ES2168971A1 - Procedimiento de produccion de beta-caroteno. - Google Patents
Procedimiento de produccion de beta-caroteno.Info
- Publication number
- ES2168971A1 ES2168971A1 ES200001792A ES200001792A ES2168971A1 ES 2168971 A1 ES2168971 A1 ES 2168971A1 ES 200001792 A ES200001792 A ES 200001792A ES 200001792 A ES200001792 A ES 200001792A ES 2168971 A1 ES2168971 A1 ES 2168971A1
- Authority
- ES
- Spain
- Prior art keywords
- carotene
- beta
- production
- blakeslea
- phycomyces
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
- A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/931—Mucor
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Procedimiento de producción de {be}-caroteno. La presente invención se refiere a un nuevo procedimiento para la producción de {be}-caroteno a partir de cultivos sumergidos de hongos mucorales como Blakeslea, Choanephora o Phycomyces mediante la adición al medio de cultivo de lecitina conjuntamente con un control de pH una vez comenzada la fermentación, procedimiento que incluye un paso de recuperación de {be}-caroteno que permite obtener una simplificación en el proceso, una optimización en el rendimiento, junto con un incremento en la purificación del producto.
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200001792A ES2168971B1 (es) | 2000-07-19 | 2000-07-19 | Procedimiento de produccion de beta-caroteno. |
DE60105435T DE60105435T2 (de) | 2000-07-19 | 2001-07-18 | Verfahren zur herstellung von beta-karotin |
AU2001272562A AU2001272562A1 (en) | 2000-07-19 | 2001-07-18 | Method for the production of beta-carotene |
SI200130198T SI1306444T1 (en) | 2000-07-19 | 2001-07-18 | Method for the production of beta-carotene |
AT01951706T ATE275635T1 (de) | 2000-07-19 | 2001-07-18 | Verfahren zur herstellung von beta-karotin |
ES01951706T ES2223894T3 (es) | 2000-07-19 | 2001-07-18 | Metodo para la produccion de beta-caroteno. |
JP2002516345A JP4287142B2 (ja) | 2000-07-19 | 2001-07-18 | β−カロテンの製造方法 |
TR2004/02687T TR200402687T4 (tr) | 2000-07-19 | 2001-07-18 | Beta-karoten üretimi için yöntem |
PT01951706T PT1306444E (pt) | 2000-07-19 | 2001-07-18 | Metodo para producao de beta-caroteno |
PCT/ES2001/000284 WO2002010429A1 (es) | 2000-07-19 | 2001-07-18 | PROCEDIMIENTO DE PRODUCCION DE β-CAROTENO |
EP01951706A EP1306444B1 (en) | 2000-07-19 | 2001-07-18 | Method for the production of beta-carotene |
US10/333,331 US8859228B2 (en) | 2000-07-19 | 2001-07-18 | Method for the production of beta-carotene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200001792A ES2168971B1 (es) | 2000-07-19 | 2000-07-19 | Procedimiento de produccion de beta-caroteno. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2168971A1 true ES2168971A1 (es) | 2002-06-16 |
ES2168971B1 ES2168971B1 (es) | 2003-11-01 |
Family
ID=8494321
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200001792A Expired - Fee Related ES2168971B1 (es) | 2000-07-19 | 2000-07-19 | Procedimiento de produccion de beta-caroteno. |
ES01951706T Expired - Lifetime ES2223894T3 (es) | 2000-07-19 | 2001-07-18 | Metodo para la produccion de beta-caroteno. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES01951706T Expired - Lifetime ES2223894T3 (es) | 2000-07-19 | 2001-07-18 | Metodo para la produccion de beta-caroteno. |
