EA201692554A1 - Менингококковые вакцины - Google Patents

Менингококковые вакцины

Info

Publication number
EA201692554A1
EA201692554A1 EA201692554A EA201692554A EA201692554A1 EA 201692554 A1 EA201692554 A1 EA 201692554A1 EA 201692554 A EA201692554 A EA 201692554A EA 201692554 A EA201692554 A EA 201692554A EA 201692554 A1 EA201692554 A1 EA 201692554A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vaccines
menicococcy
alleles
dose
reducing
Prior art date
Application number
EA201692554A
Other languages
English (en)
Other versions
EA038940B1 (ru
Inventor
Алессиа Бьольки
Брунелла Брунелли
Марциа Моника Джульяни
Вега Мазиньяни
Original Assignee
Глаксосмитклайн Байолоджикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Байолоджикалс С.А. filed Critical Глаксосмитклайн Байолоджикалс С.А.
Publication of EA201692554A1 publication Critical patent/EA201692554A1/ru
Publication of EA038940B1 publication Critical patent/EA038940B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Менингококковые вакцины могут быть улучшены посредством включения совокупности аллелей или вариантов fHbp для обеспечения более широкого покрытия разнообразия, известного для данного белка, и/или посредством уменьшения количества OMV-компонента в каждой дозе.
EA201692554A 2014-07-17 2015-07-16 Менингококковые вакцины EA038940B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14177563 2014-07-17
PCT/EP2015/066229 WO2016008961A1 (en) 2014-07-17 2015-07-16 Meningococcus vaccines

Publications (2)

Publication Number Publication Date
EA201692554A1 true EA201692554A1 (ru) 2017-07-31
EA038940B1 EA038940B1 (ru) 2021-11-12

Family

ID=51178811

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201692554A EA038940B1 (ru) 2014-07-17 2015-07-16 Менингококковые вакцины

Country Status (15)

Country Link
US (2) US11707513B2 (ru)
EP (1) EP3169358A1 (ru)
JP (2) JP6687597B2 (ru)
KR (2) KR20230012100A (ru)
CN (2) CN113827712A (ru)
AR (1) AR101225A1 (ru)
AU (2) AU2015289193A1 (ru)
BE (1) BE1022878B1 (ru)
BR (1) BR112017000519A2 (ru)
CA (1) CA2954729C (ru)
EA (1) EA038940B1 (ru)
IL (1) IL249823B (ru)
MX (1) MX2017000775A (ru)
SG (2) SG11201610946YA (ru)
WO (1) WO2016008961A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS61246B1 (sr) 2014-02-28 2021-01-29 Glaxosmithkline Biologicals Sa Modifikovani meningokokni fhbp polipeptidi
EA038940B1 (ru) * 2014-07-17 2021-11-12 Глаксосмитклайн Байолоджикалс С.А. Менингококковые вакцины
CN106795208A (zh) 2014-07-17 2017-05-31 葛兰素史密丝克莱恩生物有限公司 修饰的脑膜炎球菌fHbp多肽
WO2017075189A1 (en) * 2015-10-27 2017-05-04 University Of Massachusetts Factor h-fc immunotherapy
CN107151270B (zh) * 2017-03-22 2018-07-31 武汉博沃生物科技有限公司 重组ΔfHbp-NadA融合蛋白载体及其制备方法和应用
CN108939061A (zh) * 2018-08-03 2018-12-07 北京智飞绿竹生物制药有限公司 一种多组分b群脑膜炎球菌疫苗及其制备方法
EP3607967A1 (en) * 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
US11014736B2 (en) 2019-04-18 2021-05-25 Altria Client Services Llc Sliding packs with flip top hinged lids
CN110804101A (zh) * 2019-11-08 2020-02-18 苏州微超生物科技有限公司 B群脑膜炎球菌相关融合蛋白、疫苗及其制备方法与应用
EP4065595A4 (en) * 2019-11-25 2023-12-20 Griffith University IMMUNOGENE PROTEIN AGAINST GONOCOCCAL INFECTION
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747137B1 (en) 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
US6551795B1 (en) 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
ES2507100T3 (es) * 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
GB0227346D0 (en) * 2002-11-22 2002-12-31 Chiron Spa 741
GB0419408D0 (en) 2004-09-01 2004-10-06 Chiron Srl 741 chimeric polypeptides
GB0419627D0 (en) * 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
CN103002910A (zh) 2010-03-10 2013-03-27 葛兰素史密丝克莱恩生物有限公司 疫苗组合物
BR112012024348B1 (pt) 2010-03-30 2022-11-08 Children's Hospital & Research Center At Oakland Composição imunogênica, seu uso, proteína de ligação ao fator h de ocorrência não natural, e célula bacteriana geneticamente modificada
EP2861247B1 (en) * 2012-06-14 2020-12-09 GlaxoSmithKline Biologicals SA Vaccines for serogroup x meningococcus
GB201215005D0 (en) 2012-08-23 2012-10-10 Isis Innovation Stabilised meningitis vaccine
RS61246B1 (sr) 2014-02-28 2021-01-29 Glaxosmithkline Biologicals Sa Modifikovani meningokokni fhbp polipeptidi
EP2916512B1 (en) 2014-03-07 2016-08-24 Mitsubishi Electric R&D Centre Europe B.V. Method for classifying a TCP connection carrying HTTP traffic as a trusted or an untrusted TCP connection
CN106795208A (zh) 2014-07-17 2017-05-31 葛兰素史密丝克莱恩生物有限公司 修饰的脑膜炎球菌fHbp多肽
EA038940B1 (ru) 2014-07-17 2021-11-12 Глаксосмитклайн Байолоджикалс С.А. Менингококковые вакцины

Also Published As

Publication number Publication date
JP2017522319A (ja) 2017-08-10
WO2016008961A1 (en) 2016-01-21
KR20170029615A (ko) 2017-03-15
US20180214531A1 (en) 2018-08-02
AU2019201131A1 (en) 2019-03-07
BE1022878B1 (fr) 2016-09-30
CA2954729C (en) 2023-08-22
SG10201900041VA (en) 2019-02-27
AR101225A1 (es) 2016-11-30
SG11201610946YA (en) 2017-01-27
CN106659776A (zh) 2017-05-10
BE1022878A1 (fr) 2016-09-30
JP2020117523A (ja) 2020-08-06
CN113827712A (zh) 2021-12-24
MX2017000775A (es) 2017-05-04
AU2019201131C1 (en) 2021-03-18
US20230414736A1 (en) 2023-12-28
EA038940B1 (ru) 2021-11-12
KR102626831B1 (ko) 2024-01-22
AU2015289193A1 (en) 2017-02-02
IL249823A0 (en) 2017-03-30
JP6687597B2 (ja) 2020-04-22
AU2019201131B2 (en) 2020-08-27
BR112017000519A2 (pt) 2017-11-21
EP3169358A1 (en) 2017-05-24
IL249823B (en) 2022-07-01
JP7074793B2 (ja) 2022-05-24
CA2954729A1 (en) 2016-01-21
KR20230012100A (ko) 2023-01-25
US11707513B2 (en) 2023-07-25

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