EE05155B1 - Meetod optiliselt aktiivsete antratskliinide snteesimiseks - Google Patents

Meetod optiliselt aktiivsete antratskliinide snteesimiseks

Info

Publication number
EE05155B1
EE05155B1 EEP200300180A EEP200300180A EE05155B1 EE 05155 B1 EE05155 B1 EE 05155B1 EE P200300180 A EEP200300180 A EE P200300180A EE P200300180 A EEP200300180 A EE P200300180A EE 05155 B1 EE05155 B1 EE 05155B1
Authority
EE
Estonia
Prior art keywords
synthesis
optically active
clinics
anthracite
active anthracite
Prior art date
Application number
EEP200300180A
Other languages
English (en)
Inventor
Di Bugno Cristina
D'arata Fabio
Ramacciotti Alessio
Crotti Paolo
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of EE200300180A publication Critical patent/EE200300180A/et
Publication of EE05155B1 publication Critical patent/EE05155B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Input From Keyboards Or The Like (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP200300180A 2000-11-16 2001-11-15 Meetod optiliselt aktiivsete antratskliinide snteesimiseks EE05155B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000FI000237A IT1317106B1 (it) 2000-11-16 2000-11-16 Processo per la sintesi di antracicline otticamente attive.
PCT/EP2001/013217 WO2002040496A1 (en) 2000-11-16 2001-11-15 Process for the synthesis of optically active anthracyclines

Publications (2)

Publication Number Publication Date
EE200300180A EE200300180A (et) 2003-06-16
EE05155B1 true EE05155B1 (et) 2009-04-15

Family

ID=11441998

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300180A EE05155B1 (et) 2000-11-16 2001-11-15 Meetod optiliselt aktiivsete antratskliinide snteesimiseks

Country Status (21)

Country Link
US (1) US6921841B2 (et)
EP (1) EP1335927B1 (et)
JP (1) JP4359043B2 (et)
KR (1) KR100821795B1 (et)
CN (1) CN1249071C (et)
AT (1) ATE333460T1 (et)
AU (1) AU2002214054A1 (et)
BR (1) BRPI0115250B8 (et)
CA (1) CA2429136C (et)
CY (1) CY1106182T1 (et)
DE (1) DE60121615T2 (et)
DK (1) DK1335927T3 (et)
EE (1) EE05155B1 (et)
ES (1) ES2267834T3 (et)
IT (1) IT1317106B1 (et)
MX (1) MXPA03004188A (et)
PL (1) PL212720B1 (et)
PT (1) PT1335927E (et)
RS (1) RS50465B (et)
RU (1) RU2286994C2 (et)
WO (1) WO2002040496A1 (et)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4116981A (en) 1977-05-02 1978-09-26 Yuh-Geng Tsay 5,12-epoxy-naphthacene-6,11-dione derivatives
US4405713A (en) * 1981-12-28 1983-09-20 Hoffmann-La Roche Inc. Process for the preparation of optically active anthracycline glycosides A and B
JPS62132838A (ja) * 1985-12-03 1987-06-16 Sumitomo Pharmaceut Co Ltd テトラヒドロナフタセン誘導体の製造法

Also Published As

Publication number Publication date
ATE333460T1 (de) 2006-08-15
CA2429136C (en) 2011-03-29
AU2002214054A1 (en) 2002-05-27
WO2002040496A1 (en) 2002-05-23
PL361618A1 (en) 2004-10-04
CN1474827A (zh) 2004-02-11
CN1249071C (zh) 2006-04-05
PT1335927E (pt) 2006-11-30
EP1335927B1 (en) 2006-07-19
RU2286994C2 (ru) 2006-11-10
JP2004513952A (ja) 2004-05-13
ES2267834T3 (es) 2007-03-16
RS50465B (sr) 2010-03-02
CY1106182T1 (el) 2011-06-08
DK1335927T3 (da) 2006-11-20
JP4359043B2 (ja) 2009-11-04
BR0115250A (pt) 2003-08-12
BRPI0115250B8 (pt) 2021-05-25
KR100821795B1 (ko) 2008-04-11
IT1317106B1 (it) 2003-05-26
DE60121615D1 (de) 2006-08-31
EP1335927A1 (en) 2003-08-20
ITFI20000237A1 (it) 2002-05-16
KR20030055306A (ko) 2003-07-02
PL212720B1 (pl) 2012-11-30
CA2429136A1 (en) 2002-05-23
DE60121615T2 (de) 2007-08-09
BR0115250B1 (pt) 2015-01-06
YU37303A (sh) 2006-05-25
EE200300180A (et) 2003-06-16
US20040029819A1 (en) 2004-02-12
MXPA03004188A (es) 2003-09-22
US6921841B2 (en) 2005-07-26

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231