ES2014187A6 - Procedimiento para preparar levo y dextro-dropropizina. - Google Patents

Procedimiento para preparar levo y dextro-dropropizina.

Info

Publication number
ES2014187A6
ES2014187A6 ES8902707A ES8902707A ES2014187A6 ES 2014187 A6 ES2014187 A6 ES 2014187A6 ES 8902707 A ES8902707 A ES 8902707A ES 8902707 A ES8902707 A ES 8902707A ES 2014187 A6 ES2014187 A6 ES 2014187A6
Authority
ES
Spain
Prior art keywords
dropropizine
laevo
dextro
preparation
glycidol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8902707A
Other languages
English (en)
Inventor
Carlo Polacci
Massimiliano Lussana
Alberto Gallazzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bidachem SpA
Original Assignee
Bidachem SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bidachem SpA filed Critical Bidachem SpA
Publication of ES2014187A6 publication Critical patent/ES2014187A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR LEVO- Y DEXTRO-DOPROPIZINA, EN EL QUE SE HACE REACCIONAR SELECTIVAMENTE 1-FENIL-PIPERAZINA CON (R)-GLICIDOL Y (S)-GLICIDOL, RESPECTIVAMENTE.
ES8902707A 1988-08-01 1989-07-31 Procedimiento para preparar levo y dextro-dropropizina. Expired - Lifetime ES2014187A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8821611A IT1226570B (it) 1988-08-01 1988-08-01 Procedimento di preparazione della levo- e destro-dropropizina

Publications (1)

Publication Number Publication Date
ES2014187A6 true ES2014187A6 (es) 1990-06-16

Family

ID=11184306

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8902707A Expired - Lifetime ES2014187A6 (es) 1988-08-01 1989-07-31 Procedimiento para preparar levo y dextro-dropropizina.

Country Status (5)

Country Link
ES (1) ES2014187A6 (es)
FR (1) FR2634765B1 (es)
IT (1) IT1226570B (es)
LU (1) LU87538A1 (es)
NL (1) NL8901701A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
IT1254452B (it) * 1992-02-14 1995-09-25 Dompe Farmaceutici Spa N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
IT1254993B (it) * 1992-06-24 1995-10-11 Procedimento per la preparazione degli enantiomeri della dropropizina
IT1318650B1 (it) * 2000-07-28 2003-08-27 Dompe Spa 1,3-diossolani ad attivita' antitosse.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB938646A (en) * 1961-03-16 1963-10-02 Henri Morren New piperazine derivatives
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.

Also Published As

Publication number Publication date
NL8901701A (nl) 1990-03-01
FR2634765B1 (fr) 1994-05-27
IT8821611A0 (it) 1988-08-01
FR2634765A1 (fr) 1990-02-02
LU87538A1 (fr) 1991-02-18
IT1226570B (it) 1991-01-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100315