ES8308927A1 - Procedimiento para la preparacion de 3-(5'- ribonucleotidos) de compuestos del tipo de lincomicina y clindamicina. - Google Patents
Procedimiento para la preparacion de 3-(5'- ribonucleotidos) de compuestos del tipo de lincomicina y clindamicina.Info
- Publication number
- ES8308927A1 ES8308927A1 ES511499A ES511499A ES8308927A1 ES 8308927 A1 ES8308927 A1 ES 8308927A1 ES 511499 A ES511499 A ES 511499A ES 511499 A ES511499 A ES 511499A ES 8308927 A1 ES8308927 A1 ES 8308927A1
- Authority
- ES
- Spain
- Prior art keywords
- lincomycin
- ribonucleotides
- lincosaminide
- halomethyl
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 3-(5 -RIBONUCLEOTIDOS) DE COMPUESTOS DEL TIPO DE LINCOMICINA Y CLINDAMICINA. SE CULTIVA STREPTOMYCES ROCHEI NRRL 3533 EN UN MEDIO ACUOSO CONTENIENDO NUTRIENTES Y EN PRESENCIA DE COMPUESTOS (I). R<1 ES HIDROGENO, ALQUILO, CICLO-ALQUILO, OXIGENO SUSTITUIDO, NITROGENO SUSTITUIDO, HALOGENO, FENILO, FENILO SUSTITUIDO Y OTROS; N ES UN ENTERO CON VALOR DE 1 A 8 INCLUSIVE; R<4 Y R<5 SON HIDROGENO, O ALQUILO DE 1 A 8 ATOMOS DE CARBONO; R<3 SE SELECCIONA DE ENTRE H, CH<3, C<2H<5, CH<2-CH<2-OH; Y SE SELECCIONA DE ENTRE 7(S)-HALO Y 7(R)-HALO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/255,542 US4383109A (en) | 1981-04-20 | 1981-04-20 | Lincomycin nucleotides |
US06/255,541 US4368193A (en) | 1981-04-20 | 1981-04-20 | Process for treating malaria |
Publications (2)
Publication Number | Publication Date |
---|---|
ES511499A0 ES511499A0 (es) | 1983-10-01 |
ES8308927A1 true ES8308927A1 (es) | 1983-10-01 |
Family
ID=26944757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511499A Expired ES8308927A1 (es) | 1981-04-20 | 1982-04-17 | Procedimiento para la preparacion de 3-(5'- ribonucleotidos) de compuestos del tipo de lincomicina y clindamicina. |
Country Status (15)
Country | Link |
---|---|
KR (1) | KR880002416B1 (es) |
AU (1) | AU545748B2 (es) |
CA (1) | CA1163938A (es) |
CH (1) | CH653037A5 (es) |
DE (1) | DE3213921A1 (es) |
ES (1) | ES8308927A1 (es) |
FR (1) | FR2504142B1 (es) |
GB (1) | GB2097002B (es) |
HU (1) | HU191085B (es) |
IL (1) | IL65385A (es) |
IT (1) | IT1151719B (es) |
NL (1) | NL8201595A (es) |
PL (1) | PL133485B1 (es) |
SE (1) | SE459861B (es) |
SU (1) | SU1303036A3 (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3671647A (en) * | 1971-03-24 | 1972-06-20 | Upjohn Co | Lincomycin 3-nucleotides and the salts thereof |
-
1982
- 1982-03-19 CA CA000398814A patent/CA1163938A/en not_active Expired
- 1982-03-25 GB GB8208830A patent/GB2097002B/en not_active Expired
- 1982-03-26 AU AU81988/82A patent/AU545748B2/en not_active Ceased
- 1982-03-30 IL IL65385A patent/IL65385A/xx unknown
- 1982-04-15 DE DE19823213921 patent/DE3213921A1/de not_active Ceased
- 1982-04-16 NL NL8201595A patent/NL8201595A/nl not_active Application Discontinuation
- 1982-04-17 ES ES511499A patent/ES8308927A1/es not_active Expired
- 1982-04-17 KR KR8201712A patent/KR880002416B1/ko active
- 1982-04-19 SU SU823430749A patent/SU1303036A3/ru active
- 1982-04-19 FR FR828206685A patent/FR2504142B1/fr not_active Expired
- 1982-04-19 IT IT20810/82A patent/IT1151719B/it active
- 1982-04-19 SE SE8202433A patent/SE459861B/sv not_active IP Right Cessation
- 1982-04-20 CH CH2386/82A patent/CH653037A5/de not_active IP Right Cessation
- 1982-04-20 PL PL1982236043A patent/PL133485B1/pl unknown
- 1982-04-20 HU HU821214A patent/HU191085B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU545748B2 (en) | 1985-08-01 |
GB2097002B (en) | 1985-06-19 |
KR880002416B1 (ko) | 1988-11-08 |
SE459861B (sv) | 1989-08-14 |
PL236043A1 (es) | 1982-11-08 |
ES511499A0 (es) | 1983-10-01 |
CA1163938A (en) | 1984-03-20 |
DE3213921A1 (de) | 1983-01-05 |
IT1151719B (it) | 1986-12-24 |
AU8198882A (en) | 1982-10-28 |
SU1303036A3 (ru) | 1987-04-07 |
NL8201595A (nl) | 1982-11-16 |
CH653037A5 (de) | 1985-12-13 |
IL65385A (en) | 1985-10-31 |
FR2504142A1 (fr) | 1982-10-22 |
HU191085B (en) | 1987-01-28 |
IT8220810A0 (it) | 1982-04-19 |
GB2097002A (en) | 1982-10-27 |
FR2504142B1 (fr) | 1985-07-26 |
KR830010195A (ko) | 1983-12-26 |
PL133485B1 (en) | 1985-06-29 |
IL65385A0 (en) | 1982-05-31 |
SE8202433L (sv) | 1982-10-21 |
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