ES371235A1 - Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES371235A1
ES371235A1 ES371235A ES371235A ES371235A1 ES 371235 A1 ES371235 A1 ES 371235A1 ES 371235 A ES371235 A ES 371235A ES 371235 A ES371235 A ES 371235A ES 371235 A1 ES371235 A1 ES 371235A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl group
group
translation
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES371235A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES371235A1 publication Critical patent/ES371235A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedure for the preparation of new benzofuran derivatives, of the general formula I, **(See formula)** in which R1 means hydrogen, a halogen atom up to the atomic number 35, an alkyl group or an alkoxy group with, each time, 2 carbon atoms at most or the nitro group, R2 stands for hydrogen, a halogen atom up to atomic number 35, an alkyl group or an alkoxy group with each having 2 carbon atoms at most, R3 means an alkyl group with 4 carbon atoms at most and R4 and R5 each denote an alkyl group with at most 4 carbon atoms or both together with the adjacent nitrogen atom as -NR4R5, the 1-pyrrolidinyl, piperidinic or morpholinic group, and their addition salts with inorganic and organic acids, characterized in that a compound of the general formula II, **(See formula)** in which R1, R2, R3, R4 and R5 have the significance indicated above, it is reduced by a complex hydride or by a hydrazine hydrate in the presence of alkali hydroxides and if desired the obtained benzofuran derivative falling under general formula I is transformed into an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES371235A 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES371235A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1184669A CH504429A (en) 1969-08-05 1969-08-05 3-(2-amino-ethyl)-benzofurans

Publications (1)

Publication Number Publication Date
ES371235A1 true ES371235A1 (en) 1971-08-16

Family

ID=4377461

Family Applications (3)

Application Number Title Priority Date Filing Date
ES371237A Expired ES371237A1 (en) 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)
ES371235A Expired ES371235A1 (en) 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)
ES371236A Expired ES371236A1 (en) 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES371237A Expired ES371237A1 (en) 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES371236A Expired ES371236A1 (en) 1969-08-05 1969-09-05 Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
CH (2) CH504463A (en)
ES (3) ES371237A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5087638A (en) * 1984-06-20 1992-02-11 Merck Frosst Canada, Inc. Benzofuran derivatives

Also Published As

Publication number Publication date
CH504463A (en) 1971-03-15
ES371237A1 (en) 1971-08-16
ES371236A1 (en) 1971-08-16
CH504429A (en) 1971-03-15

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