ES8404348A1 - Un procedimiento para la preparacion de agentes antifungicos triazolicos. - Google Patents
Un procedimiento para la preparacion de agentes antifungicos triazolicos.Info
- Publication number
- ES8404348A1 ES8404348A1 ES520794A ES520794A ES8404348A1 ES 8404348 A1 ES8404348 A1 ES 8404348A1 ES 520794 A ES520794 A ES 520794A ES 520794 A ES520794 A ES 520794A ES 8404348 A1 ES8404348 A1 ES 8404348A1
- Authority
- ES
- Spain
- Prior art keywords
- processes
- pharmaceutical compositions
- compositions containing
- preparation
- antifungal agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE AGENTES ANTIFUNGICOS TRIAZOLICOS, DE FORMULA GENERAL (I) O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN LA QUE Q ES UN GRUPO FACILMENTE SALIENTE, CON 1,2,4-TRIAZOL O CON UNA SAL DEL MISMO. OPCIONALMENTE EL PRODUCTO OBTENIDO PUEDE CONVERTIRSE EN UNA SAL FARMACEUTICAMENTE ACEPTABLE.DE APLICACION EN EL TRATAMIENTO DE INFECCIONES FUNGICAS EN LOS ANIMALES, INCLUIDOS LOS HUMANOS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8117379 | 1981-06-06 | ||
GB8131370 | 1981-10-17 | ||
GB8206329 | 1982-03-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES520794A0 ES520794A0 (es) | 1984-05-01 |
ES8404348A1 true ES8404348A1 (es) | 1984-05-01 |
Family
ID=27261198
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512882A Granted ES512882A0 (es) | 1981-06-06 | 1982-06-04 | Un procedimiento para la preparacion de agentes antifugicos triazolicos. |
ES520794A Expired ES8404348A1 (es) | 1981-06-06 | 1983-03-18 | Un procedimiento para la preparacion de agentes antifungicos triazolicos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512882A Granted ES512882A0 (es) | 1981-06-06 | 1982-06-04 | Un procedimiento para la preparacion de agentes antifugicos triazolicos. |
Country Status (27)
Country | Link |
---|---|
US (1) | US4404216A (es) |
EP (1) | EP0069442B1 (es) |
KR (1) | KR850001132B1 (es) |
AU (1) | AU529987B2 (es) |
CA (1) | CA1181076A (es) |
DE (1) | DE3262386D1 (es) |
DK (1) | DK149849C (es) |
EG (1) | EG17222A (es) |
ES (2) | ES512882A0 (es) |
FI (1) | FI71134C (es) |
GR (1) | GR76491B (es) |
HK (1) | HK8488A (es) |
HU (1) | HU189143B (es) |
IE (1) | IE53144B1 (es) |
IL (1) | IL65963A (es) |
IN (1) | IN158113B (es) |
LU (1) | LU88329I2 (es) |
MX (1) | MX7119E (es) |
MY (1) | MY8800094A (es) |
NL (1) | NL930061I2 (es) |
NO (2) | NO156128C (es) |
NZ (1) | NZ200864A (es) |
PH (1) | PH18015A (es) |
PL (1) | PL130909B1 (es) |
PT (1) | PT75017B (es) |
SG (1) | SG80887G (es) |
YU (1) | YU42770B (es) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5395942A (en) * | 1980-06-02 | 1995-03-07 | Zeneca Limited | Heterocyclic compounds |
US5466821A (en) * | 1981-03-18 | 1995-11-14 | Zeneca Limited | Heterocyclic compounds |
DE3218130A1 (de) * | 1982-05-14 | 1983-11-17 | Basf Ag, 6700 Ludwigshafen | Azolylmethyloxirane, verfahren zu ihrer herstellung und diese enthaltende fungizide |
US4510148A (en) * | 1982-06-12 | 1985-04-09 | Pfizer Inc. | 2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents |
US4466974A (en) * | 1982-11-16 | 1984-08-21 | Pfizer Inc. | Bistriazole antifungal agents |
GB8302500D0 (en) * | 1983-01-29 | 1983-03-02 | Pfizer Ltd | Antifungal agents |
GB8304282D0 (en) * | 1983-02-16 | 1983-03-23 | Pfizer Ltd | Antifungal agents |
GB8305377D0 (en) * | 1983-02-25 | 1983-03-30 | Pfizer Ltd | Antifungal agents |
