ES8604918A1 - Un procedimiento para la preparacion de ranitidina - Google Patents

Un procedimiento para la preparacion de ranitidina

Info

Publication number
ES8604918A1
ES8604918A1 ES547108A ES547108A ES8604918A1 ES 8604918 A1 ES8604918 A1 ES 8604918A1 ES 547108 A ES547108 A ES 547108A ES 547108 A ES547108 A ES 547108A ES 8604918 A1 ES8604918 A1 ES 8604918A1
Authority
ES
Spain
Prior art keywords
methyl
preparation
furan derivative
methylsulphinylmethide
ranitidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547108A
Other languages
English (en)
Other versions
ES547108A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES547108A0 publication Critical patent/ES547108A0/es
Publication of ES8604918A1 publication Critical patent/ES8604918A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE RANITIDINA. CONSISTE EN TRATAR UN COMPUESTO DE FORMULA (II) DONDE R REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO METILO, CON UN AGENTE METILANTE TAL COMO HALURO DE METILO, SULFATO DE METILO O UN ESTER METILSULFONICO, PARA OBTENER RANITIDINA DE FORMULA (I). LA OPERACION SE REALIZA EN PRESENCIA DE UNA BASE TAL COMO CARBONATO SODICO, CARBONATO POTASICO, BICARBONATO POTASICO, PIRIDINA O TRIETILAMINA, EN PRESENCIA DE UNA SAL DE METILSULFINILMETURO DE METAL ALCALINO QUE SE PREPARA IN SITU A PARTIR DE UN HIDRURO DE METAL ALCALINO Y DIMETILSULFOXIDO, REALIZANDOSE A UNA TEMPERATURA ENTRE 0 Y 50JC.
ES547108A 1984-09-20 1985-09-19 Un procedimiento para la preparacion de ranitidina Expired ES8604918A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848423804A GB8423804D0 (en) 1984-09-20 1984-09-20 Chemical process

Publications (2)

Publication Number Publication Date
ES547108A0 ES547108A0 (es) 1986-02-16
ES8604918A1 true ES8604918A1 (es) 1986-02-16

Family

ID=10567015

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547108A Expired ES8604918A1 (es) 1984-09-20 1985-09-19 Un procedimiento para la preparacion de ranitidina

Country Status (11)

Country Link
JP (1) JPS61106566A (es)
KR (1) KR870001166B1 (es)
AT (1) AT392639B (es)
CA (1) CA1237440A (es)
DK (1) DK426085A (es)
ES (1) ES8604918A1 (es)
FI (1) FI853599L (es)
GB (2) GB8423804D0 (es)
GR (1) GR852283B (es)
IT (1) IT1200117B (es)
PT (1) PT81161B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
NL8303965A (nl) * 1982-12-08 1984-07-02 Degussa Nieuwe etheendiamine- en guanidine-derivaten; werkwijze voor het bereiden daarvan; geneesmiddelen die ze bevatten; werkwijze voor het bereiden van dergelijke geneesmiddelen; toepassing van de verbindingen voor het bereiden van geneesmiddelen en in de geneeskunde.

Also Published As

Publication number Publication date
FI853599L (fi) 1986-03-21
KR860002488A (ko) 1986-04-26
AT392639B (de) 1991-05-10
ES547108A0 (es) 1986-02-16
JPS61106566A (ja) 1986-05-24
KR870001166B1 (ko) 1987-06-15
GR852283B (es) 1985-12-23
PT81161B (pt) 1988-01-22
FI853599A0 (fi) 1985-09-19
GB2164647B (en) 1988-02-03
GB8423804D0 (en) 1984-10-24
GB2164647A (en) 1986-03-26
PT81161A (en) 1985-10-01
ATA274085A (de) 1990-10-15
IT1200117B (it) 1989-01-05
IT8548572A0 (it) 1985-09-19
GB8523178D0 (en) 1985-10-23
DK426085A (da) 1986-03-21
CA1237440A (en) 1988-05-31
DK426085D0 (da) 1985-09-19

Similar Documents

Publication Publication Date Title
JPS5353642A (en) Preparation of alpha,alpha-dimethylbenzyl-isocyanate or its nuclear-substituted derivatives
IE792329L (en) Thiazaheterocyclics and process for preparing pyrrolidine¹and piperidine derivatives.
ES454063A1 (es) Un procedimiento para la preparacion de nuevos derivados delalcohol bencilico.
ES8604918A1 (es) Un procedimiento para la preparacion de ranitidina
ES8104213A1 (es) Procedimiento para la preparacion de acido 4,4'dinitro es- tilben-2,2'-disulfonico y sus sales
ES8307236A1 (es) Un procedimiento para la preparacion de ranitidina.
JPS5225740A (en) Preparation of o-acyl-amidinophenols or acid addition salts thereof
ATE109140T1 (de) Herstellung von piperidinylcyclopentylheptensäure-derivaten.
EP0490224A3 (de) Salicylaldehyd- und Salicylsäurederivate sowie deren Schwefelanaloge, Verfahren und Zwischenprodukte zu ihrer Herstellung
JPS55105666A (en) Piperidine derivative
JPS5233641A (en) Process for preparation of 4-substituted-alpha -methyl-glycidic acid salts
JPS527919A (en) Process for preparation of beta-sulfenylacrylic acid and its salt
JPS5214720A (en) Process for preparation of sodium malate hydrate
JPS5618971A (en) Alpha-halogeno-beta-benzosulfimidopropionitrile and its preparation
JPS5618933A (en) Dihydroxy aluminum salt of substituted acetic acid and its preparation
IE832579L (en) Titanium ester compositions
EP0111569A4 (en) HYDROXYALCANESULFONIC ACIDS, DERIVATIVES THEREOF AND PROCESS FOR THEIR PREPARATION.
JPS5227748A (en) Preparation of novel prostaglandin derivatives
JPS55104275A (en) Sulfur-containing compound
DE3666952D1 (en) 1-hydroxypyrazole-4-carboxylic acid, process for its preparation and its use
JPS5728070A (en) Monosodium salt dihydrate of 1,2,3-triazole-5-thiol and its preparation
GB1533914A (en) Salts of the monophosphoric acid ester of 2,2'-dihydroxy-3,3',5,5'-tetrabromobiphenyl
JPS5731651A (en) Cyclopropane-1-carboxylic acid derivative and its salt, their manufacture and application to synthesis of cis-pyrethrinoid intermediate
JPS5524139A (en) Optically active intermediate and its preparation
JPS52151121A (en) Beta-sulfenylacrylic acids and their derivatives