ES8404186A1 - "un procedimiento para obtener al menos un polipeptido que presenta la antigenicidad de los antigenos e del virus de la hepatitis b". - Google Patents
"un procedimiento para obtener al menos un polipeptido que presenta la antigenicidad de los antigenos e del virus de la hepatitis b".Info
- Publication number
- ES8404186A1 ES8404186A1 ES515418A ES515418A ES8404186A1 ES 8404186 A1 ES8404186 A1 ES 8404186A1 ES 515418 A ES515418 A ES 515418A ES 515418 A ES515418 A ES 515418A ES 8404186 A1 ES8404186 A1 ES 8404186A1
- Authority
- ES
- Spain
- Prior art keywords
- antigens
- methods
- virus
- hepatitis
- antigenicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/22—Viral peptide or viral protein
- Y10S930/223—Hepatitis related
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/31—Linker sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, EN UN CULTIVO ADECUADO SE COLOCA UN ORGANISMO HOSPEDANTE TRANSFORMADO CON UNA MOLECULA DE ADN RECOMBINANTE; SEGUNDA, SE PREPARA UN EXTRACTO A PARTIR DE LA FERMENTACION GENERADA POR EL ORGANISMO HOSPEDANTE, QUE CONTIENE EL ANTIGENO DE NUCLEO DE VIRUS DE LA HEPATITIS B; Y POR ULTIMO, SE CONVIERTE EL ANTIGENO DE NUCLEO DE VIRUS DE LA HEPATITIS B, CONTENIDO EN DICHO EXTRACTO, EN EL ANTIGENO E DEL VIRUS DE LA HEPATITIS B POR TRATAMIENTO DEL CITADO EXTRACTO CON UN AGENTE REDUCTOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8126583 | 1981-09-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES515418A0 ES515418A0 (es) | 1984-04-16 |
ES8404186A1 true ES8404186A1 (es) | 1984-04-16 |
Family
ID=10524270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES515418A Expired ES8404186A1 (es) | 1981-09-02 | 1982-09-01 | "un procedimiento para obtener al menos un polipeptido que presenta la antigenicidad de los antigenos e del virus de la hepatitis b". |
Country Status (9)
Country | Link |
---|---|
US (2) | US4563423A (es) |
EP (1) | EP0075395A3 (es) |
JP (3) | JPS5852228A (es) |
AU (1) | AU8746582A (es) |
CA (1) | CA1209502A (es) |
DK (1) | DK389682A (es) |
ES (1) | ES8404186A1 (es) |
FI (1) | FI823021L (es) |
ZA (1) | ZA826310B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8321789D0 (en) * | 1983-08-12 | 1983-09-14 | Biogen Nv | Vaccines and compositions against hepatitis |
US4722891A (en) * | 1984-06-20 | 1988-02-02 | Board Of Regents, The University Of Texas System | Methods and compositions for detection of Legionnaires' disease |
JPS6137738A (ja) * | 1984-07-31 | 1986-02-22 | Tetsuo Nakamura | B型肝炎ワクチン |
JPS61103895A (ja) * | 1984-10-26 | 1986-05-22 | Green Cross Corp:The | HBsAgの精製方法 |
US6534285B1 (en) | 1984-12-24 | 2003-03-18 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
US5853978A (en) * | 1985-12-04 | 1998-12-29 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and methods of use |
JPS61233700A (ja) * | 1984-12-24 | 1986-10-17 | ジエネンテク,インコ−ポレイテツド | 分子クロ−ンされたエイズ関連ポリペプチド |
EP0232410A4 (en) * | 1985-08-15 | 1988-01-25 | Amgen | CLEAVAGE PROCESS AND BUFFER FOR THE EXTRACTION OF HEPATITIS B SURFACE ANTIGENS FROM YEAR CELLS. |
JPH084507B2 (ja) * | 1985-10-03 | 1996-01-24 | 武田薬品工業株式会社 | 新規dnaおよびポリペプチド |
