ES2170589T3 - Composicion farmaceutica para inyecciones a base de paracetamol. - Google Patents

Composicion farmaceutica para inyecciones a base de paracetamol.

Info

Publication number
ES2170589T3
ES2170589T3 ES99944308T ES99944308T ES2170589T3 ES 2170589 T3 ES2170589 T3 ES 2170589T3 ES 99944308 T ES99944308 T ES 99944308T ES 99944308 T ES99944308 T ES 99944308T ES 2170589 T3 ES2170589 T3 ES 2170589T3
Authority
ES
Spain
Prior art keywords
paracetamol
pharmaceutical composition
based injections
volume
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99944308T
Other languages
English (en)
Inventor
Giovanni Cavallo
Mario Pinza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Application granted granted Critical
Publication of ES2170589T3 publication Critical patent/ES2170589T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composición farmacéutica, caracterizada porque a) comprende i) paracetamol ii) de 1 a 4 partes en volumen de etanol por cada parte en peso de paracetamol, y iii) de 1 a 5 partes en volumen de polietilenglicol por cada parte en peso de paracetamol, b) es sustancialmente anhidra, y c) forma una disolución transparente para inyección con 4-10 partes en volumen de agua por cada parte en peso de paracetamol.
ES99944308T 1998-07-31 1999-07-27 Composicion farmaceutica para inyecciones a base de paracetamol. Expired - Lifetime ES2170589T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI001795A IT1301976B1 (it) 1998-07-31 1998-07-31 Composizione farmaceutica iniettabile a base di paracetamolo

Publications (1)

Publication Number Publication Date
ES2170589T3 true ES2170589T3 (es) 2002-08-01

Family

ID=11380579

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99944308T Expired - Lifetime ES2170589T3 (es) 1998-07-31 1999-07-27 Composicion farmaceutica para inyecciones a base de paracetamol.

Country Status (25)

Country Link
US (1) US6423749B1 (es)
EP (1) EP1094802B1 (es)
JP (1) JP2002522384A (es)
KR (1) KR20010071061A (es)
CN (1) CN1146413C (es)
AR (1) AR020638A1 (es)
AT (1) ATE212225T1 (es)
AU (1) AU754902B2 (es)
BG (1) BG105274A (es)
CA (1) CA2338728C (es)
DE (1) DE69900823T2 (es)
DK (1) DK1094802T3 (es)
EA (1) EA002648B1 (es)
ES (1) ES2170589T3 (es)
GE (1) GEP20032986B (es)
HK (1) HK1036011A1 (es)
HU (1) HUP0102842A3 (es)
IL (1) IL140920A0 (es)
IT (1) IT1301976B1 (es)
PL (1) PL196604B1 (es)
PT (1) PT1094802E (es)
SI (1) SI1094802T1 (es)
SK (1) SK1222001A3 (es)
TR (1) TR200100273T2 (es)
WO (1) WO2000007588A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2796843B1 (fr) * 1999-07-29 2003-05-09 So Ge Val Sa Composition antipyretique concentree et stabilisee a usage veterinaire destine a etre incorporee a l'alimentation des animaux ainsi que procede d'incorporation de cette composition a l'eau de boisson d'animaux
ITMI20012135A1 (it) 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo
FR2851164B1 (fr) * 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
US20050143654A1 (en) * 2003-11-29 2005-06-30 Karel Zuiderveld Systems and methods for segmented volume rendering using a programmable graphics pipeline
FR2862872A1 (fr) * 2003-12-02 2005-06-03 Palbian Snc Composition a l'etat aqueux pour l'application perfusable d'un principe actif, notamment pharmacologique tel que le paracetamol.
CA2628806C (en) * 2006-07-18 2012-08-21 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
ES2321906B1 (es) * 2008-11-28 2010-02-09 Laboratorios Normon, S.A. Composicion farmaceutica que comprende una solucion acuosa de paracetamol.
EP2243477A1 (de) * 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
EP2308463A1 (en) * 2009-10-12 2011-04-13 EMP Pharma GmbH Aqueous acetaminophen compositions and method of preparation
CN101816643B (zh) * 2009-12-31 2013-02-13 王石齐 含有双氯芬酸钠和对乙酰氨基酚的药物组合物
EP2377516B1 (en) 2010-04-14 2012-06-20 B. Braun Melsungen AG Acetaminophen composition
ES2866636T3 (es) * 2010-06-30 2021-10-19 Troikaa Pharmaceuticals Ltd Composiciones farmacéuticas que comprenden paracetamol y proceso para preparar las mismas
CN102258485A (zh) * 2011-01-11 2011-11-30 北京润德康医药技术有限公司 一种含对乙酰氨基酚的注射用制剂及其应用
US20150141518A1 (en) * 2013-11-21 2015-05-21 Emphascience, Inc. Water-miscible stable solution composition for pharmaceutically active ingredients that are poorly soluble in water and susceptible to chemical degradation
US20160144033A1 (en) * 2014-11-21 2016-05-26 Emphascience, Inc. Concentrated acetaminophen solution
KR20170099911A (ko) * 2014-12-20 2017-09-01 트로이카 파마슈티칼스 리미티드 파라세타몰 주사 제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307073A (en) * 1980-08-08 1981-12-22 The Research Foundation Of State University Of New York Method and composition for reducing the toxicity of acetaminophen
DD279405A1 (de) 1989-01-10 1990-06-06 Berlin Chemie Veb Verfahren zur herstellung eines parenteral applizierbaren analgetikums/antipyretikums
KR930011994B1 (ko) 1991-08-16 1993-12-23 대광제약 주식회사 파라세타몰의 생체이용율을 높이는 방법 및 이 생체이용율이 높아진 파라세타몰을 함유한 제제
FR2751875B1 (fr) 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation

Also Published As

Publication number Publication date
HK1036011A1 (en) 2001-12-21
CA2338728A1 (en) 2000-02-17
JP2002522384A (ja) 2002-07-23
DE69900823D1 (de) 2002-03-14
DE69900823T2 (de) 2002-08-29
AU5729499A (en) 2000-02-28
EA200100187A1 (ru) 2001-08-27
HUP0102842A3 (en) 2003-12-29
ITMI981795A0 (it) 1998-07-31
EA002648B1 (ru) 2002-08-29
CN1146413C (zh) 2004-04-21
HUP0102842A2 (hu) 2002-05-29
US6423749B1 (en) 2002-07-23
ATE212225T1 (de) 2002-02-15
DK1094802T3 (da) 2002-05-06
AR020638A1 (es) 2002-05-22
PL196604B1 (pl) 2008-01-31
KR20010071061A (ko) 2001-07-28
IT1301976B1 (it) 2000-07-20
TR200100273T2 (tr) 2001-05-21
PL345767A1 (en) 2002-01-02
SI1094802T1 (en) 2002-08-31
ITMI981795A1 (it) 2000-01-31
GEP20032986B (en) 2003-06-25
AU754902B2 (en) 2002-11-28
EP1094802B1 (en) 2002-01-23
WO2000007588A1 (en) 2000-02-17
PT1094802E (pt) 2002-07-31
SK1222001A3 (en) 2001-09-11
IL140920A0 (en) 2002-02-10
EP1094802A1 (en) 2001-05-02
CA2338728C (en) 2008-01-22
CN1311672A (zh) 2001-09-05
BG105274A (en) 2001-11-30

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