ES2014187A6 - Procedimiento para preparar levo y dextro-dropropizina. - Google Patents
Procedimiento para preparar levo y dextro-dropropizina.Info
- Publication number
- ES2014187A6 ES2014187A6 ES8902707A ES8902707A ES2014187A6 ES 2014187 A6 ES2014187 A6 ES 2014187A6 ES 8902707 A ES8902707 A ES 8902707A ES 8902707 A ES8902707 A ES 8902707A ES 2014187 A6 ES2014187 A6 ES 2014187A6
- Authority
- ES
- Spain
- Prior art keywords
- dropropizine
- laevo
- dextro
- preparation
- glycidol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- PTVWPYVOOKLBCG-CYBMUJFWSA-N (2r)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol Chemical compound C1CN(C[C@@H](O)CO)CCN1C1=CC=CC=C1 PTVWPYVOOKLBCG-CYBMUJFWSA-N 0.000 title abstract 3
- 229960004722 dropropizine Drugs 0.000 abstract 2
- CTKINSOISVBQLD-GSVOUGTGSA-N (R)-Glycidol Chemical compound OC[C@@H]1CO1 CTKINSOISVBQLD-GSVOUGTGSA-N 0.000 abstract 1
- CTKINSOISVBQLD-VKHMYHEASA-N (S)-Glycidol Chemical compound OC[C@H]1CO1 CTKINSOISVBQLD-VKHMYHEASA-N 0.000 abstract 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical compound C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8821611A IT1226570B (it) | 1988-08-01 | 1988-08-01 | Procedimento di preparazione della levo- e destro-dropropizina |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2014187A6 true ES2014187A6 (es) | 1990-06-16 |
Family
ID=11184306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902707A Expired - Lifetime ES2014187A6 (es) | 1988-08-01 | 1989-07-31 | Procedimiento para preparar levo y dextro-dropropizina. |
Country Status (5)
Country | Link |
---|---|
ES (1) | ES2014187A6 (fr) |
FR (1) | FR2634765B1 (fr) |
IT (1) | IT1226570B (fr) |
LU (1) | LU87538A1 (fr) |
NL (1) | NL8901701A (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1231158B (it) * | 1989-07-20 | 1991-11-19 | Dompe Farmaceutici Spa | Procedimento per la risoluzione ottica della dropropizina. |
IT1254452B (it) * | 1992-02-14 | 1995-09-25 | Dompe Farmaceutici Spa | N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli |
IT1254993B (it) * | 1992-06-24 | 1995-10-11 | Procedimento per la preparazione degli enantiomeri della dropropizina | |
IT1318650B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | 1,3-diossolani ad attivita' antitosse. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB938646A (en) * | 1961-03-16 | 1963-10-02 | Henri Morren | New piperazine derivatives |
IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
NL8801622A (nl) * | 1988-06-25 | 1990-01-16 | Stamicarbon | Bereiding van enantiomeren van dropropizine. |
-
1988
- 1988-08-01 IT IT8821611A patent/IT1226570B/it active
-
1989
- 1989-05-18 FR FR8906484A patent/FR2634765B1/fr not_active Expired - Lifetime
- 1989-06-14 LU LU87538A patent/LU87538A1/fr unknown
- 1989-07-04 NL NL8901701A patent/NL8901701A/nl not_active Application Discontinuation
- 1989-07-31 ES ES8902707A patent/ES2014187A6/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IT8821611A0 (it) | 1988-08-01 |
IT1226570B (it) | 1991-01-24 |
NL8901701A (nl) | 1990-03-01 |
FR2634765B1 (fr) | 1994-05-27 |
LU87538A1 (fr) | 1991-02-18 |
FR2634765A1 (fr) | 1990-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20100315 |