IT1291143B1 - Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina - Google Patents

Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina

Info

Publication number
IT1291143B1
IT1291143B1 IT97RM000222A ITRM970222A IT1291143B1 IT 1291143 B1 IT1291143 B1 IT 1291143B1 IT 97RM000222 A IT97RM000222 A IT 97RM000222A IT RM970222 A ITRM970222 A IT RM970222A IT 1291143 B1 IT1291143 B1 IT 1291143B1
Authority
IT
Italy
Prior art keywords
carnitine
pct
solid compositions
carnitine choline
alcanoyl
Prior art date
Application number
IT97RM000222A
Other languages
English (en)
Inventor
Mose Santaniello
Nazareno Scafetta
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT97RM000222A priority Critical patent/IT1291143B1/it
Priority to US09/402,650 priority patent/US6080786A/en
Priority to AU70777/98A priority patent/AU731223B2/en
Priority to SI9830051T priority patent/SI0975581T1/xx
Priority to EP98917598A priority patent/EP0975581B1/en
Priority to DK98917598T priority patent/DK0975581T3/da
Priority to AT98917598T priority patent/ATE208759T1/de
Priority to CA002286631A priority patent/CA2286631C/en
Priority to DE69802518T priority patent/DE69802518T2/de
Priority to JP54538898A priority patent/JP4046361B2/ja
Priority to PT98917598T priority patent/PT975581E/pt
Priority to PCT/IT1998/000080 priority patent/WO1998047857A1/en
Priority to NZ500535A priority patent/NZ500535A/en
Priority to BRPI9808908-0A priority patent/BR9808908B1/pt
Priority to ES98917598T priority patent/ES2167889T3/es
Priority to KR1019997009473A priority patent/KR100562052B1/ko
Publication of ITRM970222A1 publication Critical patent/ITRM970222A1/it
Application granted granted Critical
Publication of IT1291143B1 publication Critical patent/IT1291143B1/it
Priority to HK00102419A priority patent/HK1025562A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/255Tartaric acid
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/40Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)
IT97RM000222A 1997-04-18 1997-04-18 Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina IT1291143B1 (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT97RM000222A IT1291143B1 (it) 1997-04-18 1997-04-18 Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina
US09/402,650 US6080786A (en) 1997-04-18 1998-04-04 Solid compositions suitable for oral administration comprising L-carnitine or alkanoyl-L-carnitine choline tartrate
PCT/IT1998/000080 WO1998047857A1 (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising l-carnitine or alkanoyl-l-carnitine choline tartrate
EP98917598A EP0975581B1 (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising l-carnitine or alkanoyl-l-carnitine choline tartrate
DK98917598T DK0975581T3 (da) 1997-04-18 1998-04-08 Til oral administrering egnede faste præparater omfattende L-carnitin eller alkanoyl-L-canitincholintartrat
AT98917598T ATE208759T1 (de) 1997-04-18 1998-04-08 Feste zusammensetzungen für orale verabreichung die l-carnitin- oder alkanoyl-l- carnitin-cholin- tartrat enthalten
CA002286631A CA2286631C (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising l-carnitine or an alkanoyl-l-carnitinecholine tartrate
DE69802518T DE69802518T2 (de) 1997-04-18 1998-04-08 Feste zusammensetzungen für orale verabreichung die l-carnitin- oder alkanoyl-l- carnitin-cholin-tartrat enthalten
AU70777/98A AU731223B2 (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising L-carnitine or alkanoyl-L-carnitine choline tartrate
PT98917598T PT975581E (pt) 1997-04-18 1998-04-08 Composicoes solidas adequadas para administracao oral compreendendo tartarato de l-carnitina e colina ou de alcanoil-l-carnitina e colina
SI9830051T SI0975581T1 (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising l-carnitine or alkanoyl-l-carnitine choline tartrate
NZ500535A NZ500535A (en) 1997-04-18 1998-04-08 Solid compositions suitable for oral administration comprising L-carnitine or alkanoyl-L-carnitine choline tartrate
BRPI9808908-0A BR9808908B1 (pt) 1997-04-18 1998-04-08 sal de l-carnitina ou de alcanoil-l-carnitina, bem como composição farmacêutica ou nutricional à base do mesmo.
ES98917598T ES2167889T3 (es) 1997-04-18 1998-04-08 Composiciones solidas adecuadas para administracion oral que comprenden tartrato de l-carnitina colina o tartrato de alcanoil-l-carnitina colina.
KR1019997009473A KR100562052B1 (ko) 1997-04-18 1998-04-08 L-카르니틴 또는 알카노일-l-카르니틴 콜린 타르트레이트를 함유하는 경구 투여용 고체 조성물
JP54538898A JP4046361B2 (ja) 1997-04-18 1998-04-08 L−カルニチン又はアルカノイル−l−カルニチンコリン酒石酸塩を含む、経口投与に適した固体組成物
HK00102419A HK1025562A1 (en) 1997-04-18 2000-04-20 Solid compositions suitable for oral administration comprising l-carnitine choline tartrate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000222A IT1291143B1 (it) 1997-04-18 1997-04-18 Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina

