EP0777741A4 - Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface - Google Patents
Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surfaceInfo
- Publication number
- EP0777741A4 EP0777741A4 EP95930881A EP95930881A EP0777741A4 EP 0777741 A4 EP0777741 A4 EP 0777741A4 EP 95930881 A EP95930881 A EP 95930881A EP 95930881 A EP95930881 A EP 95930881A EP 0777741 A4 EP0777741 A4 EP 0777741A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- biosensor
- nucleic acid
- solid surface
- chemiluminescent detection
- acid adsorbed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29663094A | 1994-08-26 | 1994-08-26 | |
| US296630 | 1994-08-26 | ||
| PCT/US1995/010630 WO1996006946A1 (en) | 1994-08-26 | 1995-08-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0777741A1 EP0777741A1 (en) | 1997-06-11 |
| EP0777741A4 true EP0777741A4 (en) | 1999-01-13 |
Family
ID=23142843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP95930881A Withdrawn EP0777741A4 (en) | 1994-08-26 | 1995-08-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0777741A4 (en) |
| JP (1) | JPH10509025A (en) |
| AU (1) | AU703344B2 (en) |
| CA (1) | CA2198489A1 (en) |
| WO (1) | WO1996006946A1 (en) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786141A (en) * | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| WO1996028538A1 (en) * | 1995-03-10 | 1996-09-19 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6140045A (en) * | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| FR2762013B1 (en) * | 1997-04-09 | 1999-06-04 | Cis Bio Int | DETECTION SYSTEMS FOR NUCLEIC ACID HYBRIDIZATION, PREPARATION METHOD THEREOF AND USES THEREOF |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| US7935481B1 (en) | 1999-07-26 | 2011-05-03 | Osmetech Technology Inc. | Sequence determination of nucleic acids using electronic detection |
| US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
| CA2393733A1 (en) * | 1999-12-09 | 2001-06-14 | Motorola, Inc. | Methods and compositions relating to electrical detection of nucleic acid reactions |
| US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
| US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
| US7138121B2 (en) | 2003-01-23 | 2006-11-21 | Spangler Brenda D | Biosensors utilizing dendrimer-immobilized ligands and there use thereof |
| US7741033B2 (en) * | 2003-05-13 | 2010-06-22 | Trustees Of Boston College | Electrocatalytic nucleic acid hybridization detection |
| ATE445715T1 (en) | 2003-05-13 | 2009-10-15 | Trustees Boston College | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION |
| JPWO2006075497A1 (en) * | 2004-12-21 | 2008-06-12 | 国立大学法人京都大学 | Probe unit, nucleotide region identification apparatus, and nucleotide region identification method |
| ES2517919T3 (en) | 2008-09-02 | 2014-11-04 | The Governing Council Of The University Of Toronto | Nanostructured microelectrodes and biodetection devices that incorporate them |
| EP2663857B1 (en) | 2011-01-11 | 2018-12-12 | The Governing Council Of The University Of Toronto | Protein detection method |
| WO2012122564A2 (en) | 2011-03-10 | 2012-09-13 | Xagenic, Inc. | Diagnostic and sample preparation devices and methods |
| BR112018001956A2 (en) | 2015-08-20 | 2018-09-11 | Hoffmann La Roche | ? analyte measurement method and kit? |
| BR112018017336A2 (en) | 2016-03-07 | 2018-12-26 | Hoffmann La Roche | in vitro method for detecting a p53 antibody (anti-p53 antibody) in a sample and fusion polypeptide |
| EP3577460B1 (en) | 2017-02-02 | 2021-01-20 | Roche Diagnostics GmbH | Immunoassay using at least two pegylated analyte-specific binding agents |
| CN111936522A (en) | 2018-04-18 | 2020-11-13 | 豪夫迈·罗氏有限公司 | Novel anti-thymidine kinase antibodies |
| EP3844503A1 (en) | 2018-08-31 | 2021-07-07 | F. Hoffmann-La Roche AG | Thymidine kinase (tk-1) in prognostic indices for dlbcl |
| CN114144675A (en) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100A9 as a blood biomarker for non-invasive diagnosis of endometriosis |
