ES372334A1 - Procedure for the obtaining of aminocetonas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of aminocetonas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES372334A1 ES372334A1 ES372334A ES372334A ES372334A1 ES 372334 A1 ES372334 A1 ES 372334A1 ES 372334 A ES372334 A ES 372334A ES 372334 A ES372334 A ES 372334A ES 372334 A1 ES372334 A1 ES 372334A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl moiety
- formula
- see formula
- salts
- chosen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- 125000005219 aminonitrile group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- 150000002989 phenols Chemical class 0.000 abstract 2
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- -1 aliphatic alcohols Chemical class 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for obtaining amino ketones, of general formula: **(See formula)** in which R1 is chosen from the remains: **(See formula)** wherein R4 is chosen from a lower alkyl moiety and a benzyl moiety and R5 is selected from a hydrogen atom, a lower alkyl moiety and a benzyl moiety; R2 is chosen from a hydrogen atom and a methyl residue; R3 is chosen from hydrogen and a lower alkyl moiety and X means an alkyl moiety with a maximum of 6 carbon atoms, respectively, in the case that the R2 and R3 moieties mean hydrogen, they are defined as the grouping: **(See formula)** in which n means an integer from 2 - 12 and R1 has the above meaning, respectively, of its salts, by condensation of aminonitriles with phenols, respectively their ethers, in the presence of aluminum chloride and halogenated hydracids, in a usual solvent for the Friedel-Crafts reactions, characterized in that the aminonitriles of general formula: **(See formula)** Where R2 and R3 have the definition above and X'means an alkyl moiety with a maximum of 6 carbon atoms, respectively, in the case that the R2 and R3 moieties signify hydrogen, the group - (CH2) n-NH -CH2-CN, in which n has the definition above, respectively its salts, are reacted with phenols, respectively their ethers, of general formula: R1H (III) wherein R1 has the definition above, at temperatures below 40ºC, preferably at most 30ºC, the imino compounds of general formula being released into the reaction mixture, by addition of lower aliphatic alcohols: **(See formula)** Where R1, R2 and R3 have the definition above and X'' means an alkyl moiety with a maximum of 6 carbon atoms, respectively, in the event that R2 and R3 signify hydrogen, the group: **(See formula)** respectively their salts, and these, if appropriate after isolation with water or aqueous alcohols, are hydrolyzed to the amino ketones of formula I and, if appropriate, the salts are subsequently released. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT987268A AT286269B (en) | 1968-10-10 | 1968-10-10 | Process for the production of Aminoaketonen and their salts |
Publications (1)
Publication Number | Publication Date |
---|---|
ES372334A1 true ES372334A1 (en) | 1971-10-16 |
Family
ID=3618062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES372334A Expired ES372334A1 (en) | 1968-10-10 | 1969-10-09 | Procedure for the obtaining of aminocetonas. (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
Country | Link |
---|---|
AT (1) | AT286269B (en) |
CH (1) | CH525185A (en) |
DK (1) | DK123167B (en) |
ES (1) | ES372334A1 (en) |
FI (1) | FI54470C (en) |
NL (1) | NL164846C (en) |
SE (1) | SE366295B (en) |
YU (1) | YU34115B (en) |
-
1968
- 1968-10-10 AT AT987268A patent/AT286269B/en not_active IP Right Cessation
-
1969
- 1969-09-15 CH CH1390769A patent/CH525185A/en not_active IP Right Cessation
- 1969-10-02 FI FI2841/69A patent/FI54470C/en active
- 1969-10-06 NL NL6915086.A patent/NL164846C/en not_active IP Right Cessation
- 1969-10-07 SE SE13755/69A patent/SE366295B/xx unknown
- 1969-10-09 DK DK539169AA patent/DK123167B/en unknown
- 1969-10-09 ES ES372334A patent/ES372334A1/en not_active Expired
- 1969-10-10 YU YU2552/69A patent/YU34115B/en unknown
Also Published As
Publication number | Publication date |
---|---|
NL164846C (en) | 1981-02-16 |
SE366295B (en) | 1974-04-22 |
NL164846B (en) | 1980-09-15 |
NL6915086A (en) | 1970-04-14 |
FI54470C (en) | 1978-12-11 |
YU34115B (en) | 1978-12-31 |
FI54470B (en) | 1978-08-31 |
DK123167B (en) | 1972-05-23 |
YU255269A (en) | 1978-06-30 |
CH525185A (en) | 1972-07-15 |
AT286269B (en) | 1970-12-10 |
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