ES2062398T3 - Aroil-ureas. - Google Patents

Aroil-ureas.

Info

Publication number
ES2062398T3
ES2062398T3 ES90310933T ES90310933T ES2062398T3 ES 2062398 T3 ES2062398 T3 ES 2062398T3 ES 90310933 T ES90310933 T ES 90310933T ES 90310933 T ES90310933 T ES 90310933T ES 2062398 T3 ES2062398 T3 ES 2062398T3
Authority
ES
Spain
Prior art keywords
aroil
ureas
opylmethoxy
cyclop
octan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90310933T
Other languages
English (en)
Inventor
Terence James Ward
Janet Christine White
Gerald Bradley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Application granted granted Critical
Publication of ES2062398T3 publication Critical patent/ES2062398T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Removal Of Specific Substances (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

BENZAMIDA(CICLOPROPILMETOXI)-2-[CARBONIL[AMINO(IL-3-OCTAN[1.2.3 ]AZABICICLO-8-METIL-8)]]-N-(ENDO) Y SUS SALES DE ADICION DE ACIDO ACEPTABLES FARMACEUTICAMENTE SON UTILES COMO ANTAGONISTAS HT3-5, POR EJEMPLO EN EL TRATAMIENTO DE LA ANSIEDAD.
ES90310933T 1989-10-07 1990-10-05 Aroil-ureas. Expired - Lifetime ES2062398T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898922622A GB8922622D0 (en) 1989-10-07 1989-10-07 Aroylureas

Publications (1)

Publication Number Publication Date
ES2062398T3 true ES2062398T3 (es) 1994-12-16

Family

ID=10664224

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90310933T Expired - Lifetime ES2062398T3 (es) 1989-10-07 1990-10-05 Aroil-ureas.

Country Status (22)

Country Link
EP (1) EP0422846B1 (es)
JP (1) JP2960141B2 (es)
KR (1) KR100196263B1 (es)
CN (1) CN1042534C (es)
AT (1) ATE101607T1 (es)
AU (1) AU634584B2 (es)
CA (1) CA2027041C (es)
CZ (1) CZ280228B6 (es)
DE (1) DE69006675T2 (es)
DK (1) DK0422846T3 (es)
ES (1) ES2062398T3 (es)
FI (1) FI96419C (es)
GB (2) GB8922622D0 (es)
HU (1) HU204821B (es)
IE (1) IE64043B1 (es)
IL (1) IL95892A (es)
MX (1) MX22719A (es)
NZ (1) NZ235583A (es)
PT (1) PT95490B (es)
RU (2) RU1817778C (es)
SK (1) SK279469B6 (es)
ZA (1) ZA907993B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8922622D0 (en) * 1989-10-07 1989-11-22 Wyeth John & Brother Ltd Aroylureas
GB9106571D0 (en) * 1991-03-27 1991-05-15 Erba Carlo Spa Derivatives of substituted imidazol-2-one and process for their preparation
GB2269747B (en) * 1992-08-19 1996-06-05 Wyeth John & Brother Ltd Aroyl-ureas as pharmaceuticals, particularly 5-ht3 antagonists
GB9217629D0 (en) * 1992-08-19 1992-09-30 Wyeth John & Brother Ltd Aroylureas
GB9314174D0 (en) * 1993-07-08 1993-08-18 American Home Prod 5-ht3-antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63474B1 (en) * 1987-12-24 1995-04-19 Wyeth John & Brother Ltd Heterocyclic compounds
DK443489D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB8922622D0 (en) * 1989-10-07 1989-11-22 Wyeth John & Brother Ltd Aroylureas

Also Published As

Publication number Publication date
DE69006675T2 (de) 1994-05-26
MX22719A (es) 1993-09-01
CN1050875A (zh) 1991-04-24
DE69006675D1 (de) 1994-03-24
SK480890A3 (en) 1998-11-04
RU1817778C (ru) 1993-05-23
JP2960141B2 (ja) 1999-10-06
IL95892A (en) 1994-06-24
ATE101607T1 (de) 1994-03-15
HUT55391A (en) 1991-05-28
CN1042534C (zh) 1999-03-17
CZ480890A3 (en) 1995-07-12
EP0422846B1 (en) 1994-02-16
GB8922622D0 (en) 1989-11-22
KR100196263B1 (ko) 1999-06-15
CZ280228B6 (cs) 1995-12-13
NZ235583A (en) 1991-12-23
FI96419B (fi) 1996-03-15
GB2236528B (en) 1993-06-30
EP0422846A3 (en) 1991-12-04
GB2236528A (en) 1991-04-10
FI96419C (fi) 1996-06-25
SK279469B6 (sk) 1998-11-04
GB9021695D0 (en) 1990-11-21
IL95892A0 (en) 1991-07-18
KR910007871A (ko) 1991-05-30
PT95490B (pt) 1997-11-28
HU204821B (en) 1992-02-28
DK0422846T3 (da) 1994-03-14
IE903583A1 (en) 1991-04-10
CA2027041C (en) 2000-08-08
AU634584B2 (en) 1993-02-25
CA2027041A1 (en) 1991-04-08
HU906355D0 (en) 1991-04-29
RU2036923C1 (ru) 1995-06-09
IE64043B1 (en) 1995-06-28
PT95490A (pt) 1991-07-05
ZA907993B (en) 1992-06-24
FI904912A0 (fi) 1990-10-05
JPH03133986A (ja) 1991-06-07
AU6374990A (en) 1991-04-11
EP0422846A2 (en) 1991-04-17

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