EP0777741A4 - BIOSENSOR AND METHOD FOR THE ELECTROPHOTOCHEMICAL LUMINESCENCE DETECTION OF NUCLEIC ACIDS ADSORBED ON A SOLID SURFACE - Google Patents
BIOSENSOR AND METHOD FOR THE ELECTROPHOTOCHEMICAL LUMINESCENCE DETECTION OF NUCLEIC ACIDS ADSORBED ON A SOLID SURFACEInfo
- Publication number
- EP0777741A4 EP0777741A4 EP95930881A EP95930881A EP0777741A4 EP 0777741 A4 EP0777741 A4 EP 0777741A4 EP 95930881 A EP95930881 A EP 95930881A EP 95930881 A EP95930881 A EP 95930881A EP 0777741 A4 EP0777741 A4 EP 0777741A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- biosensor
- nucleic acid
- solid surface
- chemiluminescent detection
- acid adsorbed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29663094A | 1994-08-26 | 1994-08-26 | |
| US296630 | 1994-08-26 | ||
| PCT/US1995/010630 WO1996006946A1 (en) | 1994-08-26 | 1995-08-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0777741A1 EP0777741A1 (en) | 1997-06-11 |
| EP0777741A4 true EP0777741A4 (en) | 1999-01-13 |
Family
ID=23142843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP95930881A Withdrawn EP0777741A4 (en) | 1994-08-26 | 1995-08-25 | BIOSENSOR AND METHOD FOR THE ELECTROPHOTOCHEMICAL LUMINESCENCE DETECTION OF NUCLEIC ACIDS ADSORBED ON A SOLID SURFACE |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0777741A4 (ja) |
| JP (1) | JPH10509025A (ja) |
| AU (1) | AU703344B2 (ja) |
| CA (1) | CA2198489A1 (ja) |
| WO (1) | WO1996006946A1 (ja) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786141A (en) * | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| CA2213854C (en) * | 1995-03-10 | 2010-08-10 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| FR2762013B1 (fr) | 1997-04-09 | 1999-06-04 | Cis Bio Int | Systemes de detection d'hybridation d'acides nucleiques, leur procede de preparation et leurs utilisations |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| DE60041072D1 (de) | 1999-07-26 | 2009-01-22 | Clinical Micro Sensors Inc | Em nachweis |
| US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
| JP2003516165A (ja) * | 1999-12-09 | 2003-05-13 | モトローラ・インコーポレイテッド | 核酸反応の電気的検出に関する方法および組成物 |
| US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
| US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
| WO2005016115A2 (en) | 2003-01-23 | 2005-02-24 | Montana State University | Biosensors utilizing dendrimer-immobilized ligands and their use thereof |
| US7741033B2 (en) * | 2003-05-13 | 2010-06-22 | Trustees Of Boston College | Electrocatalytic nucleic acid hybridization detection |
| ATE445715T1 (de) | 2003-05-13 | 2009-10-15 | Trustees Boston College | Elektrokatalytischer nukleinsäurehybridisierungsnachweis |
| WO2006075497A1 (ja) * | 2004-12-21 | 2006-07-20 | Kyoto University | プローブユニット、ヌクレオチド領域の同定装置、及びヌクレオチド領域の同定方法 |
| ES2517919T3 (es) | 2008-09-02 | 2014-11-04 | The Governing Council Of The University Of Toronto | Microelectrodos nanoestructurados y dispositivos de biodetección que los incorporan |
| RU2606852C2 (ru) | 2011-01-11 | 2017-01-10 | Дзе Гавернинг Каунсил Оф Дзе Юниверсити Оф Торонто | Способ детекции белков |
| ES2799422T3 (es) | 2011-03-10 | 2020-12-17 | General Atomics | Dispositivos y métodos de diagnóstico y preparación de muestras |
| CN107923911A (zh) | 2015-08-20 | 2018-04-17 | 豪夫迈·罗氏有限公司 | 使用聚乙二醇化分析物特异性结合剂的基于颗粒的免疫测定法 |
| BR112018017336A2 (pt) | 2016-03-07 | 2018-12-26 | Hoffmann La Roche | método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão |
| ES2865511T3 (es) | 2017-02-02 | 2021-10-15 | Hoffmann La Roche | Inmunoanálisis que usa al menos dos agentes de unión específica a analito pegilado |
| JP2021522192A (ja) | 2018-04-18 | 2021-08-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 新規抗チミジンキナーゼ抗体 |
| EP3844503B1 (en) | 2018-08-31 | 2024-05-29 | F. Hoffmann-La Roche AG | Thymidine kinase (tk-1) in prognostic indices for dlbcl |
| WO2021013786A1 (en) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis |
