ES8303091A1 - Un procedimiento para la preparacion de una nueva formulacion de bacampicilina. - Google Patents
Un procedimiento para la preparacion de una nueva formulacion de bacampicilina.Info
- Publication number
- ES8303091A1 ES8303091A1 ES504905A ES504905A ES8303091A1 ES 8303091 A1 ES8303091 A1 ES 8303091A1 ES 504905 A ES504905 A ES 504905A ES 504905 A ES504905 A ES 504905A ES 8303091 A1 ES8303091 A1 ES 8303091A1
- Authority
- ES
- Spain
- Prior art keywords
- suspension
- acid addition
- addition salt
- bacampicillin
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE FORMULACIONES DE BACAMPICILINA, CONSTITUIDA POR UN POLVO, QUE POR ADICION DE AGUA FORMA UNA SUSPENSION FARMACEUTICA DE MOCROCAPSULAS. CONSISTE EN FLUIDIFICAR EN UN LECHO UNA SAL DE ADICION DE ACIDO DE BACAMPICILINA SOLUBLE EN AGUA; PULVERIZAR SOBRE EL LECHO UNA DISOLUCION O SUSPENSION CONSTITUIDA POR CELULOSA Y POR UN MATERIAL DE CARGA, SOLUBLE EN AGUA O PERMEABLE A ELLA; Y COMBINAR LAS MICROCAPSULAS ASI FORMADAS CON INGREDIENTES, TALES QUE EL PH DEL MEDIO SUSPENSOR ACUOSO EN LA SUSPENSION NO ES INFERIOR A 6,9. ESTAS FORMULACIONES TIENEN APLICACIONES EN FARMACOLOGIA PARA LA ADMINISTRACION ORAL DE DOSIS MULTIPLES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/180,537 US4321253A (en) | 1980-08-22 | 1980-08-22 | Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration |
Publications (2)
Publication Number | Publication Date |
---|---|
ES504905A0 ES504905A0 (es) | 1983-02-01 |
ES8303091A1 true ES8303091A1 (es) | 1983-02-01 |
Family
ID=22660812
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504905A Expired ES8303091A1 (es) | 1980-08-22 | 1981-08-21 | Un procedimiento para la preparacion de una nueva formulacion de bacampicilina. |
Country Status (41)
Country | Link |
---|---|
US (1) | US4321253A (es) |
JP (1) | JPS5775986A (es) |
KR (1) | KR860000513B1 (es) |
AR (1) | AR227201A1 (es) |
AT (1) | AT370994B (es) |
AU (1) | AU529965B2 (es) |
BE (1) | BE890028A (es) |
BG (1) | BG42000A3 (es) |
CA (1) | CA1137414A (es) |
CH (1) | CH650674A5 (es) |
CS (1) | CS225845B2 (es) |
DD (1) | DD201644A5 (es) |
DE (1) | DE3132614C2 (es) |
DK (1) | DK158971C (es) |
DZ (1) | DZ315A1 (es) |
ES (1) | ES8303091A1 (es) |
FI (1) | FI72647C (es) |
FR (1) | FR2488798A1 (es) |
GB (1) | GB2082539B (es) |
GR (1) | GR74983B (es) |
HK (1) | HK43786A (es) |
HU (1) | HU188679B (es) |
IE (1) | IE51506B1 (es) |
IL (1) | IL63617A (es) |
IN (1) | IN156538B (es) |
IT (1) | IT1138161B (es) |
KE (1) | KE3626A (es) |
LU (1) | LU83572A1 (es) |
MX (1) | MX5731A (es) |
MY (1) | MY8600597A (es) |
NL (1) | NL191978C (es) |
NO (1) | NO154821C (es) |
NZ (1) | NZ198106A (es) |
PH (1) | PH17125A (es) |
PL (1) | PL232141A1 (es) |
PT (1) | PT73555B (es) |
RO (1) | RO82679B (es) |
SE (1) | SE448819B (es) |
SU (1) | SU1364226A3 (es) |
YU (1) | YU43985B (es) |
ZA (1) | ZA815793B (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE48715B1 (en) * | 1978-12-22 | 1985-05-01 | Elan Corp Plc | New galencial forms for administration of medicaments by oral route,with programmed release and processes for preparing same |
SE8103843L (sv) * | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
US4994260A (en) * | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
SE8203953D0 (sv) * | 1982-06-24 | 1982-06-24 | Astra Laekemedel Ab | Pharmaceutical mixture |
US4508702A (en) * | 1982-06-14 | 1985-04-02 | Key Pharmaceuticals, Inc. | Sustained release aspirin |
EP0111560A4 (en) * | 1982-06-14 | 1987-02-03 | Key Pharma | ASPIRINE WITH CONTINUOUS LEVEL. |
DE3382392D1 (de) * | 1982-07-09 | 1991-10-02 | Key Pharma | Dosierungsart zur dauerhaften verabreichung von chinidin. |
