ES8102547A1 - Improved procedure for the preparation of feniletanolamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Improved procedure for the preparation of feniletanolamines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8102547A1
ES8102547A1 ES487548A ES487548A ES8102547A1 ES 8102547 A1 ES8102547 A1 ES 8102547A1 ES 487548 A ES487548 A ES 487548A ES 487548 A ES487548 A ES 487548A ES 8102547 A1 ES8102547 A1 ES 8102547A1
Authority
ES
Spain
Prior art keywords
feniletanolamines
translation
machine
legally binding
*** translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487548A
Other languages
Spanish (es)
Other versions
ES487548A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI790067A external-priority patent/FI59396C/en
Priority claimed from DE19792942723 external-priority patent/DE2942723A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8102547A1 publication Critical patent/ES8102547A1/en
Publication of ES487548A0 publication Critical patent/ES487548A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Procedure for obtaining feniletanolamines. Is to react 4-amino-benzaldehido with an isonitril, reducing alpha-aciloxi-acetamida obtained with a metallic hydride. Optionally, the pheniletanolamide obtained in the corresponding salt is transformed. The reaction is effected in a solvent such as tetrahydrofuran, and at temperatures that rock between 0 and 100gc, or at low temperatures: -20 to 75gc. Like hydride, boran/tetrahydrofuran is used. The reaction is effected through an aqueous base, for example, through water/ammonia. Broncolitic activity. (Machine-translation by Google Translate, not legally binding)
ES487548A 1979-01-10 1980-01-09 IMPROVED PROCEDURE FOR THE PREPARATION OF PHENYLETHANOLINES. Granted ES487548A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI790067A FI59396C (en) 1979-01-10 1979-01-10 PROCEDURE FOR THE FRAMSTATION OF AV 2- (4-AMINO-3,5-DICHLOROPHENYL) -2-CARBOXY-N-TERT-BUTYL ACETAMIDER
DE19792942723 DE2942723A1 (en) 1979-10-23 1979-10-23 Prepn. of broncholytic phenyl-ethanolamine derivs. - via new 2-acyloxy-2-phenyl-acetamide derivs.

Publications (2)

Publication Number Publication Date
ES8102547A1 true ES8102547A1 (en) 1981-01-16
ES487548A0 ES487548A0 (en) 1981-01-16

Family

ID=25781629

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487548A Granted ES487548A0 (en) 1979-01-10 1980-01-09 IMPROVED PROCEDURE FOR THE PREPARATION OF PHENYLETHANOLINES.

Country Status (18)

Country Link
AT (1) AT367398B (en)
BG (1) BG33584A3 (en)
CA (1) CA1146958A (en)
CH (1) CH645611A5 (en)
CS (1) CS214689B2 (en)
DD (2) DD150198A5 (en)
DK (2) DK159263C (en)
ES (1) ES487548A0 (en)
GR (1) GR74391B (en)
HU (2) HU188207B (en)
NL (1) NL8000126A (en)
NO (2) NO148522C (en)
PL (2) PL126876B1 (en)
PT (1) PT70661A (en)
RO (1) RO78779A (en)
SE (2) SE447102B (en)
SU (1) SU884563A3 (en)
YU (1) YU4880A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR102020008433A2 (en) 2020-04-28 2021-11-03 Universidade Federal Do Parana ARTHROPOD REPELLENTS OBTAINED FROM THE CHEMICAL TRANSFORMATION OF LACTIC ACID, LACTATES OR OTHER LACTIC ACID DERIVATIVES

Also Published As

Publication number Publication date
BG33584A3 (en) 1983-03-15
DD156179A5 (en) 1982-08-04
SE452979B (en) 1988-01-04
DK159263C (en) 1991-02-18
DK159262B (en) 1990-09-24
GR74391B (en) 1984-06-28
NO148997B (en) 1983-10-17
DD150198A5 (en) 1981-08-19
AT367398B (en) 1982-06-25
NO823159L (en) 1980-07-11
NO148522C (en) 1983-10-26
DK517289A (en) 1989-10-18
CS214689B2 (en) 1982-05-28
NO148522B (en) 1983-07-18
HU188207B (en) 1986-03-28
SE8405631L (en) 1984-11-09
YU4880A (en) 1983-06-30
DK8480A (en) 1980-07-11
ATA3380A (en) 1981-11-15
PL126876B1 (en) 1983-09-30
RO78779A (en) 1982-04-12
SE447102B (en) 1986-10-27
SE8000175L (en) 1980-07-11
CH645611A5 (en) 1984-10-15
DK517289D0 (en) 1989-10-18
SU884563A3 (en) 1981-11-23
NL8000126A (en) 1980-07-14
DK159263B (en) 1990-09-24
PT70661A (en) 1980-02-01
CA1146958A (en) 1983-05-24
DK159262C (en) 1991-02-18
ES487548A0 (en) 1981-01-16
NO794314L (en) 1980-07-11
PL126046B1 (en) 1983-07-30
PL221288A1 (en) 1980-12-15
NO148997C (en) 1984-01-25
HU181681B (en) 1983-11-28
SE8405631D0 (en) 1984-11-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303