DE3307217A1 (de) * | 1983-03-02 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Substituierte 1,3-diazolyl-2-propanole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel |
DE3307216A1 (de) * | 1983-03-02 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Fungizide mittel |
DE3307218A1 (de) * | 1983-03-02 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Substituierte diazolylalkyl-carbinole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel |
GB8306351D0 (en) * | 1983-03-08 | 1983-04-13 | Ici Plc | Azole fungicides |
DK159205C (da) * | 1983-03-16 | 1991-03-04 | Pfizer | Bis(triazol)alkanol-forbindelser, anvendelse af disse, farmaceutiske praeparater og landbrugsfungicider indeholdende disse og fremgangsmaade til behandling af planter eller froe, som har en svampeinfektion |
US4992454A (en) * | 1983-03-16 | 1991-02-12 | Pfizer Inc. | Antifungal 1,3-bis (1H-1,2,4-triazol-1-yl)-2-aryl butan-2-ols and derivatives thereof |
DE3313073A1 (de) * | 1983-04-12 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | 1-azolyl-3-pyrazolyl-2-propanol-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide |
GB8313235D0 (en) * | 1983-05-13 | 1983-06-22 | Pfizer Ltd | Antifungal agents |
US4482564A (en) * | 1983-06-03 | 1984-11-13 | Schering Corporation | Triazolyl-substituted propane derivatives |
DE3332415A1 (de) * | 1983-09-08 | 1985-03-28 | Messerschmitt-Bölkow-Blohm GmbH, 8012 Ottobrunn | Steuerbares stroemungsumlenksystem |
USH672H (en) | 1986-12-31 | 1989-09-05 | E. R. Squibb & Sons, Inc. | Stable antifungal capsule formulation |
US4916134A (en) * | 1987-03-25 | 1990-04-10 | Janssen Pharmacuetica N.V. | 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]me]phenyl]-1-piperazinyl]phenyl]triazolones |
GB9002375D0 (en) * | 1990-02-02 | 1990-04-04 | Pfizer Ltd | Triazole antifungal agents |
DE4134125C2 (de) * | 1991-10-15 | 1995-02-02 | Mack Chem Pharm | Triazol-Derivate enthaltende pharmazeutische Zusammensetzungen zur rektalen Applikation |
TW212798B (es) * | 1991-11-25 | 1993-09-11 | Takeda Pharm Industry Co Ltd | |
CA2102518A1 (en) * | 1992-03-04 | 1993-09-05 | Vladimir Z. Gurevich | Antifungal agents |
ES2040181B1 (es) * | 1992-03-30 | 1994-05-16 | Uriach & Cia Sa J | Procedimiento para la obtencion de nuevas dihidropiridinas. |
IL105200A (en) * | 1993-03-29 | 1997-03-18 | Teva Pharma | Regiospecific processes for the preparation of 1, 3-bis (1, 2, 4-triazol-1-yl)-propan- 2-ol derivatives |
CA2106032C (en) * | 1993-09-13 | 1995-11-07 | Gamini Weeratunga | Methods for the manufacture of fluconazole and forms thereof, intermediates useful in the manufacture thereof, and combinations comprising fluconazole |
US6043064A (en) * | 1993-10-22 | 2000-03-28 | Bristol-Myers Squibb Company | Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof |
NZ270418A (en) | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
CA2139079C (en) * | 1994-12-23 | 1996-05-28 | K.S. Keshava Murthy | Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof |
CN1054853C (zh) * | 1995-01-11 | 2000-07-26 | 上海三维制药公司 | 氟康唑中间体1-[2-(2,4-二氟苯基)2,3-环氧丙基]-1h-1,2,4-三氮唑及其甲磺酸盐的制备方法 |
US6200992B1 (en) | 1995-06-07 | 2001-03-13 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
US5665751A (en) * | 1995-06-07 | 1997-09-09 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
US5770616A (en) * | 1995-06-07 | 1998-06-23 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
