ES8500274A1 - Procedimiento para preparar un derivado de pirazolpiridina. - Google Patents

Procedimiento para preparar un derivado de pirazolpiridina.

Info

Publication number
ES8500274A1
ES8500274A1 ES523288A ES523288A ES8500274A1 ES 8500274 A1 ES8500274 A1 ES 8500274A1 ES 523288 A ES523288 A ES 523288A ES 523288 A ES523288 A ES 523288A ES 8500274 A1 ES8500274 A1 ES 8500274A1
Authority
ES
Spain
Prior art keywords
pyrazolo
pyridine
treating arthritis
dimethyl carbamoyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523288A
Other languages
English (en)
Other versions
ES523288A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of ES523288A0 publication Critical patent/ES523288A0/es
Publication of ES8500274A1 publication Critical patent/ES8500274A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE PIRAZOLPIRIDINA, EN PARTICULAR PARA PREPARAR 3-(N,N-DIMETILCARBAMOIL PIRAZOL1,5-APIRIDINA, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UN HALURO DE ACIDO DE FORMULA GENERAL (II), EN LA QUE X REPRESENTA UN ATOMO DE HALOGENO, CON DIMETILAMINA.DE APLICACION EN EL TRATAMIENTO DE DESORDENES ARTRITICOS, TAL COMO LA ARTRITIS REUMATOIDE.
ES523288A 1982-06-16 1983-06-15 Procedimiento para preparar un derivado de pirazolpiridina. Expired ES8500274A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8217485 1982-06-16

Publications (2)

Publication Number Publication Date
ES523288A0 ES523288A0 (es) 1984-10-01
ES8500274A1 true ES8500274A1 (es) 1984-10-01

Family

ID=10531092

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523288A Expired ES8500274A1 (es) 1982-06-16 1983-06-15 Procedimiento para preparar un derivado de pirazolpiridina.

Country Status (21)

Country Link
US (1) US4604400A (es)
JP (1) JPS595185A (es)
KR (1) KR840005139A (es)
AT (1) AT381312B (es)
AU (1) AU556031B2 (es)
BE (1) BE897068A (es)
CH (1) CH658053A5 (es)
DE (1) DE3321674A1 (es)
DK (1) DK275083A (es)
ES (1) ES8500274A1 (es)
FI (1) FI832173L (es)
FR (1) FR2528846B1 (es)
GR (1) GR79314B (es)
HU (1) HU187922B (es)
IL (1) IL68996A0 (es)
IT (1) IT1169734B (es)
LU (1) LU84860A1 (es)
NL (1) NL8302134A (es)
NZ (1) NZ204589A (es)
SE (1) SE8303435L (es)
ZA (1) ZA834408B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925849A (en) * 1987-06-15 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutically useful pyrazolopyridines
GB8901423D0 (en) * 1989-01-23 1989-03-15 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof
US8940726B2 (en) 2012-12-21 2015-01-27 Epizyme, Inc. PRMT5 inhibitors and uses thereof
US9604930B2 (en) 2012-12-21 2017-03-28 Epizyme, Inc. Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof
EP2935240A1 (en) 2012-12-21 2015-10-28 Epizyme, Inc. Prmt5 inhibitors and uses thereof
US10118918B2 (en) 2012-12-21 2018-11-06 Epizyme, Inc. PRMT5 inhibitors and uses thereof
WO2014100716A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
CA2953572A1 (en) 2014-08-04 2016-02-11 Epizyme, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5154583A (en) * 1974-11-01 1976-05-13 Kyorin Seiyaku Kk Shinkipirazoro * 1 55a * pirijinjudotaino seizoho
JPS5610114A (en) * 1979-07-05 1981-02-02 Grelan Pharmaceut Co Ltd Novel analgesic and anti-inflammatory agent
JPS5651478A (en) * 1979-10-02 1981-05-09 Grelan Pharmaceut Co Ltd 3-carbamoyl-pyrazolo 1,5-a pyridine and its preparation

Also Published As

Publication number Publication date
DE3321674A1 (de) 1983-12-22
FI832173A0 (fi) 1983-06-15
ES523288A0 (es) 1984-10-01
AU1577083A (en) 1983-12-22
ZA834408B (en) 1984-03-28
IT8321635A0 (it) 1983-06-15
CH658053A5 (fr) 1986-10-15
FR2528846A1 (fr) 1983-12-23
HU187922B (en) 1986-03-28
BE897068A (fr) 1983-12-16
NL8302134A (nl) 1984-01-16
DK275083D0 (da) 1983-06-15
US4604400A (en) 1986-08-05
IT1169734B (it) 1987-06-03
AT381312B (de) 1986-09-25
IL68996A0 (en) 1983-10-31
LU84860A1 (fr) 1984-03-07
DK275083A (da) 1983-12-17
ATA221183A (de) 1986-02-15
JPS595185A (ja) 1984-01-12
KR840005139A (ko) 1984-11-03
NZ204589A (en) 1985-12-13
GR79314B (es) 1984-10-22
AU556031B2 (en) 1986-10-16
SE8303435L (sv) 1983-12-17
FI832173L (fi) 1983-12-17
FR2528846B1 (fr) 1986-08-22
SE8303435D0 (sv) 1983-06-15

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