Country Status (10)
Country | Link |
---|---|
US (1) | US8859228B2 (es) |
EP (1) | EP1306444B1 (es) |
JP (1) | JP4287142B2 (es) |
AT (1) | ATE275635T1 (es) |
AU (1) | AU2001272562A1 (es) |
DE (1) | DE60105435T2 (es) |
ES (2) | ES2168971B1 (es) |
PT (1) | PT1306444E (es) |
TR (1) | TR200402687T4 (es) |
WO (1) | WO2002010429A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2195766B1 (es) * | 2002-01-29 | 2005-04-01 | Antibioticos, S.A.U. | Procedimiento de produccion de beta-caroteno por fermentacion en cultivo mixto utilizando cepas (+) 4 (-) de blakeslea trispora. |
CN101218352B (zh) | 2005-03-18 | 2013-09-04 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
CA2658483A1 (en) | 2006-07-21 | 2008-01-24 | Xyleco, Inc. | Conversion systems for biomass |
WO2008042338A2 (en) | 2006-09-28 | 2008-04-10 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
CN101680015A (zh) | 2007-03-08 | 2010-03-24 | 比奥特伦德生物技术创新工程股份公司 | 通过发酵组成性过产类胡萝卜素的选定菌株或突变体生产高纯度类胡萝卜素的方法 |
CN102471790B (zh) * | 2009-07-29 | 2014-10-29 | 味之素株式会社 | 产生l-氨基酸的方法 |
EP2571996B1 (en) | 2010-05-17 | 2017-03-08 | Dynadis Biotehc (India) Private Limited | Process for production of high purity beta-carotene and lycopene crystals from fungal biomass |
CN102787158B (zh) | 2011-05-20 | 2015-01-21 | 浙江医药股份有限公司新昌制药厂 | 一种发酵法生产天然β-胡萝卜素的方法和应用 |
DE102014208876B4 (de) | 2014-05-12 | 2018-10-31 | Jäckering Research GmbH | Verfahren zur Herstellung von Carotinoiden durch Submersfermentation mit Mischkulturen von (+) und (-)-Stämmen des Pilzes Blakeslea trispora |
CN104557648A (zh) * | 2014-12-23 | 2015-04-29 | 嘉必优生物工程(武汉)有限公司 | 制备β-胡萝卜素的方法 |
CN109280685B (zh) * | 2017-07-21 | 2021-11-23 | 浙江医药股份有限公司新昌制药厂 | 通过增加天然类胡萝卜素发酵过程中溶氧生产天然类胡萝卜素的方法 |
CN114127259A (zh) | 2019-08-01 | 2022-03-01 | 帝斯曼知识产权资产管理有限公司 | β-胡萝卜素发酵方法 |
WO2022090547A1 (en) | 2020-10-30 | 2022-05-05 | Dsm Ip Assets B.V. | Production of carotenoids by fermentation |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2959521A (en) * | 1959-01-12 | 1960-11-08 | Grain Processing Corp | Process for preparing beta-carotene |
US3268606A (en) * | 1963-09-27 | 1966-08-23 | Upjohn Co | Beta-carotene process |
US5422247A (en) * | 1992-03-27 | 1995-06-06 | Universal Foods Corporation | Blakeslea trispora mated culture capable of increased beta-carotene production |
WO1998003480A1 (en) * | 1996-07-19 | 1998-01-29 | Gist-Brocade B.V. | PROCESS FOR THE RECOVERY OF CRYSTALLINE β-CAROTENE FROM A NATURAL SOURCE |
US5714658A (en) * | 1995-08-25 | 1998-02-03 | Skw Trostberg Aktiengesellschaft | Process for the extraction of carotenes from natural sources |
WO1998050574A1 (en) * | 1997-05-02 | 1998-11-12 | Dsm N.V. | Isolation of carotenoid crystals from microbial biomass |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5130242A (en) * | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
DE59003205D1 (de) * | 1989-07-25 | 1993-12-02 | Hoffmann La Roche | Verfahren zur Herstellung von Carotinoidpräparaten. |