EP0272483A1 (en) * | 1986-12-19 | 1988-06-29 | Abbott Laboratories | Methods and materials for HBeAg production |
DE10299017I2 (de) | 1987-06-22 | 2005-05-25 | Medeva Holdings Bv | Hepatitis-B-Oberfl{chenantigen enthaltendes Peptid. |
EP0311228A3 (en) * | 1987-10-09 | 1990-05-02 | Repligen Corporation | Recombinant polypeptides and their uses, including assay for aids virus |
DE68907996T2 (de) * | 1988-05-11 | 1994-01-05 | Abbott Lab | Verfahren zur Erhöhung der Spezifizität in kompetitiven Immuntests. |
US5122449A (en) * | 1988-10-07 | 1992-06-16 | Eastman Kodak Company | Use of a protease in the extraction of chlamydial, gonococcal and herpes antigens |
US5501948A (en) * | 1989-02-06 | 1996-03-26 | Imclone Systems Incorporated | Stabilized hepatitis B e antigen suitable for immunoassays |
CA2009270A1 (en) * | 1989-02-06 | 1990-08-06 | Daniel J. Hicklin | Stabilized hepatitis e antigen suitable for immunoassays |
EP0491077A1 (en) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | A composition used as a therapeutic agent against chronic viral hepatic diseases |
DE4107612A1 (de) | 1991-03-09 | 1992-09-10 | Behringwerke Ag | Rekombinante proteine mit der immunreaktivitaet des hepatitis b virus e antigens (hbeag), verfahren zu ihrer herstellung und ihre verwendung in immunoassays und impfstoffen |
JP3225468B2 (ja) * | 1992-08-28 | 2001-11-05 | ダイナボット株式会社 | 抗体測定用試薬 |
WO1997035204A1 (en) * | 1996-03-19 | 1997-09-25 | Akzo Nobel N.V. | Method for predicting the outcome of hepatitis b infection |
US6887464B1 (en) * | 1999-02-02 | 2005-05-03 | Biocache Pharmaceuticals, Inc. | Advanced antigen presentation platform |
CA2419046C (en) * | 2000-08-11 | 2007-10-02 | Advanced Life Science Institute, Inc. | Method for detecting or measuring hbv |
EP1311860A2 (en) * | 2000-08-21 | 2003-05-21 | Queen's University At Kingston | Methods and kits for separation and detection of proteins in biological samples |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3636191A (en) * | 1969-10-08 | 1972-01-18 | Cancer Res Inst | Vaccine against viral hepatitis and process |
BE796781A (nl) * | 1973-03-15 | 1973-09-17 | Den Bosch Maurits R M J Van | Verbeterde armband of dergelijke |
JPS50312A (es) * | 1973-05-09 | 1975-01-06 | ||
FR2303562A1 (fr) * | 1975-03-14 | 1976-10-08 | Community Blood Council Greate | Nouvelle preparation d'antigene utilisable comme vaccin |
US4164565A (en) * | 1975-03-14 | 1979-08-14 | New York Blood Center, Inc. | Vaccine for active immunization containing hepatitis B surface antigen and associated antigen |
US4017360A (en) * | 1975-05-14 | 1977-04-12 | Merck & Co., Inc. | Method for purifying hepatitis B antigen |
US4021540A (en) * | 1975-07-28 | 1977-05-03 | Ortho Diagnostics Inc. | Preparation of a hepatitis B immune globulin and use thereof as a prophylactic material |
SE420977B (sv) * | 1976-03-18 | 1981-11-16 | Kabi Ab | Forfarande for rening och isolering av hepatitvirus for vaccinframstellning |
US4102996A (en) * | 1977-04-20 | 1978-07-25 | Merck & Co., Inc. | Method of preparing hepatitis B core antigen |
