DK249975A - Fremgangsmade til fremstilling af 8-thiomethylergolin-forbindelser - Google Patents

Fremgangsmade til fremstilling af 8-thiomethylergolin-forbindelser

Info

Publication number: DK249975A
Authority: DK; Denmark
Prior art keywords: thiomethylergoline; compounds; preparation; thiomethylergoline compounds
Prior art date: 1974-06-06

Application number

DK249975A

Other languages

English (en)

Other versions

DK144160C (da

DK144160B (da

Inventor

E C Kornfeld

N J Bach

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-06

Filing date

1975-06-04

Publication date

1975-12-07

1975-06-04 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1975-12-07 Publication of DK249975A publication Critical patent/DK249975A/da

1981-12-28 Publication of DK144160B publication Critical patent/DK144160B/da

1982-06-07 Application granted granted Critical

1982-06-07 Publication of DK144160C publication Critical patent/DK144160C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK249975A 1974-06-06 1975-06-04 Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner DK144160C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US477136A US3901894A (en)	1974-06-06	1974-06-06	8-thiomethylergolines
US47713674		1974-06-06

Publications (3)

Publication Number	Publication Date
DK249975A true DK249975A (da)	1975-12-07
DK144160B DK144160B (da)	1981-12-28
DK144160C DK144160C (da)	1982-06-07

Family

ID=23894677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK249975A DK144160C (da)	1974-06-06	1975-06-04	Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner

Country Status (27)

Country	Link
US (1)	US3901894A (da)
JP (1)	JPS582946B2 (da)
AR (1)	AR210736A1 (da)
AT (1)	AT344333B (da)
AU (1)	AU507574B2 (da)
BE (1)	BE829887A (da)
BG (1)	BG24812A3 (da)
CA (1)	CA1071623A (da)
CH (1)	CH617196A5 (da)
CS (1)	CS199591B2 (da)
DD (1)	DD120438A5 (da)
DE (1)	DE2524575A1 (da)
DK (1)	DK144160C (da)
ES (1)	ES438313A1 (da)
FR (1)	FR2273542A1 (da)
GB (1)	GB1505296A (da)
HU (1)	HU173590B (da)
IE (1)	IE41474B1 (da)
IL (1)	IL47424A (da)
NL (1)	NL180911C (da)
PH (1)	PH10992A (da)
PL (1)	PL95738B1 (da)
RO (1)	RO77543A (da)
SE (1)	SE420095B (da)
SU (1)	SU613724A3 (da)
YU (1)	YU145575A (da)
ZA (1)	ZA753638B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) *	1974-12-13	1976-05-25	Eli Lilly And Company	8-Oxymethylergolines and process therefor
JPS5283894A (en) *	1976-01-01	1977-07-13	Lilly Co Eli	88thiomethyl ergoline
GB1549829A (en) *	1976-05-26	1979-08-08	Farmaceutici Italia	10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) *	1977-07-05	1988-03-31	Simes	Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) *	1978-02-08	1979-08-28	Eli Lilly And Company	6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) *	1978-02-08	1979-12-25	Eli Lilly And Company	6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) *	1979-01-11	1980-05-13	Eli Lilly And Company	6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) *	1979-10-01	1981-01-20	Eli Lilly And Company	6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) *	1982-05-03	1983-11-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) *	1982-05-12	1983-11-18	Roussel Uclaf	Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) *	1982-08-09	1985-06-28	Sandoz Ag	Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) *	1984-10-31	1984-12-05	Lilly Industries Ltd	Ergoline derivatives
US4675322A (en) *	1984-12-10	1987-06-23	Eli Lilly And Company	1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) *	1985-06-24	1989-01-31	Eli Lilly And Company	2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) *	1985-11-13	1988-09-02	Roussel Uclaf	Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) *	1986-06-27	1988-11-28	Richter Gedeon Vegyeszet	Process for preparing 2-halogenated ergoline derivatives
CA2449634C (en) *	2001-06-08	2011-08-02	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Somatostatin-dopamine chimeric analogs
EP1485382B1 (en) *	2002-03-15	2008-11-19	Antibioticos S.p.A.	Process for the synthesis of pergolide
JP2016503402A (ja)	2012-11-01	2016-02-04	イプセンファルマソシエテパールアクシオンサンプリフィエＩｐｓｅｎＰｈａｒｍａＳ．Ａ．Ｓ．	ソマトスタチン類似体及びそのダイマー
TWI523863B (zh)	2012-11-01	2016-03-01	艾普森藥品公司	體抑素－多巴胺嵌合體類似物
WO2019234069A1 (en)	2018-06-08	2019-12-12	Boehringer Ingelheim Vetmedica Gmbh	Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE712054A (da) *	1967-03-16	1968-07-15
DE1935556A1 (de) *	1969-07-12	1971-01-21	Hoechst Ag	Verfahren zur Herstellung von Lysergol
JPS5012398A (da) *	1973-06-08	1975-02-07