CA2082959A1 (en) * | 1990-05-15 | 1991-11-16 | Richard B. Bailey | High productivity, continuous fermentation process for carotenoid-producing microorganisms |
US5466599A (en) * | 1993-04-19 | 1995-11-14 | Universal Foods Corporation | Astaxanthin over-producing strains of phaffia rhodozyma |
DE4429506B4 (de) * | 1994-08-19 | 2007-09-13 | Degussa Gmbh | Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe |
US6048846A (en) * | 1998-02-26 | 2000-04-11 | Cochran; Timothy M. | Compositions used in human treatment |
US6309677B1 (en) * | 1998-03-24 | 2001-10-30 | Amway Corporation | Multi-carotenoid product |
US6262284B1 (en) * | 1998-10-21 | 2001-07-17 | University Of Maryland | Process for extraction and purification of lutein, zeaxanthin and rare carotenoids from marigold flowers and plants |
JP2004514419A (ja) * | 2000-07-13 | 2004-05-20 | ビタテネ、ソシエダッド アノニマ | カロチノイドを含有する水分散性配合物の製造方法 |
-
2000
- 2000-07-19 ES ES200001792A patent/ES2168971B1/es not_active Expired - Fee Related
-
2001
- 2001-07-18 EP EP01951706A patent/EP1306444B1/en not_active Expired - Lifetime
- 2001-07-18 JP JP2002516345A patent/JP4287142B2/ja not_active Expired - Lifetime
- 2001-07-18 AT AT01951706T patent/ATE275635T1/de active
- 2001-07-18 US US10/333,331 patent/US8859228B2/en not_active Expired - Fee Related
- 2001-07-18 PT PT01951706T patent/PT1306444E/pt unknown
- 2001-07-18 TR TR2004/02687T patent/TR200402687T4/xx unknown
- 2001-07-18 ES ES01951706T patent/ES2223894T3/es not_active Expired - Lifetime
- 2001-07-18 DE DE60105435T patent/DE60105435T2/de not_active Expired - Lifetime
- 2001-07-18 AU AU2001272562A patent/AU2001272562A1/en not_active Abandoned
- 2001-07-18 WO PCT/ES2001/000284 patent/WO2002010429A1/es active IP Right Grant
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2959521A (en) * | 1959-01-12 | 1960-11-08 | Grain Processing Corp | Process for preparing beta-carotene |
US3268606A (en) * | 1963-09-27 | 1966-08-23 | Upjohn Co | Beta-carotene process |
US5422247A (en) * | 1992-03-27 | 1995-06-06 | Universal Foods Corporation | Blakeslea trispora mated culture capable of increased beta-carotene production |
US5714658A (en) * | 1995-08-25 | 1998-02-03 | Skw Trostberg Aktiengesellschaft | Process for the extraction of carotenes from natural sources |
WO1998003480A1 (en) * | 1996-07-19 | 1998-01-29 | Gist-Brocade B.V. | PROCESS FOR THE RECOVERY OF CRYSTALLINE β-CAROTENE FROM A NATURAL SOURCE |
WO1998050574A1 (en) * | 1997-05-02 | 1998-11-12 | Dsm N.V. | Isolation of carotenoid crystals from microbial biomass |
Also Published As
Publication number | Publication date |
---|---|
WO2002010429A1 (es) | 2002-02-07 |
DE60105435T2 (de) | 2005-09-22 |
ES2223894T3 (es) | 2005-03-01 |
JP2004504853A (ja) | 2004-02-19 |
ES2168971B1 (es) | 2003-11-01 |
DE60105435D1 (de) | 2004-10-14 |
TR200402687T4 (tr) | 2004-11-22 |
AU2001272562A1 (en) | 2002-02-13 |
JP4287142B2 (ja) | 2009-07-01 |
EP1306444B1 (en) | 2004-09-08 |
US8859228B2 (en) | 2014-10-14 |
ATE275635T1 (de) | 2004-09-15 |
US20040067550A1 (en) | 2004-04-08 |
EP1306444A1 (en) | 2003-05-02 |
PT1306444E (pt) | 2004-11-30 |
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Legal Events
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