ES438313A1 - Un procedimiento para la preparacion de 3-tiometilergolinas. - Google Patents

Un procedimiento para la preparacion de 3-tiometilergolinas.

Info

Publication number: ES438313A1
Authority: ES; Spain
Prior art keywords: formula; see formula; alq; see; phenyl
Prior art date: 1974-06-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES438313A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-06

Publication date

1977-05-16

1975-06-06 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1977-05-16 Publication of ES438313A1 publication Critical patent/ES438313A1/es

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES438313A 1974-06-06 1975-06-06 Un procedimiento para la preparacion de 3-tiometilergolinas. Expired ES438313A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines

Publications (1)

Publication Number	Publication Date
ES438313A1 true ES438313A1 (es)	1977-05-16

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES438313A Expired ES438313A1 (es)	1974-06-06	1975-06-06	Un procedimiento para la preparacion de 3-tiometilergolinas.

Country Status (27)

Country	Link
US (1)	US3901894A (da)
JP (1)	JPS582946B2 (da)
AR (1)	AR210736A1 (da)
AT (1)	AT344333B (da)
AU (1)	AU507574B2 (da)
BE (1)	BE829887A (da)
BG (1)	BG24812A3 (da)
CA (1)	CA1071623A (da)
CH (1)	CH617196A5 (da)
CS (1)	CS199591B2 (da)
DD (1)	DD120438A5 (da)
DE (1)	DE2524575A1 (da)
DK (1)	DK144160C (da)
ES (1)	ES438313A1 (da)
FR (1)	FR2273542A1 (da)
GB (1)	GB1505296A (da)
HU (1)	HU173590B (da)
IE (1)	IE41474B1 (da)
IL (1)	IL47424A (da)
NL (1)	NL180911C (da)
PH (1)	PH10992A (da)
PL (1)	PL95738B1 (da)
RO (1)	RO77543A (da)
SE (1)	SE420095B (da)
SU (1)	SU613724A3 (da)
YU (1)	YU145575A (da)
ZA (1)	ZA753638B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) *	1977-07-05	1988-03-31	Simes	Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) *	1982-05-12	1983-11-18	Roussel Uclaf	Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) *	1982-08-09	1985-06-28	Sandoz Ag	Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) *	1985-11-13	1988-09-02	Roussel Uclaf	Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
ATE424414T1 (de)	2001-06-08	2009-03-15	Sod Conseils Rech Applic	Chimere somatostatin-dopamin-analoga
US7019140B2 (en) *	2002-03-15	2006-03-28	Antibioticos S.P.A.	Process for the synthesis of pergolide
RU2015120570A (ru)	2012-11-01	2016-12-20	Ипсен Фарма С.А.С.	Аналоги соматостатина и их димеры
TWI523863B (zh)	2012-11-01	2016-03-01	艾普森藥品公司	體抑素－多巴胺嵌合體類似物
WO2019234069A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH507248A (de) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
DE1935556A1 (de) *	1969-07-12	1971-01-21	Hoechst Ag	Verfahren zur Herstellung von Lysergol
JPS5012398A (da) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/ja not_active Expired
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 CS CS753882A patent/CS199591B2/cs unknown
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/xx not_active IP Right Cessation
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/de not_active Ceased
- 1975-06-03 SE SE7506327A patent/SE420095B/xx not_active IP Right Cessation
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 HU HU75EI623A patent/HU173590B/hu unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 DK DK249975A patent/DK144160C/da not_active IP Right Cessation
- 1975-06-04 BG BG7500030188A patent/BG24812A3/xx unknown
- 1975-06-04 PL PL1975180897A patent/PL95738B1/pl unknown
- 1975-06-04 IL IL47424A patent/IL47424A/xx unknown
- 1975-06-05 FR FR7517652A patent/FR2273542A1/fr active Granted
- 1975-06-05 ZA ZA3638A patent/ZA753638B/xx unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/ru active
- 1975-06-05 YU YU01455/75A patent/YU145575A/xx unknown
- 1975-06-05 RO RO7582445A patent/RO77543A/ro unknown
- 1975-06-05 AT AT427975A patent/AT344333B/de not_active IP Right Cessation
- 1975-06-05 BE BE1006709A patent/BE829887A/xx not_active IP Right Cessation
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 ES ES438313A patent/ES438313A1/es not_active Expired
- 1975-06-06 AR AR259118A patent/AR210736A1/es active
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
YU145575A (en)	1982-02-28
DD120438A5 (da)	1976-06-12
NL180911B (nl)	1986-12-16
AR210736A1 (es)	1977-09-15
IE41474L (en)	1975-12-06
US3901894A (en)	1975-08-26
CS199591B2 (en)	1980-07-31
DK249975A (da)	1975-12-07
IL47424A (en)	1979-11-30
BG24812A3 (en)	1978-05-12
SU613724A3 (ru)	1978-06-30
HU173590B (hu)	1979-06-28
PL95738B1 (pl)	1977-11-30
FR2273542B1 (da)	1978-10-06
JPS582946B2 (ja)	1983-01-19
SE7506327L (sv)	1975-12-08
DE2524575A1 (de)	1975-12-18
ATA427975A (de)	1977-11-15
BE829887A (fr)	1975-12-05
NL180911C (nl)	1987-05-18
AT344333B (de)	1978-07-10
IL47424A0 (en)	1975-08-31
RO77543A (ro)	1982-02-26
FR2273542A1 (fr)	1976-01-02
GB1505296A (en)	1978-03-30
IE41474B1 (en)	1980-01-16
CA1071623A (en)	1980-02-12
AU507574B2 (en)	1980-02-21
NL7506584A (nl)	1975-12-09
PH10992A (en)	1977-10-20
JPS50160300A (da)	1975-12-25
DK144160C (da)	1982-06-07
SE420095B (sv)	1981-09-14
ZA753638B (en)	1977-01-26
AU8182775A (en)	1976-12-09
CH617196A5 (da)	1980-05-14
DK144160B (da)	1981-12-28

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Legal Events

Date	Code	Title	Description
1998-03-16	FD1A	Patent lapsed	Effective date: 19980202