NZ272586A (en) * | 1995-07-17 | 1996-10-28 | Apotex Inc | Process for preparing fluconazole and triazolylepoxypropane precursors |
US5908855A (en) * | 1996-07-16 | 1999-06-01 | The Procter & Gamble Company | Compositions for treating viral infections |
GB9605705D0 (en) | 1996-03-19 | 1996-05-22 | Pfizer Ltd | Therapeutic agents |
TW436484B (en) * | 1996-04-24 | 2001-05-28 | Dev Center Biotechnology | 1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof |
DE19617282A1 (de) * | 1996-04-30 | 1997-11-06 | Bayer Ag | Triazolyl-mercaptide |
DE19617461A1 (de) | 1996-05-02 | 1997-11-06 | Bayer Ag | Acylmercapto-triazolyl-Derivate |
DE19619544A1 (de) | 1996-05-15 | 1997-11-20 | Bayer Ag | Triazolyl-Disulfide |
DE19620407A1 (de) * | 1996-05-21 | 1997-11-27 | Bayer Ag | Thiocyano-triazolyl-Derivate |
DE19620590A1 (de) * | 1996-05-22 | 1997-11-27 | Bayer Ag | Sulfonyl-mercapto-triazolyl-Derivate |
US5710280A (en) * | 1996-07-09 | 1998-01-20 | Development Center For Biotechnology | Preparation of fluconazole and pharmaceutically acceptable salts thereof |
NZ328607A (en) * | 1996-09-09 | 1999-08-30 | Hoffmann La Roche | Heterocyclically substituted n-benzyl-azolium derivatives and fungicidal compositions |
KR100194945B1 (ko) * | 1997-01-29 | 1999-06-15 | 서치영 | 플루코나졸의 제조방법 |
GR980100028A (el) * | 1998-01-15 | 1999-09-30 | Drug Research Hellas ����� | Φαρμακευτικα προιοντα για τοπικη χρηση που περιεχουν φλουκοναζολη σε συγκεντρωσεις μεταξυ 0,2% και 5% |
CN1081189C (zh) * | 1998-07-17 | 2002-03-20 | 国家医药管理局四川抗菌素工业研究所 | 唑醇类新衍生物及其制备方法和医药用途 |
IN191188B (es) | 2000-03-07 | 2003-10-04 | Ranbaxy Lab Ltd | |
KR100423666B1 (ko) * | 2001-02-07 | 2004-03-18 | 보령제약 주식회사 | 항진균 외용 제제 |
HUP0303249A3 (en) | 2001-02-22 | 2007-03-28 | Sankyo Co | Water-soluble triazole fungicide compounds and pharmaceutical compositions containing them |
CA2439310C (en) * | 2001-03-23 | 2009-09-29 | Richter Gedeon Vegyeszeti Gyar Rt. | Process for preparing fluconazole and its crystal modifications |
WO2002076426A2 (en) * | 2001-03-27 | 2002-10-03 | Galen (Chemicals) Limited | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
WO2003068142A2 (en) * | 2002-02-12 | 2003-08-21 | Fdc Limited | 1,2,4-triazol-1-yl-propan-2-ol derivatives as anti-fungal agents |
AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
US8404751B2 (en) * | 2002-09-27 | 2013-03-26 | Hallux, Inc. | Subunguicide, and method for treating onychomycosis |
US20050074494A1 (en) * | 2003-10-06 | 2005-04-07 | Xiu-Xiu Cheng | Itraconazole immediate release formulation |
GB0402491D0 (en) * | 2004-02-04 | 2004-03-10 | Pfizer Ltd | Medicaments |
US20050282878A1 (en) * | 2004-04-13 | 2005-12-22 | Batchu Chandrasekhar | Process for the purification of fluconazole |
US20060252940A1 (en) * | 2005-05-05 | 2006-11-09 | Sudhakar Valluri | Crystalline 1-[2-(2,4-difluorophenyl)-oxiranyl methyl]-1h-1,2,4-triazole |
EP1951705A4 (en) * | 2005-10-31 | 2010-12-15 | Dae Woong Pharma | NEW ANTIFUNGAL TRIAZOLE DERIVATIVES |
TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
KR100909953B1 (ko) * | 2007-06-15 | 2009-07-31 | 한국화학연구원 | 항진균 활성을 갖는 트라이아졸 유도체, 이의 제조방법 및이를 함유하는 약학 조성물 |
US20090062357A1 (en) * | 2007-08-29 | 2009-03-05 | Protia, Llc | Deuterium-enriched fluconazole |
JP2009286756A (ja) * | 2008-05-30 | 2009-12-10 | Fujifilm Finechemicals Co Ltd | トリアゾール誘導体またはその塩 |