FR2398504A1 (fr) * | 1977-07-29 | 1979-02-23 | Tours Inst Virologie | Culture de virus de l'hepatite a, in vitro. application a la production d'un antigene reactif, d'immunserums specifiques et de vaccins contre l'hepatite a |
US4197361A (en) * | 1977-08-23 | 1980-04-08 | Warner-Lambert | Fluorescent immunoassay sandwich technique for HBs Ag |
US4234564A (en) * | 1977-12-19 | 1980-11-18 | Merck & Co., Inc. | Hepatitis B core antigen composition |
FR2422685A1 (fr) * | 1978-04-14 | 1979-11-09 | Pasteur Institut | Vecteurs, derives du bacteriophage lambda, permettant l'insertion et l'expression d'un gene, procaryote ou eucaryote, sous le controle du promoteur et de l'operateur de l'operon lactose de la bacterie escherichia coli |
ZA792485B (en) * | 1978-06-07 | 1980-06-25 | New York Blood Center Inc | Vaccine for active immunization containing hepatitis b surface and/or e-antigens |
US4164566A (en) * | 1978-08-17 | 1979-08-14 | Merck & Co., Inc. | Hepatitis a virus cell culture in vitro |
US4162192A (en) * | 1978-09-28 | 1979-07-24 | Juridical Foundation | Method for purification of HBs antigen |
US4204989A (en) * | 1978-12-13 | 1980-05-27 | Merck & Co., Inc. | Isolation of hepatitis B e antigen |
FR2444713A1 (fr) * | 1978-12-18 | 1980-07-18 | Pasteur Institut | Procede de production d'un adn comprenant le genome du virus de l'hepatite b et vecteur le comportant |
NO794196L (no) * | 1978-12-22 | 1980-06-24 | Biogen Nv | Fremgangsmaate ved fremstilling av et rekombinert dna molekyl |
US4301250A (en) * | 1979-11-02 | 1981-11-17 | Merck & Co., Inc. | Method of producing hepatitis B surface antigen |
US4617260A (en) * | 1981-02-27 | 1986-10-14 | Merck & Co., Inc. | RIA assay for HBcAg |
-
1982
- 1982-08-20 AU AU87465/82A patent/AU8746582A/en not_active Abandoned
- 1982-08-26 EP EP82304515A patent/EP0075395A3/en not_active Ceased
- 1982-08-30 JP JP57149377A patent/JPS5852228A/ja active Pending
- 1982-08-30 ZA ZA826310A patent/ZA826310B/xx unknown
- 1982-08-31 DK DK389682A patent/DK389682A/da unknown
- 1982-09-01 ES ES515418A patent/ES8404186A1/es not_active Expired
- 1982-09-01 FI FI823021A patent/FI823021L/fi not_active Application Discontinuation
- 1982-09-02 CA CA000410700A patent/CA1209502A/en not_active Expired
- 1982-09-02 US US06/414,439 patent/US4563423A/en not_active Expired - Lifetime
-
1985
- 1985-10-04 US US06/784,115 patent/US4758507A/en not_active Expired - Fee Related
-
1992
- 1992-09-30 JP JP4283454A patent/JPH06194369A/ja active Pending
- 1992-09-30 JP JP4283453A patent/JPH06194368A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US4758507A (en) | 1988-07-19 |
JPH06194369A (ja) | 1994-07-15 |
ES515418A0 (es) | 1984-04-16 |
DK389682A (da) | 1983-03-03 |
AU8746582A (en) | 1983-03-10 |
EP0075395A3 (en) | 1984-03-07 |
JPH06194368A (ja) | 1994-07-15 |
EP0075395A2 (en) | 1983-03-30 |
US4563423A (en) | 1986-01-07 |
ZA826310B (en) | 1983-07-27 |
CA1209502A (en) | 1986-08-12 |
JPS5852228A (ja) | 1983-03-28 |
FI823021A0 (fi) | 1982-09-01 |
FI823021L (fi) | 1983-03-03 |
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