EA201491581A1 - Везикулярные композиции - Google Patents
Везикулярные композицииInfo
- Publication number
- EA201491581A1 EA201491581A1 EA201491581A EA201491581A EA201491581A1 EA 201491581 A1 EA201491581 A1 EA 201491581A1 EA 201491581 A EA201491581 A EA 201491581A EA 201491581 A EA201491581 A EA 201491581A EA 201491581 A1 EA201491581 A1 EA 201491581A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- композиции
- везикулярные
- relates
- rosacea
- vesicular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Fodder In General (AREA)
Abstract
Настоящее изобретение относится к везикулярным композициям для лечения розацеа. Оно также относится к способу лечения розацеа, включающему введение везикулярной композиции согласно изобретению.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1205642.0A GB201205642D0 (en) | 2012-03-29 | 2012-03-29 | Vesicular formulations |
PCT/EP2013/056694 WO2013144289A1 (en) | 2012-03-29 | 2013-03-28 | Vesicular formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201491581A1 true EA201491581A1 (ru) | 2015-02-27 |
EA038899B1 EA038899B1 (ru) | 2021-11-03 |
Family
ID=46159988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201491581A EA038899B1 (ru) | 2012-03-29 | 2013-03-28 | Везикулярные композиции |
Country Status (19)
Country | Link |
---|---|
US (1) | US9555051B2 (ru) |
EP (1) | EP2830630A1 (ru) |
JP (1) | JP2015511618A (ru) |
KR (1) | KR20150004798A (ru) |
CN (1) | CN104349782A (ru) |
AU (1) | AU2013241701A1 (ru) |
BR (1) | BR112014024033A8 (ru) |
CA (1) | CA2867749A1 (ru) |
CL (1) | CL2014002547A1 (ru) |
CO (1) | CO7121334A2 (ru) |
EA (1) | EA038899B1 (ru) |
GB (2) | GB201205642D0 (ru) |
IL (1) | IL234747A0 (ru) |
IN (1) | IN2014DN07913A (ru) |
MX (1) | MX2014011516A (ru) |
NZ (1) | NZ700472A (ru) |
PH (1) | PH12014502065A1 (ru) |
SG (1) | SG11201406144TA (ru) |
WO (1) | WO2013144289A1 (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120232034A1 (en) | 2009-08-21 | 2012-09-13 | Henk-Andre Kroon | Vesicular formulations |
BR112017013471A2 (pt) * | 2014-12-23 | 2018-02-27 | Camurus Ab | Pré-formulação, formulação farmacêutica, composição de depósito, métodos para administração de um agente bioativo a um organismo humano ou não humano, para preparação de uma composição cristalina líquida, para tratamento ou profilaxia de um indivíduo animal não humano ou humano, para administração de uma pré-formulação para um sujeito que dela necessita, processo para formação de uma pré- formulação, uso de uma mistura cristalina não líquida de baixa viscosidade, dispositivo de administração pré-preenchido, e, kit. |
PL3316856T3 (pl) | 2015-06-30 | 2021-10-25 | Sequessome Technology Holdings Limited | Zmieszane formulacje |
EP4324460A3 (en) | 2017-09-15 | 2024-04-24 | Dyve Biosciences, Inc. | Sodium bicarbonate for use in the treatment of gout and related disorders |
EP4297743A1 (en) * | 2021-02-25 | 2024-01-03 | Exinov | Emulsion for use in the treatment of rosacea |
Family Cites Families (63)
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JPS60136511A (ja) | 1983-12-26 | 1985-07-20 | Eisai Co Ltd | 高尿酸血症治療剤 |
EP0238554A4 (en) | 1985-09-27 | 1987-10-27 | Univ California | LIPOSOME SYSTEM FOR TRANSDERMAL DRUG ADMINISTRATION. |
JPS6295134A (ja) | 1985-10-21 | 1987-05-01 | Nippon Saafuakutanto Kogyo Kk | リポソ−ムの製造法 |
