ES308478A1 - A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES308478A1
ES308478A1 ES0308478A ES308478A ES308478A1 ES 308478 A1 ES308478 A1 ES 308478A1 ES 0308478 A ES0308478 A ES 0308478A ES 308478 A ES308478 A ES 308478A ES 308478 A1 ES308478 A1 ES 308478A1
Authority
ES
Spain
Prior art keywords
formula
translation
procedure
preparation
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0308478A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US412325A external-priority patent/US3215688A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES308478A1 publication Critical patent/ES308478A1/en
Expired legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A procedure for the preparation of benzodiazepine derivatives of the general formula **(See formula)** where R1 represents amino, lower alkanoylamino, lower alkylidonamino or phenylalkylidonamino lower, R2 represents hydrogen or lower alkyl, represents phenyl, pyridyl, halophenyl, trifluoromethylphenyl, lower alkylphenyl, nitrophenyl or lower alkoxyphenyl, represents hydrogen, halogen, nitro, trifluoromethyl, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulfinyl, or lower alkylsulfonyl, and the corresponding 4-oxides and acid addition salts of such compounds, a process consisting of treating the 1-sodium derivative of a compound of the formula **(See formula)** where R2, R3 and R4 have the same meaning as explained before, or a corresponding 4-oxide, with chloramine; if desired, alkanoylate the product obtained or react it with a compound of the formula R = O III wherein R represents a lower alkylidene or lower phenylalkylidene group, and, if desired, converting a reaction basic product into an acid addition salt thereof. (Machine-translation by Google Translate, not legally binding)
ES0308478A 1964-01-24 1965-01-23 A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES308478A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33986164A 1964-01-24 1964-01-24
US412325A US3215688A (en) 1961-02-10 1964-11-19 Certain benzodiazepine compounds

Publications (1)

Publication Number Publication Date
ES308478A1 true ES308478A1 (en) 1965-06-01

Family

ID=26991847

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0308478A Expired ES308478A1 (en) 1964-01-24 1965-01-23 A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
DK (1) DK106333C (en)
ES (1) ES308478A1 (en)

Also Published As

Publication number Publication date
DK106333C (en) 1967-01-23

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