KR100971371B1 (ko) | 2010-02-04 | 2010-07-20 | 동국제약 주식회사 | 신규한 중간체를 이용한 보리코나졸의 제조방법 |
WO2011101862A1 (en) | 2010-02-17 | 2011-08-25 | Fdc Limited | Stabilized fluconazole polymorph iii formulation |
US9309273B2 (en) * | 2011-12-11 | 2016-04-12 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
RU2015143995A (ru) | 2013-03-14 | 2017-04-20 | Халлюкс, Инк. | Способ лечения инфекций, заболеваний или расстройств ногтевого ложа |
BR102013027313B1 (pt) * | 2013-10-23 | 2019-06-18 | Iharabras S.A. Indústrias Químicas | Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso |
RU2538962C1 (ru) * | 2013-11-19 | 2015-01-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) | Противогрибковые соединения на основе производных 3,5,8-триоксабицикло[5.1.0]октана |
EA037521B1 (ru) | 2015-09-18 | 2021-04-07 | ВиПиЭс-3, ИНК. | Противогрибковые соединения и способы их получения |
EP3810777A4 (en) | 2018-06-21 | 2022-03-30 | Yumanity Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS |
CN111518041A (zh) * | 2020-04-24 | 2020-08-11 | 湖南复瑞生物医药技术有限责任公司 | 一种2’4’-二氟-2-[1-(1h-1,2,4-***基)]苯乙酮的制备方法 |
CN111454227A (zh) * | 2020-05-21 | 2020-07-28 | 湖南复瑞生物医药技术有限责任公司 | 一种西洛他唑中间体的制备方法 |
CN112137972A (zh) * | 2020-09-16 | 2020-12-29 | 石家庄四药有限公司 | 一种氟康唑片剂组合物、片剂及制备方法 |
KR102434209B1 (ko) * | 2022-01-28 | 2022-08-19 | 전기열 | 천연 오일을 함유한 발모촉진 및 탈모방지용 조성물 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2078719B (en) * | 1980-06-02 | 1984-04-26 | Ici Ltd | Heterocyclic compounds |
-
1982
- 1982-04-22 EP EP82302075A patent/EP0069442B1/en not_active Expired
- 1982-04-22 DE DE8282302075T patent/DE3262386D1/de not_active Expired
- 1982-05-28 IE IE1285/82A patent/IE53144B1/en active Protection Beyond IP Right Term
- 1982-05-31 HU HU821755A patent/HU189143B/hu unknown
- 1982-06-01 US US06/383,866 patent/US4404216A/en not_active Expired - Lifetime
- 1982-06-02 PH PH27392A patent/PH18015A/en unknown
- 1982-06-03 KR KR8202493A patent/KR850001132B1/ko active
- 1982-06-03 IN IN427/DEL/82A patent/IN158113B/en unknown
- 1982-06-03 IL IL65963A patent/IL65963A/xx not_active IP Right Cessation
- 1982-06-03 PL PL1982236740A patent/PL130909B1/pl unknown
- 1982-06-04 MX MX8210108U patent/MX7119E/es unknown
- 1982-06-04 PT PT75017A patent/PT75017B/pt unknown
- 1982-06-04 GR GR68354A patent/GR76491B/el unknown
- 1982-06-04 FI FI822005A patent/FI71134C/fi not_active IP Right Cessation
- 1982-06-04 DK DK252282A patent/DK149849C/da not_active IP Right Cessation
- 1982-06-04 CA CA000404514A patent/CA1181076A/en not_active Expired
- 1982-06-04 NZ NZ200864A patent/NZ200864A/en unknown
- 1982-06-04 YU YU1195/82A patent/YU42770B/xx unknown
- 1982-06-04 AU AU84484/82A patent/AU529987B2/en not_active Expired
- 1982-06-04 ES ES512882A patent/ES512882A0/es active Granted
- 1982-06-04 NO NO821886A patent/NO156128C/no not_active IP Right Cessation
- 1982-06-05 EG EG319/82A patent/EG17222A/xx active
-
1983
- 1983-03-18 ES ES520794A patent/ES8404348A1/es not_active Expired
-
1987
- 1987-10-08 SG SG808/87A patent/SG80887G/en unknown
-
1988
- 1988-01-28 HK HK84/88A patent/HK8488A/xx not_active IP Right Cessation
- 1988-12-30 MY MY94/88A patent/MY8800094A/xx unknown
-
1993
- 1993-06-11 NL NL930061C patent/NL930061I2/nl unknown
- 1993-06-24 LU LU88329C patent/LU88329I2/fr unknown
-
1994
- 1994-11-02 NO NO1994019C patent/NO1994019I1/no unknown
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Effective date: 20040221 |