ES2122303T3 - Nuevos agentes antivirales. - Google Patents

Nuevos agentes antivirales.

Info

Publication number
ES2122303T3
ES2122303T3 ES94921214T ES94921214T ES2122303T3 ES 2122303 T3 ES2122303 T3 ES 2122303T3 ES 94921214 T ES94921214 T ES 94921214T ES 94921214 T ES94921214 T ES 94921214T ES 2122303 T3 ES2122303 T3 ES 2122303T3
Authority
ES
Spain
Prior art keywords
hypericin
ethyl
compounds
antiviral agents
new antiviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94921214T
Other languages
English (en)
Inventor
Yehuda Mazur
Gad Lavie
Daniel Meruelo
David Lavie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
New York University School of Medicine
Original Assignee
Yeda Research and Development Co Ltd
New York University School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd, New York University School of Medicine filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of ES2122303T3 publication Critical patent/ES2122303T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings

Abstract

NUEVOS COMPUESTOS ANTIVIRALES (INCLUIDOS ANTIRETROVIRALES) SON ESTERES DE ACIDO MONO- O DICARBOXILICO DE HIPERICINA EN LA QUE UNO O AMBOS DE LOS GRUPOS DE METILO DE HIPERICINA ESTA SUSTITUIDO POR GRUPOS DE ESTER DE ACIDO CARBOXILICO DE LA FORMULA COOR{SUP,3} EN LA QUE R{SUP,3} ES ALKILO, LA CADENA DE LA CUAL ESTA OPCIONALMENTE INTERRUMPIDA POR UNO O MAS ATOMOS DE OXIGENO O AZUFRE. R{SUP,3} ES PREFERIBLEMENTE METILO, ETILO, PROPILO, BUTILO, 2-METOXIETILO O 2-(2-METOXIETOXI)ETILO. LOS COMPUESTOS PUEDEN SER FORMULADOS EN COMPOSICIONES FARMACEUTICAS Y PUEDEN UTILIZARSE EN CUALQUIER MANERA PREVIAMENTE CONOCIDA PARA HIPERICINA.
ES94921214T 1993-05-27 1994-05-27 Nuevos agentes antivirales. Expired - Lifetime ES2122303T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/068,379 US6576784B1 (en) 1993-05-27 1993-05-27 Antiviral agents

Publications (1)

Publication Number Publication Date
ES2122303T3 true ES2122303T3 (es) 1998-12-16

Family

ID=22082194

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94921214T Expired - Lifetime ES2122303T3 (es) 1993-05-27 1994-05-27 Nuevos agentes antivirales.

Country Status (12)

Country Link
US (1) US6576784B1 (es)
EP (1) EP0702669B1 (es)
JP (1) JPH08510753A (es)
AT (1) ATE168985T1 (es)
AU (1) AU689120B2 (es)
CA (1) CA2163793C (es)
DE (1) DE69412095T2 (es)
DK (1) DK0702669T3 (es)
ES (1) ES2122303T3 (es)
GR (1) GR3027710T3 (es)
IL (1) IL109807A (es)
WO (1) WO1994027952A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121440A0 (en) 1997-07-31 1998-01-04 Yeda Res & Dev The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives
CN1308492A (zh) * 1998-07-09 2001-08-15 Cv技术公司 金丝桃素和金丝桃提取物:特效的t－型钙通道阻断剂,及其作为t－型钙通道的目标疗法的应用
DK175561B1 (da) * 1999-01-11 2004-12-06 Lego As Legetöjsbyggesæt med system til overföring af energi mellem byggeelementer
EP1040825A1 (en) * 1999-03-11 2000-10-04 K.U. Leuven Research & Development Means for diagnosing bladder carcinoma
US7195783B2 (en) 1999-07-09 2007-03-27 Fx Life Sciences International Gmbh Hypericin and hypericum extract: specific T-type calcium channel blocker, and their use as T-type calcium channel targeted therapeutics
US7037534B2 (en) * 2001-10-24 2006-05-02 Aphios Corporation Inactivation of viral infections agents by chemiluminescence activated light-sensitive compounds
US20080199458A1 (en) * 2007-01-19 2008-08-21 Jian-Er Lin Influenza prevention and treatment composition
KR102592878B1 (ko) * 2016-03-01 2023-10-20 솔리제닉스, 인크. 합성 하이페리신을 생산하기 위한 시스템 및 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93682A (en) * 1989-03-16 1996-06-18 Yeda Res & Dev Polycyclic compounds with antigypical activity are used in the manufacture of medicines and pharmaceutical preparations containing them
AU3056492A (en) 1991-11-01 1993-06-07 New York University Hypericin compositions for treating t-cell mediated diseases

Also Published As

Publication number Publication date
AU689120B2 (en) 1998-03-26
ATE168985T1 (de) 1998-08-15
EP0702669A4 (en) 1996-01-29
JPH08510753A (ja) 1996-11-12
CA2163793C (en) 2007-04-17
DE69412095D1 (de) 1998-09-03
WO1994027952A1 (en) 1994-12-08
EP0702669B1 (en) 1998-07-29
DE69412095T2 (de) 1998-12-03
EP0702669A1 (en) 1996-03-27
IL109807A (en) 1998-12-06
US6576784B1 (en) 2003-06-10
GR3027710T3 (en) 1998-11-30
IL109807A0 (en) 1994-08-26
CA2163793A1 (en) 1994-12-08
AU7202394A (en) 1994-12-20
DK0702669T3 (da) 1998-11-09

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