| CN114144671A (en) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100A12 as a blood biomarker for the non-invasive diagnosis of endometriosis |
| EP4004555A1 (en) | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis |
| CN114144674A (en) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | Substance P as a blood biomarker for the non-invasive diagnosis of endometriosis |
| KR20220024782A (en) | 2019-07-22 | 2022-03-03 | 에프. 호프만-라 로슈 아게 | S100A8 as a blood biomarker for non-invasive diagnosis of endometriosis |
| KR20220100883A (en) | 2019-11-15 | 2022-07-18 | 에프. 호프만-라 로슈 아게 | Derivatization of Beta-Lactam Antibiotics for Mass Spectrometry Determination of Patient Samples |
| CN111272742B (en) * | 2020-03-06 | 2022-11-08 | 安徽大学 | Electrochemiluminescence sensor based on metal organic gel composite material and metal organic framework and preparation and detection methods thereof |
| US20230406909A1 (en) | 2020-11-02 | 2023-12-21 | Roche Diagnostics Operations, Inc. | Sars-cov-2 nucleocapsid antibodies |
| WO2022207628A1 (en) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf as blood biomarker for the non-invasive diagnosis of endometriosis |
| JP2024511867A (en) | 2021-04-01 | 2024-03-15 | エフ． ホフマン－ラ ロシュ アーゲー | PSP94 as a blood biomarker for non-invasive diagnosis of endometriosis |
| CN117337394A (en) | 2021-05-17 | 2024-01-02 | 豪夫迈·罗氏有限公司 | sFRP4 as a blood biomarker for non-invasive diagnosis of adenomyosis |
| WO2023072904A1 (en) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Monoclonal antibodies specific for sars-cov-2 rbd |
| WO2023131594A1 (en) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm) |
| WO2023247752A1 (en) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Method for diagnosing endometriosis and for classifying the stage of endometriosis |
| WO2024017985A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017983A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017982A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| CN115414930B (en) * | 2022-08-26 | 2023-10-31 | 重庆医科大学 | Ru(bpy) 32+ Anode or cathode coreactant and method for producing same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1258580A (en) * | 1967-12-28 | 1971-12-30 | ||
| US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5124022A (en) * | 1989-08-23 | 1992-06-23 | Aluminum Company Of America | Electrolytic capacitor and method of making same |
| US5019343A (en) * | 1989-12-15 | 1991-05-28 | W. R. Grace & Co.-Conn. | Control of corrosion in aqueous systems using certain phosphonomethyl amines |
| US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
-
1995
- 1995-08-25 EP EP95930881A patent/EP0777741A4/en not_active Withdrawn
- 1995-08-25 JP JP8508822A patent/JPH10509025A/en active Pending
- 1995-08-25 AU AU34103/95A patent/AU703344B2/en not_active Ceased
- 1995-08-25 WO PCT/US1995/010630 patent/WO1996006946A1/en not_active Application Discontinuation
- 1995-08-25 CA CA002198489A patent/CA2198489A1/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| No further relevant documents disclosed * |
| See also references of WO9606946A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU703344B2 (en) | 1999-03-25 |
| AU3410395A (en) | 1996-03-22 |
| JPH10509025A (en) | 1998-09-08 |
| WO1996006946A1 (en) | 1996-03-07 |
| CA2198489A1 (en) | 1996-03-07 |
| EP0777741A1 (en) | 1997-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19970307 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
| AX | Request for extension of the european patent |
Free format text: LT PAYMENT 970307;LV PAYMENT 970307;SI PAYMENT 970307 |
|
| RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: IGEN INTERNATIONAL, INC. |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 19981202 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
| 17Q | First examination report despatched |
Effective date: 19990105 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20000718 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 19981105 Year of fee payment: 4 |