ECSP088219A - Nueva sal i - Google Patents
Nueva sal iInfo
- Publication number
- ECSP088219A ECSP088219A EC2008008219A ECSP088219A ECSP088219A EC SP088219 A ECSP088219 A EC SP088219A EC 2008008219 A EC2008008219 A EC 2008008219A EC SP088219 A ECSP088219 A EC SP088219A EC SP088219 A ECSP088219 A EC SP088219A
- Authority
- EC
- Ecuador
- Prior art keywords
- solvate
- new salt
- salt
- chlorobenzyl
- piperidin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
La invención provee benzoato de N-{2-[((2S)-3-{[1-(4-clorobencil)piperidin-4-il]amino}-2-hidroxi-2-metil-propil)oxi]-4-hidroxifenil}acetamida o un solvato del mismo, composiciones farmacéuticas que contienen la sal o el solvato y el uso de la sal o del solvato en terapia.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0501768 | 2005-08-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088219A true ECSP088219A (es) | 2008-03-26 |
Family
ID=37708911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008219A ECSP088219A (es) | 2005-08-02 | 2008-02-25 | Nueva sal i |
Country Status (18)
Country | Link |
---|---|
US (1) | US8148405B2 (es) |
EP (1) | EP1912943A1 (es) |
JP (1) | JP2009503064A (es) |
KR (1) | KR20080031369A (es) |
CN (1) | CN101238103A (es) |
AR (1) | AR055365A1 (es) |
AU (1) | AU2006276344B2 (es) |
BR (1) | BRPI0614634A2 (es) |
CA (1) | CA2617403A1 (es) |
EC (1) | ECSP088219A (es) |
IL (1) | IL188474A0 (es) |
MX (1) | MX2008001113A (es) |
NO (1) | NO20081080L (es) |
RU (1) | RU2417220C2 (es) |
TW (1) | TW200738634A (es) |
UY (1) | UY29714A1 (es) |
WO (1) | WO2007015666A1 (es) |
ZA (1) | ZA200800515B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR028948A1 (es) * | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
WO2008100202A1 (en) * | 2007-02-14 | 2008-08-21 | Astrazeneca Ab | A 2-f luorobenzoate salt and a 2, 6-dif luorobenzoate salt of n-{5-chloro-2- [ ( (2s) -3-{ [1- (4-chlorobenzyl)piperidin-4- yl ] amino } - 2 - hydroxy- 2 -me t hylpr opyl ) oxy] - 4 - hydroxyphenyl } acetamide |
GB0814729D0 (en) * | 2008-08-12 | 2008-09-17 | Argenta Discovery Ltd | New combination |
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FR2190430A1 (en) | 1972-06-29 | 1974-02-01 | Ferlux | N-aminomethylhydroxamic acids - with antiinflammatory activity pre-pared by Mannich reaction |
US3818017A (en) | 1973-01-04 | 1974-06-18 | Janssen Pharmaceutica Nv | 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds |
US3894030A (en) | 1973-01-04 | 1975-07-08 | Janssen Pharmaceutica Nv | 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds |
US4166119A (en) | 1978-04-14 | 1979-08-28 | American Hoechst Corporation | Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines |
WO1980000152A1 (en) | 1978-07-03 | 1980-02-07 | Sandoz Ag | 3-aminopropoxy-aryl derivates,preparation and use thereof |
US4264613A (en) | 1979-08-01 | 1981-04-28 | Science Union Et Cie, Societe Francaise De Recherche Medicale | Piperidylbenzimidazolinone compounds |
FR2469411A1 (fr) | 1979-11-15 | 1981-05-22 | Science Union & Cie | Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
EP0095454A3 (de) | 1982-05-13 | 1985-04-03 | Gerot-Pharmazeutika Gesellschaft m.b.H. | Neue kernsubstituierte Pyrogallol-Derivate |
JPS59222484A (ja) | 1983-06-02 | 1984-12-14 | Kowa Co | テトラヒドロナフチルカルボン酸フエニルエステル誘導体 |
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US5614533A (en) | 1987-03-13 | 1997-03-25 | Bio-Mega/Boehringer Ingelheim Research, Inc. | Substituted pipecolinic acid derivatives as HIV protease inhibitors |
DE3723648A1 (de) | 1987-07-17 | 1989-01-26 | Sandoz Ag | Indol-derivate, ihre herstellung und sie enthaltende arzneimittel |
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SE9003057D0 (sv) | 1990-09-26 | 1990-09-26 | Astra Ab | New process |
ES2027897A6 (es) | 1991-01-24 | 1992-06-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados de la difenilmetilpiperacina. |
IL105716A0 (en) | 1992-06-08 | 1993-09-22 | Richter Gedeon Vegyeszet | Aminopropanol derivatives,their preparation and pharmaceutical compositions containing them |
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US5614523A (en) | 1995-01-17 | 1997-03-25 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5741789A (en) | 1995-01-17 | 1998-04-21 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5576321A (en) | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
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EP1553085A1 (en) | 1997-11-18 | 2005-07-13 | Teijin Limited | Cyclic amine derivatives and their use as drugs |
DE19755268A1 (de) | 1997-12-12 | 1999-06-17 | Merck Patent Gmbh | Benzamidinderivate |
FR2780057B1 (fr) | 1998-06-18 | 2002-09-13 | Sanofi Sa | Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant |
