ES8102570A1 - Procedimiento de preparar derivados dihalogenicos geminales - Google Patents

Procedimiento de preparar derivados dihalogenicos geminales

Info

Publication number
ES8102570A1
ES8102570A1 ES491896A ES491896A ES8102570A1 ES 8102570 A1 ES8102570 A1 ES 8102570A1 ES 491896 A ES491896 A ES 491896A ES 491896 A ES491896 A ES 491896A ES 8102570 A1 ES8102570 A1 ES 8102570A1
Authority
ES
Spain
Prior art keywords
compounds
pharmaceutical compositions
preparation
lower alkyl
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491896A
Other languages
English (en)
Other versions
ES491896A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of ES8102570A1 publication Critical patent/ES8102570A1/es
Publication of ES491896A0 publication Critical patent/ES491896A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00—Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DIHALOGENICOS GEMINALES DE FORMULA GENERAL, DONDE R REPRESENTA HIDROGENO, ALQUILO INFERIOR O ALCOXICARBONILO INFERIOR; R ELEVADO A 1 PUEDE SER HIDROGENO, ALQUILO INFERIOR, CARBOXI, UN GURPO ESTER O UN DERIVADO DEL MISMO, CINANO, FENILO O HALOGENOS; R ELEVADO A 2 PUEDE SER HIDROGENO, ALQUILO INFERIOR O FENILO; X PUEDE SER HALOGENO; N ES UN NUMERO ENTERO 0, 1 O 2. SE CARACTERIZA POR HACER REACCIONAR UN DERIVADO MONOHALOGENICO RACEMICO Y UN COMPUESTO RACEMICO CON UN COMPUESTO RACEMICO CON UN AGENTE HALOGENANTE. LA REACCION SE REALIZA A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 60GC Y CON UN DISOLVENTE INERTE ADECUADO A LA HALOGENACION. ESTOS DERIVADOS TIENEN PROPIEDADES ANTIALERGICAS Y ANTIASMATICAS. *FORMULA* Q
ES491896A 1979-05-11 1980-05-12 Procedimiento de preparar derivados dihalogenicos geminales Granted ES491896A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1932A HU179443B (en) 1979-05-11 1979-05-11 Process for producing substituted geminal dihalogeno-derivatives of pyrido-square bracket-1,2-a-square closed-pyrimidines,pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines and pyrimido-square bracket-1,2,-a-square bracket closed-asepines

Publications (2)

Publication Number Publication Date
ES8102570A1 true ES8102570A1 (es) 1981-02-16
ES491896A0 ES491896A0 (es) 1981-02-16

Family

ID=10994747

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491896A Granted ES491896A0 (es) 1979-05-11 1980-05-12 Procedimiento de preparar derivados dihalogenicos geminales

Country Status (24)

Country Link
JP (1) JPS5615286A (es)
AT (1) AT377261B (es)
BE (1) BE883217A (es)
CA (1) CA1141379A (es)
CH (1) CH646971A5 (es)
CS (1) CS241025B2 (es)
DD (1) DD150605A5 (es)
DE (1) DE3017564A1 (es)
DK (1) DK204680A (es)
ES (1) ES491896A0 (es)
FI (1) FI68825C (es)
FR (1) FR2456101A1 (es)
GB (1) GB2051048B (es)
GR (1) GR68518B (es)
HU (1) HU179443B (es)
IL (1) IL59967A (es)
IT (1) IT1133085B (es)
LU (1) LU82437A1 (es)
NL (1) NL8002678A (es)
NO (1) NO152607C (es)
PL (1) PL124035B1 (es)
PT (1) PT71213A (es)
SE (1) SE441747B (es)
SU (1) SU1151210A3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178453B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydrazino-4-oxo-6,7,8,9-tetrahydro-4h-p-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5158952A (en) * 1988-11-07 1992-10-27 Janssen Pharmaceutica N.V. 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity

Also Published As

Publication number Publication date
SU1151210A3 (ru) 1985-04-15
GR68518B (es) 1982-01-11
FI68825C (fi) 1985-11-11
SE8003479L (sv) 1980-11-12
GB2051048A (en) 1981-01-14
LU82437A1 (fr) 1980-07-31
DE3017564A1 (de) 1980-11-13
FI801512A (fi) 1980-11-12
AT377261B (de) 1985-02-25
HU179443B (en) 1982-10-28
PT71213A (en) 1980-06-01
IT8067719A0 (it) 1980-05-09
NL8002678A (nl) 1980-11-13
NO152607C (no) 1985-10-23
FR2456101A1 (fr) 1980-12-05
BE883217A (fr) 1980-09-01
DD150605A5 (de) 1981-09-09
PL124035B1 (en) 1982-12-31
IL59967A (en) 1984-05-31
IL59967A0 (en) 1980-07-31
FI68825B (fi) 1985-07-31
FR2456101B1 (es) 1985-04-05
CH646971A5 (de) 1984-12-28
CA1141379A (en) 1983-02-15
CS325880A2 (en) 1985-06-13
ATA247580A (de) 1984-07-15
DK204680A (da) 1980-11-12
SE441747B (sv) 1985-11-04
PL224163A1 (es) 1981-02-13
CS241025B2 (en) 1986-03-13
NO801378L (no) 1980-11-12
IT1133085B (it) 1986-07-09
JPS5615286A (en) 1981-02-14
ES491896A0 (es) 1981-02-16
GB2051048B (en) 1983-01-19
NO152607B (no) 1985-07-15

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