ES8506580A1 - Un procedimiento para la produccion de compuestos poliprenilicos - Google Patents

Un procedimiento para la produccion de compuestos poliprenilicos

Info

Publication number
ES8506580A1
ES8506580A1 ES530666A ES530666A ES8506580A1 ES 8506580 A1 ES8506580 A1 ES 8506580A1 ES 530666 A ES530666 A ES 530666A ES 530666 A ES530666 A ES 530666A ES 8506580 A1 ES8506580 A1 ES 8506580A1
Authority
ES
Spain
Prior art keywords
formula
group
image
polyprenyl compounds
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530666A
Other languages
English (en)
Other versions
ES530666A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8506580A1 publication Critical patent/ES8506580A1/es
Publication of ES530666A0 publication Critical patent/ES530666A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/64Monocyclic acids with unsaturation outside the aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS POLIPRENILICOS, DE FORMULA (I), EN LA QUE R2 REPRESENTA UN GRUPO ALQUILO INFERIOR.CONSISTE EN LA REACCION DE UNA POLIPRENILCETONA, DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN LA QUE R2 TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE LA AMBIENTE Y 70JC; DESPUES DE LO CUAL, EL COMPUESTO FORMADO SE EXTRAE SIGUIENDO METODOS CONVENCIONALES.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA PREVENCION Y EL TRATAMIENTO DEL CANCER O PRE-CANCER, ENFERMEDADES DERMICAS Y DE LAS MEMBRANAS MUCOSAS.
ES530666A 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos Granted ES530666A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57106204A JPS58225039A (ja) 1982-06-22 1982-06-22 ポリプレニル系化合物

Publications (2)

Publication Number Publication Date
ES8506580A1 true ES8506580A1 (es) 1985-08-01
ES530666A0 ES530666A0 (es) 1985-08-01

Family

ID=14427627

Family Applications (4)

Application Number Title Priority Date Filing Date
ES523441A Granted ES523441A0 (es) 1982-06-22 1983-06-20 Un procedimiento para la produccion de compuestos poliprenilicos.
ES530666A Granted ES530666A0 (es) 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos
ES530665A Expired ES8506579A1 (es) 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos
ES530664A Expired ES8506578A1 (es) 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES523441A Granted ES523441A0 (es) 1982-06-22 1983-06-20 Un procedimiento para la produccion de compuestos poliprenilicos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES530665A Expired ES8506579A1 (es) 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos
ES530664A Expired ES8506578A1 (es) 1982-06-22 1984-03-15 Un procedimiento para la produccion de compuestos poliprenilicos

Country Status (17)

Country Link
US (1) US4482734A (es)
JP (1) JPS58225039A (es)
KR (1) KR870000766B1 (es)
AT (1) AT392270B (es)
AU (1) AU555373B2 (es)
BE (1) BE897099A (es)
CA (1) CA1211461A (es)
CH (1) CH654292A5 (es)
DE (1) DE3320544A1 (es)
DK (1) DK160295C (es)
ES (4) ES523441A0 (es)
FR (1) FR2528829B1 (es)
GB (1) GB2124619B (es)
IT (1) IT1163573B (es)
NL (1) NL8302059A (es)
PH (1) PH17973A (es)
SE (1) SE445734B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0629218B2 (ja) * 1985-03-15 1994-04-20 エーザイ株式会社 ポリプレニル系化合物
US4670465A (en) * 1986-05-21 1987-06-02 Syntex (U.S.A.) Inc. Arachidonic acid analogs
JPH02120194U (es) * 1989-03-14 1990-09-27
ES2470369T3 (es) * 2002-05-17 2014-06-23 Kowa Company, Ltd. Inhibidores de la expresión de TGF-a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1292141B (de) * 1966-03-08 1969-04-10 Giulini Gmbh Geb Trisubstituierte Acrylsaeuren, deren Alkalisalze und ein Verfahren zu deren Herstellung
JPS54163545A (en) * 1978-06-10 1979-12-26 Taisho Pharmaceutical Co Ltd Organic carboxylic acid derivative
DE3022599A1 (de) * 1979-06-18 1981-01-08 Glaxo Group Ltd Alkansaeurederivate
US4390476A (en) * 1980-05-15 1983-06-28 Ciba-Geigy Corporation Phosphonium compounds, a process for their preparation and a process for the preparation of asymmetrically substituted stilbene fluorescent brightening agents

Also Published As

Publication number Publication date
KR840005067A (ko) 1984-11-03
IT1163573B (it) 1987-04-08
AU555373B2 (en) 1986-09-18
DK283783A (da) 1983-12-23
CH654292A5 (fr) 1986-02-14
GB2124619A (en) 1984-02-22
ES530665A0 (es) 1985-08-01
DK160295C (da) 1991-07-29
SE8303569L (sv) 1983-12-23
ES8501359A1 (es) 1984-11-16
US4482734A (en) 1984-11-13
ATA228183A (de) 1990-08-15
IT8321743A0 (it) 1983-06-22
BE897099A (fr) 1983-12-21
DK283783D0 (da) 1983-06-20
ES8506579A1 (es) 1985-08-01
PH17973A (en) 1985-02-22
GB8316781D0 (en) 1983-07-27
ES530664A0 (es) 1985-08-01
ES523441A0 (es) 1984-11-16
SE445734B (sv) 1986-07-14
JPS58225039A (ja) 1983-12-27
CA1211461A (en) 1986-09-16
JPS6361299B2 (es) 1988-11-28
AT392270B (de) 1991-02-25
ES530666A0 (es) 1985-08-01
FR2528829A1 (fr) 1983-12-23
FR2528829B1 (fr) 1986-04-11
DE3320544C2 (es) 1991-06-13
GB2124619B (en) 1985-10-23
KR870000766B1 (ko) 1987-04-15
AU1527683A (en) 1984-01-05
DE3320544A1 (de) 1983-12-22
DK160295B (da) 1991-02-25
SE8303569D0 (sv) 1983-06-21
NL8302059A (nl) 1984-01-16
ES8506578A1 (es) 1985-08-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040601