ES8200098A1 - Procedimiento para la obtencion de derivados de benzotiazol - Google Patents

Procedimiento para la obtencion de derivados de benzotiazol

Info

Publication number
ES8200098A1
ES8200098A1 ES490797A ES490797A ES8200098A1 ES 8200098 A1 ES8200098 A1 ES 8200098A1 ES 490797 A ES490797 A ES 490797A ES 490797 A ES490797 A ES 490797A ES 8200098 A1 ES8200098 A1 ES 8200098A1
Authority
ES
Spain
Prior art keywords
salts
compound
physiologically acceptable
preparation
formula see
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490797A
Other languages
English (en)
Other versions
ES490797A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Albert Rolland SA
Original Assignee
Laboratoires Albert Rolland SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Albert Rolland SA filed Critical Laboratoires Albert Rolland SA
Publication of ES490797A0 publication Critical patent/ES490797A0/es
Publication of ES8200098A1 publication Critical patent/ES8200098A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE BENZOTIAZOL. CONSISTE EN HACER REACCIONAR EL ACIDO BENZOICO O UN EQUIVALENTE REACCIONAL TAL COMO EL CLORURO DE ACIDO, ESTER O ALDEHIDO CORRESPONDIENTE, SOBRE UN COMPUESTO (I) O UN EQUIVALENTE DEL MISMO, TAL COMO UN DISULFURO CORRESPONDIENTE. EL ACIDO OBTENIDO SE PUEDE TRANSFORMAR EN UNA SAL O EN UN ESTER. LA ACCION DEL BENZOLDEHIDO SOBRE EL AMINOTIOL (I) TIENE LUGAR BIEN EN DISOLVENTE TAL COMO ES NITROBENCENO, BENCENO O EN UN DISOLVENTE BASICO TAL COMO PIRIDINA O QUINOLEINA. LAS SALES SE PUEDEN PREPARAR POR LA ACCION DE UNA CANTIDAD ESTEQUIMETRICA DEL ACIDO O BASE SOBRE LOS ACIDOS OBTENIDOS EN SOLUCION DE UN ALCOHOL, UNA CDTONA O UN ETER ALIFATICO.
ES490797A 1979-04-03 1980-04-01 Procedimiento para la obtencion de derivados de benzotiazol Expired ES8200098A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7908303A FR2453163A1 (fr) 1979-04-03 1979-04-03 Derives de benzothiazole, leur procede de preparation et leurs applications en therapeutique

Publications (2)

Publication Number Publication Date
ES490797A0 ES490797A0 (es) 1981-11-01
ES8200098A1 true ES8200098A1 (es) 1981-11-01

Family

ID=9223868

Family Applications (2)

Application Number Title Priority Date Filing Date
ES490797A Expired ES8200098A1 (es) 1979-04-03 1980-04-01 Procedimiento para la obtencion de derivados de benzotiazol
ES498313A Granted ES498313A0 (es) 1979-04-03 1980-12-11 Procedimiento para la separacion de un enantiomero del acido (fenil-2-benzotiazolil-6)-2 proponico dde la mezcla race- mica.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES498313A Granted ES498313A0 (es) 1979-04-03 1980-12-11 Procedimiento para la separacion de un enantiomero del acido (fenil-2-benzotiazolil-6)-2 proponico dde la mezcla race- mica.

Country Status (27)

Country Link
EP (1) EP0017543B1 (es)
JP (1) JPS55133367A (es)
AR (1) AR227884A1 (es)
AT (1) ATE4807T1 (es)
AU (1) AU530911B2 (es)
BE (1) BE882270A (es)
CA (1) CA1144556A (es)
DD (1) DD151448A5 (es)
DE (1) DE3065004D1 (es)
DK (1) DK134880A (es)
ES (2) ES8200098A1 (es)
FI (1) FI801023A (es)
FR (1) FR2453163A1 (es)
GR (1) GR67195B (es)
HU (1) HU178851B (es)
IL (1) IL59655A (es)
IT (1) IT8048308A0 (es)
MA (1) MA18772A1 (es)
NO (1) NO800946L (es)
NZ (1) NZ193337A (es)
OA (1) OA06504A (es)
PH (1) PH15451A (es)
PL (1) PL123701B1 (es)
PT (1) PT71035A (es)
SU (1) SU910120A3 (es)
YU (1) YU80780A (es)
ZA (1) ZA801574B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003066546A1 (fr) 2002-02-05 2003-08-14 Sumitomo Chemical Company, Limited Procede de production d'un compose biaryle
US9102614B2 (en) 2010-07-02 2015-08-11 Gilead Sciences, Inc. Naphth-2-ylacetic acid derivatives to treat AIDS
SG186821A1 (en) 2010-07-02 2013-02-28 Gilead Sciences Inc 2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds
PT2699558T (pt) * 2011-04-21 2016-12-29 Gilead Sciences Inc Compostos de benzotiazole e a sua utilização farmacêutica
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
US9284323B2 (en) 2012-01-04 2016-03-15 Gilead Sciences, Inc. Naphthalene acetic acid derivatives against HIV infection
NZ622769A (en) 2012-04-20 2017-06-30 Gilead Sciences Inc Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2145178C3 (de) * 1970-09-11 1975-12-11 Tokyo Tanabe Co., Ltd., Tokio 2-Phenyl-5-oder -6-benzothiazolylessigsäure-Verblndungen
US3895028A (en) * 1972-09-12 1975-07-15 Tokyo Tanabe Co Alpha-(2-phenylbenzothiazol-5-yl)propionic acid

Also Published As

Publication number Publication date
FI801023A (fi) 1980-10-04
JPS55133367A (en) 1980-10-17
ES490797A0 (es) 1981-11-01
NZ193337A (en) 1982-12-07
FR2453163B1 (es) 1982-07-02
DD151448A5 (de) 1981-10-21
AU5686480A (en) 1980-10-09
SU910120A3 (ru) 1982-02-28
IL59655A0 (en) 1980-06-30
FR2453163A1 (fr) 1980-10-31
NO800946L (no) 1980-10-06
ZA801574B (en) 1981-03-25
ATE4807T1 (de) 1983-10-15
PL223191A1 (es) 1981-01-30
IL59655A (en) 1983-05-15
GR67195B (es) 1981-06-24
OA06504A (fr) 1981-07-31
IT8048308A0 (it) 1980-04-01
ES8204989A1 (es) 1982-06-01
DK134880A (da) 1980-10-04
PT71035A (fr) 1980-04-01
AR227884A1 (es) 1982-12-30
CA1144556A (en) 1983-04-12
HU178851B (en) 1982-07-28
AU530911B2 (en) 1983-08-04
PL123701B1 (en) 1982-11-30
MA18772A1 (fr) 1980-10-01
BE882270A (fr) 1980-09-17
EP0017543B1 (fr) 1983-09-28
EP0017543A1 (fr) 1980-10-15
ES498313A0 (es) 1982-06-01
PH15451A (en) 1983-01-18
YU80780A (en) 1983-02-28
DE3065004D1 (en) 1983-11-03

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