
Original Assignee
Enzo Biochem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23546604&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8700324(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Enzo Biochem Inc filed Critical Enzo Biochem Inc
Publication of ES539316A0 publication Critical patent/ES539316A0/es
Publication of ES8700324A1 publication Critical patent/ES8700324A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

METODO DE DETECCION DE UN PRIMER COMPUESTO QUE COMPRENDE AL MENOS UN RESTO DE BASE EN UNA MUESTRA, EMPLEANDO NUCLEOTIDOS O POLINUCLEOTIDOS QUE SE MARCAN RADIACTIVAMENTE CON ISOTOPOS O HIDROGENO (3H), FOSFORO (32P), CARBONO (14C) O YODO (125I). EL METODO COMPRENDE LAS OPERACIONES DE PONER EN CONTACTO UN PRIMER COMPUESTO CON UN SEGUNDO COMPUESTO QUE TIENE UNIDO COVALENTEMENTE UN RESTO DE BASE, UN RESTO DE AZUCAR Y UN RESTO QUE CONTIENE P, POR UN RESTO QUIMICO CAPAZ DE COMPLEJAR IONES. LOS NUCLEOTIDOS MODIFICADOS DE ACUERDO CON ESTE INVENTO Y MARCADO RADIACTIVAMENTE CON HIDRO-3, FOSFORO-32, CARBONO-14 O YODO-125 SON UTILES PARA DETECTAR, COMPROBAR, LOCALIZAR Y AISLAR ACIDOS NUCLEICOS Y OTRAS MOLECULAS DE INTERES CIENTIFICO O CLINICO, Y COMO SONDAS EN INVESTIGACION BIOMEDICA, DIAGNOSIS CLINICA Y TECNOLOGIA DE ADN RECOMBINANTE. INCLUSO DETECTAR E IDENTIFICAR AGENTES ETIOLOGICOS QUE CONTIENE ACIDO NUCLEICO Y SELECCIONAR BACTERIAS PARA LA RESISTENCIA A LOS ANTIBIOTICOS.
ES539316A 1982-06-23 1985-01-02 Un metodo de detectar un primer compuesto que comprende al menos un resto de base en una muesta Expired ES8700324A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39144082A 1982-06-23 1982-06-23

Publications (2)

Publication Number Publication Date
ES539316A0 ES539316A0 (es) 1986-10-01
ES8700324A1 true ES8700324A1 (es) 1986-10-01

Family

ID=23546604

Family Applications (4)

Application Number Title Priority Date Filing Date
ES523503A Expired ES8700270A1 (es) 1982-06-23 1983-06-22 Un metodo para producir nucleotidos.
ES539316A Expired ES8700324A1 (es) 1982-06-23 1985-01-02 Un metodo de detectar un primer compuesto que comprende al menos un resto de base en una muesta
ES547319A Expired ES8802257A1 (es) 1982-06-23 1985-09-26 Un metodo para detectar cuantitativamente una secuencia seleccionada de oligo-o-poli-desoxinucleotido en una muestra.
ES547320A Expired ES8606903A1 (es) 1982-06-23 1985-09-26 Un metodo para entregar un agente seleccionado a un lugar biologico caracterizado por la presencia de una secuencia de adn seleccionada.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES523503A Expired ES8700270A1 (es) 1982-06-23 1983-06-22 Un metodo para producir nucleotidos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES547319A Expired ES8802257A1 (es) 1982-06-23 1985-09-26 Un metodo para detectar cuantitativamente una secuencia seleccionada de oligo-o-poli-desoxinucleotido en una muestra.
ES547320A Expired ES8606903A1 (es) 1982-06-23 1985-09-26 Un metodo para entregar un agente seleccionado a un lugar biologico caracterizado por la presencia de una secuencia de adn seleccionada.

Country Status (11)

Country Link
US (2) US6992180B1 (es)
EP (7) EP0285058A3 (es)
JP (4) JP2625095B2 (es)
AT (3) ATE119164T1 (es)
AU (2) AU585199B2 (es)
CA (1) CA1223831A (es)
DE (3) DE3382782T2 (es)
DK (1) DK291183A (es)
ES (4) ES8700270A1 (es)
IL (1) IL69051A (es)
NO (1) NO832292L (es)

Families Citing this family (207)

* Cited by examiner, † Cited by third party
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EP0302175A2 (en) 1989-02-08
DE3382822D1 (de) 1998-06-04
ES8606903A1 (es) 1986-03-16
EP0618228A1 (en) 1994-10-05
US8097405B1 (en) 2012-01-17
EP0286898B1 (en) 1998-04-29
EP0286898A3 (en) 1990-08-08
ES547319A0 (es) 1988-04-16
EP0285950A2 (en) 1988-10-12
EP0302175A3 (en) 1990-10-31
US6992180B1 (en) 2006-01-31
EP0285058A2 (en) 1988-10-05
AU1617983A (en) 1984-01-05
JP2760466B2 (ja) 1998-05-28
ES8700270A1 (es) 1986-09-16
EP0285057A2 (en) 1988-10-05
EP0285057B1 (en) 1995-03-01
AU4149389A (en) 1990-01-04
AU585199B2 (en) 1989-06-15
DE3382782D1 (de) 1995-04-06
EP0097373A3 (en) 1984-06-06
JPH11292892A (ja) 1999-10-26
DK291183A (da) 1983-12-24
EP0286898A2 (en) 1988-10-19
IL69051A0 (en) 1983-10-31
ATE165605T1 (de) 1998-05-15
DE3382626D1 (de) 1992-11-12
ES523503A0 (es) 1986-09-16
ES539316A0 (es) 1986-10-01
IL69051A (en) 1988-02-29
DE3382626T2 (de) 1993-05-06
JPH06234787A (ja) 1994-08-23
JPS5962600A (ja) 1984-04-10
JPH10158294A (ja) 1998-06-16
NO832292L (no) 1983-12-27
ATE119164T1 (de) 1995-03-15
JP2625095B2 (ja) 1997-06-25
ATE81342T1 (de) 1992-10-15
CA1223831A (en) 1987-07-07
DE3382782T2 (de) 1995-10-19
DE3382822T2 (de) 1998-11-19
DK291183D0 (da) 1983-06-23
EP0285058A3 (en) 1990-09-26
EP0285057A3 (en) 1990-10-31
EP0285950A3 (en) 1990-11-07
JP3170235B2 (ja) 2001-05-28
ES547320A0 (es) 1986-03-16
ES8802257A1 (es) 1988-04-16
EP0097373B1 (en) 1992-10-07
EP0097373A2 (en) 1984-01-04

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