US5015483A (en) | 1989-02-09 | 1991-05-14 | Nabisco Brands, Inc. | Liposome composition for the stabilization of oxidizable substances |
US5498607A (en) | 1990-07-30 | 1996-03-12 | University Of Miami | Treatment for hypercholesterolemia |
CA2067754C (en) | 1990-08-24 | 2002-06-04 | Gregor Cevc | Preparation for the application of agents in mini-droplets |
US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
US5498420A (en) | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
JPH08509202A (ja) | 1992-07-08 | 1996-10-01 | ディアノルム―ゲレーテ・ゲー・マイエルホファー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | リポソーム、それを調製する方法及び薬調製におけるその用途 |
FR2714382B1 (fr) | 1993-12-27 | 1996-02-02 | Roussel Uclaf | Phospholipides vecteur de molécule active, leur préparation et leur utilisation dans des compositions cosmétiques ou dermatologiques. |
DE4447287C1 (de) | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
US5902604A (en) | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
FR2767691B1 (fr) | 1997-08-27 | 2000-02-18 | Oreal | Utilisation d'une dispersion a base de vehicules lipidiques comme composition anti-inflammatoire |
BR9814214B1 (pt) * | 1997-11-19 | 2010-07-13 | composição com ácido azeláico. | |
US6165997A (en) | 1997-11-20 | 2000-12-26 | Statens Serum Institut | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
KR20010106462A (ko) | 1998-09-01 | 2001-11-29 | 체에베체 그레고르 | 배리어를 가로지른 대전 침투제의 전기적으로 제어된수송 |
AU770803B2 (en) | 1998-12-23 | 2004-03-04 | Idea Ag | Improved formulation for topical non-invasive application in vivo |
PT1031346E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Vacinacao nao invasiva atraves da pele |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
AU5409699A (en) | 1999-07-05 | 2001-01-22 | Idea Ag | A method for the improvement of transport across adaptable semi-permeable barriers |
US6248728B1 (en) | 2000-03-10 | 2001-06-19 | Kansas State University Research Foundation | Phosphatidylcholine compositions and methods for lowering intestinal absorption and plasma levels of cholesterol |
US6191121B1 (en) | 2000-04-06 | 2001-02-20 | Nicholas V. Perricone | Treatment of skin damage using polyenylphosphatidylcholine |
EP1272160B1 (en) | 2000-04-12 | 2007-01-17 | Liplasome Pharma A/S | Lipid-based drug delivery systems for topical application |
TWI281407B (en) | 2000-09-18 | 2007-05-21 | Vasogen Ireland Ltd | Apoptosis-mimicking synthetic entities and use thereof in medical treatment |
WO2002062316A1 (de) | 2001-02-08 | 2002-08-15 | Vectron Therapeutics Ag | Invasomen zur therapie von erkrankungen, ihre herstellung und verwendung |
BR0210104A (pt) | 2001-05-31 | 2004-06-08 | Pharmacia Corp | Composição inibidora seletiva de ciclooxigenase-2 permeável à pele |
CA2451245A1 (en) | 2001-06-25 | 2003-01-03 | Depuy International Limited | Liposomal encapsulation of glycosaminoglycans for the treatment of arthritic joints |
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CA2498938A1 (en) | 2002-10-11 | 2004-04-22 | Idea Ag | Aggregate with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
JP2004131432A (ja) | 2002-10-11 | 2004-04-30 | Kumamoto Technology & Industry Foundation | 悪性腫瘍抑制剤 |
US20040105881A1 (en) | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