1974
- 1974-06-06 US US477136A patent/US3901894A/en not_active Expired - Lifetime
1975
- 1975-05-16 JP JP50059191A patent/JPS582946B2/ja not_active Expired
- 1975-06-03 CA CA228,332A patent/CA1071623A/en not_active Expired
- 1975-06-03 CS CS753882A patent/CS199591B2/cs unknown
- 1975-06-03 GB GB23869/75A patent/GB1505296A/en not_active Expired
- 1975-06-03 IE IE1221/75A patent/IE41474B1/en unknown
- 1975-06-03 NL NLAANVRAGE7506584,A patent/NL180911C/xx not_active IP Right Cessation
- 1975-06-03 HU HU75EI623A patent/HU173590B/hu unknown
- 1975-06-03 DE DE19752524575 patent/DE2524575A1/de not_active Ceased
- 1975-06-03 PH PH17225A patent/PH10992A/en unknown
- 1975-06-03 SE SE7506327A patent/SE420095B/xx not_active IP Right Cessation
- 1975-06-04 PL PL1975180897A patent/PL95738B1/pl unknown
- 1975-06-04 DK DK249975A patent/DK144160C/da not_active IP Right Cessation
- 1975-06-04 BG BG7500030188A patent/BG24812A3/xx unknown
- 1975-06-04 AU AU81827/75A patent/AU507574B2/en not_active Expired
- 1975-06-04 IL IL47424A patent/IL47424A/xx unknown
- 1975-06-05 FR FR7517652A patent/FR2273542A1/fr active Granted
- 1975-06-05 BE BE1006709A patent/BE829887A/xx not_active IP Right Cessation
- 1975-06-05 YU YU01455/75A patent/YU145575A/xx unknown
- 1975-06-05 AT AT427975A patent/AT344333B/de not_active IP Right Cessation
- 1975-06-05 RO RO7582445A patent/RO77543A/ro unknown
- 1975-06-05 SU SU752140862A patent/SU613724A3/ru active
- 1975-06-05 ZA ZA3638A patent/ZA753638B/xx unknown
- 1975-06-06 CH CH731075A patent/CH617196A5/de not_active IP Right Cessation
- 1975-06-06 AR AR259118A patent/AR210736A1/es active
- 1975-06-06 ES ES438313A patent/ES438313A1/es not_active Expired
1976
- 1976-06-05 DD DD186472A patent/DD120438A5/xx unknown

