ES2131543T3 - Medicion del tiempo de tromboplastina parcial activado (aptt) en una reaccion de una sola etapa. - Google Patents

Medicion del tiempo de tromboplastina parcial activado (aptt) en una reaccion de una sola etapa.

Info

Publication number
ES2131543T3
ES2131543T3 ES93110471T ES93110471T ES2131543T3 ES 2131543 T3 ES2131543 T3 ES 2131543T3 ES 93110471 T ES93110471 T ES 93110471T ES 93110471 T ES93110471 T ES 93110471T ES 2131543 T3 ES2131543 T3 ES 2131543T3
Authority
ES
Spain
Prior art keywords
aptt
time
stage reaction
measuring
activated partial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93110471T
Other languages
English (en)
Inventor
Dieter Josef
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stiftung fur Diagnostische Forschung
Original Assignee
Stiftung fur Diagnostische Forschung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stiftung fur Diagnostische Forschung filed Critical Stiftung fur Diagnostische Forschung
Application granted granted Critical
Publication of ES2131543T3 publication Critical patent/ES2131543T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA DETERMINACION DEL TIEMPO (APTT) DE TROMBOPLASTINA PARCIALMENTE ACTIVADA EN UNA REACCION DE UNA ETAPA, CARACTERIZADO PORQUE SE EMPIEZA LA DETERMINACION DEL (APTT) A TRAVES DEL CONTACTADO CON UN LIQUIDO DE MUESTRA DE UN REACTIVO, QUE CONTIENE LAS SUSTANCIAS NECESARIAS PARA LA DETERMINACION DEL (APTT) EN UNA SITUACION DE MEZCLA PREVIA. LA INVENCION SE REFIERE ADEMAS A UN REACTIVO PARA LA REALIZACION DEL PROCEDIMIENTO.
ES93110471T 1993-06-30 1993-06-30 Medicion del tiempo de tromboplastina parcial activado (aptt) en una reaccion de una sola etapa. Expired - Lifetime ES2131543T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93110471A EP0633473B1 (de) 1993-06-30 1993-06-30 Messung des aktivierten partiellen Thromboplastinzeit (APTT) in einer Einstufen-Reaktion

Publications (1)

Publication Number Publication Date
ES2131543T3 true ES2131543T3 (es) 1999-08-01

Family

ID=8213025

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93110471T Expired - Lifetime ES2131543T3 (es) 1993-06-30 1993-06-30 Medicion del tiempo de tromboplastina parcial activado (aptt) en una reaccion de una sola etapa.

Country Status (8)