US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
AU569277B2 (en) * | 1983-03-03 | 1988-01-28 | Dow Chemical Company, The | Aqueuos dispersion of water-insoluble organophilic cellulose ether for sustained release of active agents |
US4555399A (en) * | 1983-11-18 | 1985-11-26 | Key Pharmaceuticals, Inc. | Aspirin tablet |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
SE8405611D0 (sv) * | 1984-11-09 | 1984-11-09 | Astra Laekemedel Ab | Process for stabilization of bacampicillin hydrochloride |
US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
GB8628359D0 (en) * | 1986-11-27 | 1986-12-31 | Zyma Sa | Galenical formulation |
US4853229A (en) * | 1987-10-26 | 1989-08-01 | Alza Corporation | Method for adminstering tiny pills |
US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
US5599557A (en) * | 1992-04-30 | 1997-02-04 | Schering Corporation | Stable hydrated cephalosporin dry powder for oral suspension formulation |
US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
US6270804B1 (en) * | 1998-04-03 | 2001-08-07 | Biovail Technologies Ltd. | Sachet formulations |
IN191482B (es) * | 1999-03-19 | 2003-12-06 | Ranbaxy Lab Ltd | |
JP4711478B2 (ja) * | 1999-08-13 | 2011-06-29 | 旭化成ケミカルズ株式会社 | 味がマスクされた薬物 |
US20050037086A1 (en) * | 1999-11-19 | 2005-02-17 | Zycos Inc., A Delaware Corporation | Continuous-flow method for preparing microparticles |
SK8562002A3 (en) | 1999-12-23 | 2003-10-07 | Pfizer Prod Inc | Pharmaceutical compositions providing enhanced drug concentrations |
EP1118333A1 (en) * | 2000-01-18 | 2001-07-25 | Eurand International S.P.A. | Compositions with enhanced oral bioavailability |
US6551617B1 (en) | 2000-04-20 | 2003-04-22 | Bristol-Myers Squibb Company | Taste masking coating composition |
PT1276470E (pt) | 2000-04-20 | 2007-08-13 | Novartis Ag | Composição de revestimento para dissimular o sabor |
US20040142475A1 (en) * | 2000-06-02 | 2004-07-22 | Barman Shikha P. | Delivery systems for bioactive agents |
FR2822834B1 (fr) * | 2001-04-02 | 2005-02-25 | Flamel Tech Sa | Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation |
US20030096791A1 (en) * | 2001-05-31 | 2003-05-22 | Cima Labs Inc. | Taste masking of highly water-soluble drugs |
KR20030015655A (ko) * | 2001-08-17 | 2003-02-25 | 한미약품공업 주식회사 | 항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물 |
FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
AU2003246791A1 (en) * | 2002-04-09 | 2003-10-20 | Flamel Technologies | Oral suspension of amoxicillin capsules |
DE60325709D1 (de) | 2002-04-09 | 2009-02-26 | Flamel Tech Sa | Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen |
FR2842736B1 (fr) | 2002-07-26 | 2005-07-22 | Flamel Tech Sa | Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s) |
FR2842735B1 (fr) * | 2002-07-26 | 2006-01-06 | Flamel Tech Sa | Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os |
FR2843117B1 (fr) * | 2002-07-30 | 2004-10-15 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques |
US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
FR2860516B1 (fr) * | 2003-10-03 | 2006-01-13 | Flamel Tech Sa | Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques |
FR2862536B1 (fr) * | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques |
US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
FR2885526B1 (fr) * | 2005-05-13 | 2007-07-27 | Flamel Technologies Sa | Medicament oral a base d'inhibiteur de pompe a protons |
CN108601796B (zh) * | 2015-10-13 | 2020-03-03 | 技术防卫株式会社 | 胃肠道粘膜保护组合物 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3549746A (en) * | 1967-11-02 | 1970-12-22 | Bristol Myers Co | Antibiotic composition |