Publications (2)

Publication Number Publication Date
ITRM970222A1 ITRM970222A1 (it) 1998-10-18
IT1291143B1 true IT1291143B1 (it) 1998-12-29

Family

ID=11404982

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000222A IT1291143B1 (it) 1997-04-18 1997-04-18 Composizioni solide atte alla somministrazione orale comprendenti l-carnitina colina tartrato o una alcanoil l-carnitina colina

Country Status (17)

Country Link
US (1) US6080786A (it)
EP (1) EP0975581B1 (it)
JP (1) JP4046361B2 (it)
KR (1) KR100562052B1 (it)
AT (1) ATE208759T1 (it)
AU (1) AU731223B2 (it)
BR (1) BR9808908B1 (it)
CA (1) CA2286631C (it)
DE (1) DE69802518T2 (it)
DK (1) DK0975581T3 (it)
ES (1) ES2167889T3 (it)
HK (1) HK1025562A1 (it)
IT (1) IT1291143B1 (it)
NZ (1) NZ500535A (it)
PT (1) PT975581E (it)
SI (1) SI0975581T1 (it)
WO (1) WO1998047857A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1306147B1 (it) 1999-05-28 2001-05-30 Biosalts Srl Derivati di principi attivi ad attivita' terapeutica e/o nutrizionalee composizioni atte alla somministrazione orale contenenti tali
IT1306186B1 (it) * 1999-09-03 2001-05-30 Biosalts Srl Sali non igroscopici di principi attivi ad attivita' terapeutica e/onutrizionale e composizioni atte alla somministrazione orale
DE19956772A1 (de) * 1999-11-25 2001-06-07 Basf Ag Verwendung von y-Butyrobetain Salzen zur Herstellung von Zubereitungen für die menschliche und tierische Ernährung
DE20321010U1 (de) * 2003-03-28 2005-12-29 Schymura, Martin Fruchtgummizusammensetzung
BR102016009579A2 (pt) * 2016-04-28 2017-10-31 Geralatex Indl E Coml Prod Agro Florestais Nutritional food supplement formulated on the basis of pulp or humid watermelon factor, modified by hydration or reidrating, also known as tapioca, used as a source of carbohydrates and nucleus for formulations for food and dietary supplementation or, still as a partial substitute of meals for athletes or practicers of physical activities, its compositions and process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1153640A (en) * 1967-04-10 1969-05-29 Soc D Etudes Prod Chimique A Carnitin Salt
FR2529545B1 (fr) * 1982-07-02 1985-05-31 Sanofi Sa Nouveaux sels de carnitine ainsi que leur procede de preparation
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
US5001117A (en) * 1989-03-07 1991-03-19 Pharmacaps, Inc. Use of lecithin to restore olfaction and taste
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
US5073376A (en) * 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine
IT1261688B (it) * 1993-05-28 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.

Also Published As

Publication number Publication date
KR20010006386A (ko) 2001-01-26
HK1025562A1 (en) 2000-11-17
ATE208759T1 (de) 2001-11-15
DE69802518D1 (de) 2001-12-20
EP0975581A1 (en) 2000-02-02
EP0975581B1 (en) 2001-11-14
JP2002512613A (ja) 2002-04-23
WO1998047857A1 (en) 1998-10-29
SI0975581T1 (en) 2002-06-30
DE69802518T2 (de) 2002-05-16
AU731223B2 (en) 2001-03-29
CA2286631A1 (en) 1998-10-29
US6080786A (en) 2000-06-27
PT975581E (pt) 2002-04-29
NZ500535A (en) 2001-03-30
BR9808908B1 (pt) 2011-02-08
DK0975581T3 (da) 2002-03-25
CA2286631C (en) 2008-07-08
BR9808908A (pt) 2000-08-01
JP4046361B2 (ja) 2008-02-13
ES2167889T3 (es) 2002-05-16
AU7077798A (en) 1998-11-13
ITRM970222A1 (it) 1998-10-18
KR100562052B1 (ko) 2006-03-17

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