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GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
SE9900833D0 (sv) | 1999-03-09 | 1999-03-09 | Astra Ab | Novel combination |
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WO2002004434A1 (en) | 2000-07-07 | 2002-01-17 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as vascular damaging agents |
RU2003103603A (ru) | 2000-07-07 | 2004-08-20 | Энджиоджен Фармасьютикалз Лимитед (Gb) | Производные колхинола в качестве ингибиторов ангиогенеза |
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GB0021670D0 (en) * | 2000-09-04 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
GB0029562D0 (en) | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
GB2373186A (en) | 2001-02-23 | 2002-09-18 | Astrazeneca Ab | Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation |
AR035230A1 (es) | 2001-03-19 | 2004-05-05 | Astrazeneca Ab | Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos |
ATE381537T1 (de) | 2001-03-22 | 2008-01-15 | Glaxo Group Ltd | Formanilid-derivative als beta2-adrenorezeptor- agonisten |
GB0107228D0 (en) | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
SE0101038D0 (sv) | 2001-03-23 | 2001-03-23 | Astrazeneca Ab | Novel compounds |
GB0108046D0 (en) | 2001-03-30 | 2001-05-23 | Astrazeneca Ab | Chemical compounds |
JP4261914B2 (ja) | 2001-04-27 | 2009-05-13 | 田辺三菱製薬株式会社 | 新規ベンジルピペリジン化合物 |
SE0104251D0 (sv) * | 2001-12-14 | 2001-12-14 | Astrazeneca Ab | Novel compounds |
TW200303304A (en) | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
WO2005013993A1 (en) * | 2003-07-29 | 2005-02-17 | Boehringer Ingelheim International Gmbh | Medicaments comprising pde iv inhibitors and an anticholinergic for treating respiratory disorders |
CN101407514B (zh) * | 2003-11-03 | 2013-05-29 | 贝林格尔.英格海姆国际有限公司 | 噻托铵盐、包含噻托铵盐的药物制剂及其用途 |
EP1912942A1 (en) | 2005-08-01 | 2008-04-23 | AstraZeneca AB | Novel piperidine derivatives as chemokine receptor modulators useful for the treatment of respiratory diseases. |
TW200738635A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200734305A (en) | 2005-08-02 | 2007-09-16 | Astrazeneca Ab | New salt III |
CA2620281A1 (en) | 2005-08-26 | 2007-03-01 | Astrazeneca Ab | A combination of compounds, which can be used in the treatment of respiratory diseases, especially chronic obstructive pulmonary disease (copd) and asthma |
TW200744612A (en) | 2005-08-26 | 2007-12-16 | Astrazeneca Ab | New combination |
TW200800895A (en) | 2005-11-02 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
US20100041905A1 (en) | 2006-07-18 | 2010-02-18 | Astrazeneca Ab | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl |
-
2006
- 2006-07-25 TW TW095127078A patent/TW200738634A/zh unknown
- 2006-07-31 KR KR1020087002808A patent/KR20080031369A/ko not_active Application Discontinuation
- 2006-07-31 JP JP2008524932A patent/JP2009503064A/ja active Pending
- 2006-07-31 CA CA002617403A patent/CA2617403A1/en not_active Abandoned
- 2006-07-31 UY UY29714A patent/UY29714A1/es unknown
- 2006-07-31 AU AU2006276344A patent/AU2006276344B2/en not_active Ceased
- 2006-07-31 BR BRPI0614634-1A patent/BRPI0614634A2/pt not_active IP Right Cessation
- 2006-07-31 MX MX2008001113A patent/MX2008001113A/es active IP Right Grant
- 2006-07-31 RU RU2008105972/04A patent/RU2417220C2/ru not_active IP Right Cessation
- 2006-07-31 EP EP06769590A patent/EP1912943A1/en not_active Withdrawn
- 2006-07-31 WO PCT/SE2006/000920 patent/WO2007015666A1/en active Application Filing
- 2006-07-31 US US11/997,500 patent/US8148405B2/en not_active Expired - Fee Related
- 2006-07-31 CN CNA2006800284952A patent/CN101238103A/zh active Pending
- 2006-08-02 AR ARP060103358A patent/AR055365A1/es unknown
-
2007
- 2007-12-27 IL IL188474A patent/IL188474A0/en unknown
-
2008
- 2008-01-17 ZA ZA200800515A patent/ZA200800515B/xx unknown
- 2008-02-25 EC EC2008008219A patent/ECSP088219A/es unknown
- 2008-02-29 NO NO20081080A patent/NO20081080L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AR055365A1 (es) | 2007-08-22 |
US8148405B2 (en) | 2012-04-03 |
MX2008001113A (es) | 2008-03-11 |
US20080227817A1 (en) | 2008-09-18 |
KR20080031369A (ko) | 2008-04-08 |
ZA200800515B (en) | 2008-12-31 |
WO2007015666A1 (en) | 2007-02-08 |
CN101238103A (zh) | 2008-08-06 |
RU2008105972A (ru) | 2009-09-10 |
BRPI0614634A2 (pt) | 2011-04-12 |
JP2009503064A (ja) | 2009-01-29 |
NO20081080L (no) | 2008-02-29 |
AU2006276344A1 (en) | 2007-02-08 |
AU2006276344B2 (en) | 2010-10-07 |
EP1912943A1 (en) | 2008-04-23 |
IL188474A0 (en) | 2008-04-13 |
UY29714A1 (es) | 2007-02-28 |
TW200738634A (en) | 2007-10-16 |
CA2617403A1 (en) | 2007-02-08 |
RU2417220C2 (ru) | 2011-04-27 |
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