Also Published As

Publication number	Publication date
BE829887A (fr)	1975-12-05
SE7506327L (sv)	1975-12-08
DK144160C (da)	1982-06-07
SU613724A3 (ru)	1978-06-30
FR2273542A1 (fr)	1976-01-02
PH10992A (en)	1977-10-20
JPS50160300A (da)	1975-12-25
JPS582946B2 (ja)	1983-01-19
GB1505296A (en)	1978-03-30
PL95738B1 (pl)	1977-11-30
AU507574B2 (en)	1980-02-21
DE2524575A1 (de)	1975-12-18
IL47424A (en)	1979-11-30
IE41474L (en)	1975-12-06
AU8182775A (en)	1976-12-09
NL7506584A (nl)	1975-12-09
ES438313A1 (es)	1977-05-16
RO77543A (ro)	1982-02-26
NL180911B (nl)	1986-12-16
FR2273542B1 (da)	1978-10-06
BG24812A3 (en)	1978-05-12
CS199591B2 (en)	1980-07-31
IL47424A0 (en)	1975-08-31
AR210736A1 (es)	1977-09-15
CH617196A5 (da)	1980-05-14
DD120438A5 (da)	1976-06-12
SE420095B (sv)	1981-09-14
CA1071623A (en)	1980-02-12
AT344333B (de)	1978-07-10
US3901894A (en)	1975-08-26
ZA753638B (en)	1977-01-26
ATA427975A (de)	1977-11-15
NL180911C (nl)	1987-05-18
DK144160B (da)	1981-12-28
IE41474B1 (en)	1980-01-16
HU173590B (hu)	1979-06-28
YU145575A (en)	1982-02-28

Legal Events

Date	Code	Title	Description
1988-08-29	PBP	Patent lapsed

Publication	Publication Date	Title
DK145341C (da)	1983-03-28	Analogifremgangsmaade til fremstilling af pyridylguanidiner
DK429175A (da)	1976-03-26	Katalysatorer til hydroomdannelse af carbonhydrider
DK249975A (da)	1975-12-07	Fremgangsmade til fremstilling af 8-thiomethylergolin-forbindelser
DK173675A (da)	1975-10-24	Fremgangsmade til fremstilling af mangandioxid
DK251875A (da)	1975-12-06	Fremgangsmade til kontinuerlig forestering af chlorsilaner
DK464175A (da)	1976-04-17	Fremgangsmade til kontinuerlig fremstilling af lineere polyestere
DK144298C (da)	1982-07-12	Fremgangsmaade til fremstilling af alkyl-tert-butylethere
DK254975A (da)	1975-12-13	Fremgangsmade til fremstilling af aminotetralolforbindelser
DK385475A (da)	1976-03-14	Fremgangsmade til fremstilling af secoprostaglandiner
DK152765C (da)	1988-10-10	Fremgangsmaade til fremstilling af d-(-)-n-carbamylphenylglycin
DK292375A (da)	1975-12-29	Fremgangsmade til fremstilling af gipsprodukter
DK225075A (da)	1975-11-29	Fremgangsmade til fremstilling af alfa-6--desoxy5-hydroxytetracyclin
DK141849C (da)	1980-11-10	Fremgangsmaade til fremstilling af slagseje vinylaromat-podecopolymere
DK206375A (da)	1975-11-12	Fremgangsmade til fremstilling af thiaprostaglandiner
DK574075A (da)	1976-06-19	Fremgangsmade til fremstilling af 2-methoxybenzamider
DK153389C (da)	1988-11-21	Fremgangsmaade til fremstilling af pinacolon
DK146718C (da)	1984-05-21	Analogifremgangsmaade til fremstilling af benzobicyklononener
DK543875A (da)	1976-06-04	Fremgangsmade til fremstilling af hydroxyphenylacetonitriler
DK528475A (da)	1976-05-26	Fremgangsmade til fremstilling af tetramethylethylendiamin
DK583775A (da)	1976-06-21	Fremgangsmade til fremstilling af 3-fluorbenzodiazepiner
DK402875A (da)	1976-03-11	Fremgangsmade til fremstilling af meta-substituerede halogenphenoler
DK405775A (da)	1976-03-13	Fremgangsmade til fremstilling af alkanolaminer
DK585875A (da)	1976-06-25	Fremgangsmade til fremstilling af substituerede 3-methylencephamsulfoxider
DK162280C (da)	1992-03-16	Fremgangsmaade til fremstilling af 3-formylpinan
DK137539C (da)	1978-09-04	Fremgangsmaade til fremstilling af 11beta-fluor-4-androsten-3-oner