Country Link
US (1) US5506146A (es)
EP (1) EP0633473B1 (es)
JP (1) JPH07151763A (es)
AT (1) ATE177536T1 (es)
DE (1) DE59309435D1 (es)
DK (1) DK0633473T3 (es)
ES (1) ES2131543T3 (es)
GR (1) GR3029654T3 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6898532B1 (en) * 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6429017B1 (en) * 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
AT405692B (de) * 1997-03-27 1999-10-25 Immuno Ag Reagens zur bestimmung der aptt
CA2362055C (en) * 1999-02-04 2010-07-20 Akzo Nobel N.V. A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6451610B1 (en) * 1999-04-14 2002-09-17 International Technidyne Corporation Method and apparatus for coagulation based assays
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
US6632678B2 (en) 2001-01-03 2003-10-14 Sienco, Inc. Method for performing activated clotting time test with reduced sensitivity to the presence of aprotinin and for assessing aprotinin sensitivity
JPWO2006129703A1 (ja) * 2005-05-31 2009-01-08 学校法人 久留米大学 活性化部分トロンボプラスチン時間の検査方法
CN101221189B (zh) * 2007-01-12 2012-08-15 上海太阳生物技术有限公司 一种用于测定活化部分凝血活酶时间aptt的体外诊断试剂盒
GB0701821D0 (en) * 2007-02-01 2007-03-14 Pentapharm Ag Diagnostic composition and its use in the determination of coagulation characteristics of a test liquid
CN101226201B (zh) * 2008-02-05 2011-05-11 长安大学 活化部分凝血活酶时间(aptt)测定试剂
JP2011133396A (ja) * 2009-12-25 2011-07-07 Sysmex Corp 活性化部分トロンボプラスチン時間測定試薬、活性化部分トロンボプラスチン時間測定方法、及び血液凝固抑制物質の有無の判定方法
JP5911345B2 (ja) * 2012-03-27 2016-04-27 シスメックス株式会社 凝固時間測定用試薬、凝固時間測定用試薬キットおよび凝固時間の測定方法
EP2877202A4 (en) 2012-07-25 2016-06-01 Biogen Ma Inc BLOOD FACTOR MONITORING TEST AND USES THEREOF
CN105445478B (zh) * 2015-11-12 2017-08-29 武汉中太生物技术有限公司 活化部分凝血活酶时间测定试剂盒及其制备方法
CN107748267B (zh) * 2017-10-13 2019-02-26 山东艾科达生物科技有限公司 一种测定活化部分凝血活酶时间（aptt）的试剂盒
CN108226540B (zh) * 2018-02-08 2020-07-03 武汉市长立生物技术有限责任公司 一种鞣花酸试剂及其配制方法与活化部分凝血活酶时间测定试剂、aptt试剂盒
JP7444572B2 (ja) * 2019-09-24 2024-03-06 シスメックス株式会社 活性化部分トロンボプラスチン時間測定用試薬及び試薬キット、並びにエラグ酸化合物の沈殿を抑制する方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4480029A (en) * 1981-04-27 1984-10-30 Baxter Travenol Laboratories, Inc. Biological indicators and their use
US4495278A (en) * 1981-04-27 1985-01-22 Baxter Travenol Laboratories, Inc. Process for making novel blood clotting enzyme compositions
US4470968A (en) * 1983-01-13 1984-09-11 Miles Laboratories, Inc. Pasteurized therapeutically active blood coagulation factor concentrates
DE3311287A1 (de) * 1983-03-28 1984-10-04 Behringwerke Ag, 3550 Marburg Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu
DE3516579A1 (de) * 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
US5086002A (en) * 1987-09-07 1992-02-04 Agen Biomedical, Ltd. Erythrocyte agglutination assay
US5055412A (en) * 1989-03-21 1991-10-08 Proksch Gary J Factor sensitive reagent for testing of blood coagulation containing ellagic acid and divalent metal ions and method of making the same
US5039617A (en) * 1989-04-20 1991-08-13 Biotrack, Inc. Capillary flow device and method for measuring activated partial thromboplastin time
IT1230744B (it) * 1989-07-07 1991-10-29 Instrumentation Lab Spa Metodo per la determinazione della attivita' funzionale della proteina s nel plasma umano.
US5091304A (en) * 1989-08-21 1992-02-25 International Technidyne Corporation Whole blood activated partial thromboplastin time test and associated apparatus
US5169786A (en) * 1989-12-19 1992-12-08 Ortho Diagnostic Systems, Inc. Method of determining levels of extrinsic and intrinsic clotting factors and protein c
US5288612A (en) * 1991-07-03 1994-02-22 The Scripps Research Institute Assay methods for detecting serum proteases, particularly activated protein C
JP3180824B2 (ja) * 1991-08-30 2001-06-25 シスメックス株式会社 血液凝固試薬

Also Published As

Publication number Publication date
DK0633473T3 (da) 1999-08-09
DE59309435D1 (de) 1999-04-15
EP0633473A1 (de) 1995-01-11
JPH07151763A (ja) 1995-06-16
EP0633473B1 (de) 1999-03-10
ATE177536T1 (de) 1999-03-15
GR3029654T3 (en) 1999-06-30
US5506146A (en) 1996-04-09

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