US3873521A (en) * | 1970-09-17 | 1975-03-25 | Astra Laekemedel Ab | Esters of {60 -amino penicillins |
ZA718014B (en) | 1970-12-23 | 1972-08-30 | Beecham Group Ltd | Pharmaceutical formulations |
US4016254A (en) * | 1972-05-19 | 1977-04-05 | Beecham Group Limited | Pharmaceutical formulations |
GB1455296A (en) * | 1973-05-24 | 1976-11-10 | Beecham Group Ltd | Veterinary treatment |
GB1479655A (en) | 1974-03-08 | 1977-07-13 | Beecham Group Ltd | Antibiotic preparations |
US4127647A (en) * | 1975-04-08 | 1978-11-28 | Meiji Seika Kaisha, Ltd. | Process for preparation of stable amorphous macrolide antibiotic solids |
JPS5840529B2 (ja) * | 1975-09-29 | 1983-09-06 | 明治製菓株式会社 | ケイコウヨウセイザイノセイホウ |
GB1561301A (en) * | 1976-01-02 | 1980-02-20 | Beecham Group Ltd | Orally administrable pharmaceutical composition |
ZA793935B (en) * | 1978-08-04 | 1980-07-30 | Beecham Group Ltd | Powders |
JPS57105316A (en) * | 1980-12-23 | 1982-06-30 | Hitachi Cable Ltd | Method of fitting heat-shrinkable tube |
-
1980
- 1980-08-22 US US06/180,537 patent/US4321253A/en not_active Expired - Lifetime
-
1981
- 1981-06-23 IN IN405/DEL/81A patent/IN156538B/en unknown
- 1981-07-08 DZ DZ816254A patent/DZ315A1/fr active
- 1981-07-08 RO RO104817A patent/RO82679B/ro unknown
- 1981-07-09 HU HU812005A patent/HU188679B/hu unknown
- 1981-07-09 SU SU813310057A patent/SU1364226A3/ru active
- 1981-07-10 CS CS815334A patent/CS225845B2/cs unknown
- 1981-07-10 BG BG052867A patent/BG42000A3/xx unknown
- 1981-07-10 PL PL23214181A patent/PL232141A1/xx unknown
- 1981-08-05 GB GB8123977A patent/GB2082539B/en not_active Expired
- 1981-08-14 CH CH5277/81A patent/CH650674A5/fr not_active IP Right Cessation
- 1981-08-18 DE DE3132614A patent/DE3132614C2/de not_active Expired
- 1981-08-19 AT AT0362781A patent/AT370994B/de not_active IP Right Cessation
- 1981-08-19 CA CA000384168A patent/CA1137414A/en not_active Expired
- 1981-08-19 AR AR286473A patent/AR227201A1/es active
- 1981-08-19 GR GR65819A patent/GR74983B/el unknown
- 1981-08-20 LU LU83572A patent/LU83572A1/fr unknown
- 1981-08-20 BE BE0/205725A patent/BE890028A/fr not_active IP Right Cessation
- 1981-08-20 IE IE1911/81A patent/IE51506B1/en not_active IP Right Cessation
- 1981-08-20 DD DD81232705A patent/DD201644A5/de not_active IP Right Cessation
- 1981-08-20 FI FI812574A patent/FI72647C/fi not_active IP Right Cessation
- 1981-08-20 PH PH26070A patent/PH17125A/en unknown
- 1981-08-20 IL IL63617A patent/IL63617A/xx not_active IP Right Cessation
- 1981-08-20 IT IT23587/81A patent/IT1138161B/it active
- 1981-08-20 NZ NZ198106A patent/NZ198106A/xx unknown
- 1981-08-20 YU YU2017/81A patent/YU43985B/xx unknown
- 1981-08-21 JP JP56131418A patent/JPS5775986A/ja active Granted
- 1981-08-21 ES ES504905A patent/ES8303091A1/es not_active Expired
- 1981-08-21 ZA ZA815793A patent/ZA815793B/xx unknown
- 1981-08-21 NL NL8103902A patent/NL191978C/xx not_active IP Right Cessation
- 1981-08-21 PT PT73555A patent/PT73555B/pt unknown
- 1981-08-21 AU AU74416/81A patent/AU529965B2/en not_active Expired
- 1981-08-21 DK DK372181A patent/DK158971C/da not_active IP Right Cessation
- 1981-08-21 NO NO812827A patent/NO154821C/no unknown
- 1981-08-21 KR KR1019810003057A patent/KR860000513B1/ko active
- 1981-08-21 SE SE8104974A patent/SE448819B/sv not_active IP Right Cessation
- 1981-08-21 FR FR8116074A patent/FR2488798A1/fr active Granted
- 1981-08-24 MX MX573181A patent/MX5731A/es unknown
-
1986
- 1986-04-04 KE KE3626A patent/KE3626A/xx unknown
- 1986-06-09 HK HK437/86A patent/HK43786A/xx not_active IP Right Cessation
- 1986-12-30 MY MY597/86A patent/MY8600597A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20100623 |