ES8403855A1 - "procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo". - Google Patents
"procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo".Info
- Publication number
- ES8403855A1 ES8403855A1 ES516723A ES516723A ES8403855A1 ES 8403855 A1 ES8403855 A1 ES 8403855A1 ES 516723 A ES516723 A ES 516723A ES 516723 A ES516723 A ES 516723A ES 8403855 A1 ES8403855 A1 ES 8403855A1
- Authority
- ES
- Spain
- Prior art keywords
- phenethylamino
- dichlorophenoxy
- dimethoxy
- beta
- propan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-(2,4-DICLOROFENOXI)- 3-(3,4-DIMETOXI-B-FENETILAMINO)-PROPANOL-2 RACEMICO Y OPTICAMENTE ACTIVO, ASI COMO DE SUS ESTERES Y SALES DE ADICION DE ACIDO, DE FORMULA (I).CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN LAS QUE X ES EL GRUPO AMINO-NH2 O UN HALOGENO, TAL COMO CLORO, Y R PUEDE SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 200JC.ESTOS COMPUESTOS TIENEN APLICACIONESFARMACOLOGICAS COMO AGENTE ANTIHIPERTENSIVO, ANTIARRITMICO Y CARDIOPROTECTOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DD81234259A DD204248A1 (de) | 1981-10-21 | 1981-10-21 | Verfahren zur herstellung von 1-(2,4-dichlorphenoxy)-3 (3,4-dimethoxy-beta-phenethylamino)-propanol-(2) |
Publications (2)
Publication Number | Publication Date |
---|---|
ES516723A0 ES516723A0 (es) | 1984-05-01 |
ES8403855A1 true ES8403855A1 (es) | 1984-05-01 |
Family
ID=5534243
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES516723A Expired ES8403855A1 (es) | 1981-10-21 | 1982-10-21 | "procedimiento para la preparacion de 1-(2,4-diclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo". |
ES529193A Expired ES8500617A1 (es) | 1981-10-21 | 1984-01-26 | Procedimiento para la preparacion de 1-(2, 4-diclorofenoxi)-3-(3, 4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo |
ES529192A Expired ES8407317A1 (es) | 1981-10-21 | 1984-01-26 | Procedimiento para la preparacion de 1-(2,4-diciclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-2 racemico y op- ticamente activo. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529193A Expired ES8500617A1 (es) | 1981-10-21 | 1984-01-26 | Procedimiento para la preparacion de 1-(2, 4-diclorofenoxi)-3-(3, 4-dimetoxi-b-fenetilamino)-propanol-(2) racemico y opticamente activo |
ES529192A Expired ES8407317A1 (es) | 1981-10-21 | 1984-01-26 | Procedimiento para la preparacion de 1-(2,4-diciclorofenoxi)-3-(3,4-dimetoxi-b-fenetilamino)-propanol-2 racemico y op- ticamente activo. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0086256B1 (es) |
JP (1) | JPS58131946A (es) |
AT (1) | ATE15031T1 (es) |
BG (1) | BG40396A1 (es) |
CS (1) | CS247552B1 (es) |
DD (1) | DD204248A1 (es) |
DE (1) | DE3265640D1 (es) |
DK (1) | DK154209C (es) |
ES (3) | ES8403855A1 (es) |
FI (1) | FI79296C (es) |
HU (1) | HU190994B (es) |
NO (1) | NO155052C (es) |
SU (1) | SU1507763A1 (es) |
YU (3) | YU43530B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62156230A (ja) * | 1985-12-27 | 1987-07-11 | Nippon Steel Corp | 帯状物の蛇行修正方法 |
-
1981
- 1981-10-21 DD DD81234259A patent/DD204248A1/de unknown
-
1982
- 1982-10-18 FI FI823563A patent/FI79296C/fi not_active IP Right Cessation
- 1982-10-18 EP EP82109607A patent/EP0086256B1/de not_active Expired
- 1982-10-18 AT AT82109607T patent/ATE15031T1/de not_active IP Right Cessation
- 1982-10-18 DE DE8282109607T patent/DE3265640D1/de not_active Expired
- 1982-10-19 NO NO823477A patent/NO155052C/no unknown
- 1982-10-20 YU YU2356/82A patent/YU43530B/xx unknown
- 1982-10-20 DK DK464982A patent/DK154209C/da not_active IP Right Cessation
- 1982-10-21 JP JP57185341A patent/JPS58131946A/ja active Granted
- 1982-10-21 ES ES516723A patent/ES8403855A1/es not_active Expired
- 1982-10-21 BG BG8258364A patent/BG40396A1/xx unknown
- 1982-10-21 CS CS827489A patent/CS247552B1/cs unknown
- 1982-10-21 SU SU823506785A patent/SU1507763A1/ru active
- 1982-10-21 HU HU823371A patent/HU190994B/hu not_active IP Right Cessation
-
1984
- 1984-01-26 ES ES529193A patent/ES8500617A1/es not_active Expired
- 1984-01-26 ES ES529192A patent/ES8407317A1/es not_active Expired
-
1985
- 1985-04-22 YU YU00666/85A patent/YU66685A/xx unknown
- 1985-04-22 YU YU00667/85A patent/YU66785A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FI79296C (fi) | 1989-12-11 |
ES529193A0 (es) | 1984-11-16 |
JPS58131946A (ja) | 1983-08-06 |
ES529192A0 (es) | 1984-10-01 |
YU66785A (en) | 1985-10-31 |
SU1507763A1 (ru) | 1989-09-15 |
HU190994B (en) | 1986-12-28 |
YU43530B (en) | 1989-08-31 |
DD204248A1 (de) | 1983-11-23 |
ES8407317A1 (es) | 1984-10-01 |
CS247552B1 (en) | 1987-01-15 |
DK154209B (da) | 1988-10-24 |
NO155052C (no) | 1987-02-04 |
JPS6311347B2 (es) | 1988-03-14 |
EP0086256B1 (de) | 1985-08-21 |
ES516723A0 (es) | 1984-05-01 |
DE3265640D1 (en) | 1985-09-26 |
FI79296B (fi) | 1989-08-31 |
EP0086256A1 (de) | 1983-08-24 |
FI823563L (fi) | 1983-04-22 |
ATE15031T1 (de) | 1985-09-15 |
NO823477L (no) | 1983-04-22 |
FI823563A0 (fi) | 1982-10-18 |
YU66685A (en) | 1985-10-31 |
BG40396A1 (en) | 1986-12-15 |
NO155052B (no) | 1986-10-27 |
ES8500617A1 (es) | 1984-11-16 |
DK154209C (da) | 1989-03-20 |
YU235682A (en) | 1985-08-31 |
DK464982A (da) | 1983-04-22 |
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