| EP4004554A1 (en) | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
| CN114144674A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | P物质作为用于子宫内膜异位症的非侵入性诊断的血液生物标志物 |
| CN114144673A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a8作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
| JP7315781B2 (ja) | 2019-07-22 | 2023-07-26 | エフ． ホフマン－ラ ロシュ アーゲー | 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ１２ |
| BR112022009371A2 (pt) | 2019-11-15 | 2022-08-09 | Hoffmann La Roche | Métodos para determinar a quantidade ou concentração de um ou mais analitos antibióticos, tubos de amostragem, usos de um reagente de derivatização nucleofílica e analito antibiótico |
| CN111272742B (zh) * | 2020-03-06 | 2022-11-08 | 安徽大学 | 基于金属有机凝胶复合材料和金属有机框架的电致化学发光传感器及其制备和检测方法 |
| US20230406909A1 (en) | 2020-11-02 | 2023-12-21 | Roche Diagnostics Operations, Inc. | Sars-cov-2 nucleocapsid antibodies |
| WO2022207628A1 (en) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf as blood biomarker for the non-invasive diagnosis of endometriosis |
| CN117099001A (zh) | 2021-04-01 | 2023-11-21 | 豪夫迈·罗氏有限公司 | Psp94作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
| WO2022243210A1 (en) | 2021-05-17 | 2022-11-24 | F. Hoffmann-La Roche Ag | sFRP4 AS BLOOD BIOMARKER FOR THE NON-INVASIVE DIAGNOSIS OF ADENOMYOSIS |
| WO2023072904A1 (en) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Monoclonal antibodies specific for sars-cov-2 rbd |
| WO2023131594A1 (en) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm) |
| WO2023247752A1 (en) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Method for diagnosing endometriosis and for classifying the stage of endometriosis |
| WO2024017982A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017985A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017983A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| CN115414930B (zh) * | 2022-08-26 | 2023-10-31 | 重庆医科大学 | Ru(bpy)32+阳极或阴极共反应物及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1258580A (ja) * | 1967-12-28 | 1971-12-30 | ||
| US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5124022A (en) * | 1989-08-23 | 1992-06-23 | Aluminum Company Of America | Electrolytic capacitor and method of making same |
| US5019343A (en) * | 1989-12-15 | 1991-05-28 | W. R. Grace & Co.-Conn. | Control of corrosion in aqueous systems using certain phosphonomethyl amines |
| US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
-
1995
- 1995-08-25 JP JP8508822A patent/JPH10509025A/ja active Pending
- 1995-08-25 CA CA002198489A patent/CA2198489A1/en not_active Abandoned
- 1995-08-25 WO PCT/US1995/010630 patent/WO1996006946A1/en not_active Application Discontinuation
- 1995-08-25 AU AU34103/95A patent/AU703344B2/en not_active Ceased
- 1995-08-25 EP EP95930881A patent/EP0777741A4/en not_active Withdrawn
Non-Patent Citations (2)
| Title |
|---|
| No further relevant documents disclosed * |
| See also references of WO9606946A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2198489A1 (en) | 1996-03-07 |
| EP0777741A1 (en) | 1997-06-11 |
| JPH10509025A (ja) | 1998-09-08 |
| AU3410395A (en) | 1996-03-22 |
| WO1996006946A1 (en) | 1996-03-07 |
| AU703344B2 (en) | 1999-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19970307 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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| AX | Request for extension of the european patent |
Free format text: LT PAYMENT 970307;LV PAYMENT 970307;SI PAYMENT 970307 |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: IGEN INTERNATIONAL, INC. |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 19981202 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
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| 17Q | First examination report despatched |
Effective date: 19990105 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20000718 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 19981105 Year of fee payment: 4 |