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BRPI0412882A (pt) | 2003-07-21 | 2006-10-03 | Vasogen Ireland Ltd | uso de uma quantidade de corpos farmaceuticamente aceitáveis que portam um número eficaz de grupos contendo fosfato |
JP2005179313A (ja) | 2003-12-24 | 2005-07-07 | Shu Uemura:Kk | 皮膚化粧料用基剤の製造方法および皮膚化粧料 |
US7476432B2 (en) | 2004-05-28 | 2009-01-13 | Tecton Products | Phosphorescent pultrusion |
US20080095722A1 (en) | 2004-11-12 | 2008-04-24 | Idea Ag | Extended Surface Aggregates in the Treatment of Skin Conditions |
WO2006086992A2 (en) | 2005-02-18 | 2006-08-24 | Liplasome Pharma A/S | Drug delivery systems containing phqspholipase a2 degradable lipid prodrug derivatives and the therapeutic uses thereof as. e.g. wound healing agents and peroxisome proliferator activated receptor ligands |
US20070042008A1 (en) | 2005-08-18 | 2007-02-22 | Bodybio, Inc. | Compositions containing phosphatidylcholine and essential fatty acids |
JP5432525B2 (ja) | 2005-08-29 | 2014-03-05 | セプシキュア、リミテッド、ライアビリティ、カンパニー | グラム陽性菌によって引き起こされる状態の治療又は予防方法 |
NZ569068A (en) | 2005-12-20 | 2011-11-25 | Cenestra Llc | Omega 3 fatty acid formulations of EPA and DHA |
JP5009547B2 (ja) | 2006-03-31 | 2012-08-22 | 株式会社コーセー | 顔料とリポソームを含む化粧料 |
US7544375B1 (en) | 2006-06-12 | 2009-06-09 | Swiss Skin Repair, Inc. | Composition |
CN101541308B (zh) | 2006-09-28 | 2012-02-01 | 哈达斯特医疗研究服务和开发有限公司 | 甘油磷脂用于关节润滑的用途 |
JP4732307B2 (ja) | 2006-11-20 | 2011-07-27 | 株式会社アンズコーポレーション | ナノエマルション及びそれを配合した化粧料 |
US20100130611A1 (en) | 2006-12-20 | 2010-05-27 | Cenestra Llc | Omega 3 fatty acid formulations |
EP1938801A1 (en) | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
US9511016B2 (en) | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
ITVR20080006A1 (it) | 2008-01-23 | 2009-07-24 | David Ceretta | Apparato per la realizzazione di elementi d'impasto |
ES2335636B1 (es) | 2008-02-29 | 2011-05-11 | Lipotec, S.A. | Composicion cosmetica o dermofarmaceutica de micelas mixtas. |
JP2009256331A (ja) | 2008-03-25 | 2009-11-05 | Nagase Chemtex Corp | 高尿酸血症、又は痛風の予防、改善、又は治療剤 |
US20100105139A1 (en) | 2008-10-27 | 2010-04-29 | Remco Alexander Spanjaard | Ligand Targeted Nanocapsules for the delivery of RNAi and other Agents |
MX2011008204A (es) | 2009-02-05 | 2011-12-06 | Targeted Delivery Technologies Ltd | Metodos para reducir la proliferacion y viabilidad de los agentes microbianos. |
CN102639113A (zh) | 2009-06-03 | 2012-08-15 | J·C·梅奥 | 用于治疗深部组织疼痛的制剂 |
US20120232034A1 (en) * | 2009-08-21 | 2012-09-13 | Henk-Andre Kroon | Vesicular formulations |
EP2382994A1 (en) | 2010-04-26 | 2011-11-02 | Maurizio Victor Cattaneo | Ligand targeted nanocapsules for the delivery of RNAi and other agents |
US8741373B2 (en) | 2010-06-21 | 2014-06-03 | Virun, Inc. | Compositions containing non-polar compounds |
US20120045405A1 (en) | 2010-08-18 | 2012-02-23 | Gilman Miles E | Under eye cream |
GB201206486D0 (en) | 2012-04-12 | 2012-05-30 | Sequessome Technology Holdings Ltd | Vesicular formulations and uses thereof |
GB201208409D0 (en) | 2012-05-14 | 2012-06-27 | Sequessome Technology Holdings Ltd | Vesicular formulations, kits and uses |
GB201208384D0 (en) | 2012-05-14 | 2012-06-27 | Sequessome Technology Holdings Ltd | Vesicular formulations, uses and methods |
KR102325654B1 (ko) | 2013-07-31 | 2021-11-12 | 시퀘솜 네크놀로지 홀딩스 리미티드 | 소포체 |
-
2012
- 2012-03-29 GB GBGB1205642.0A patent/GB201205642D0/en not_active Ceased
-
2013
- 2013-03-28 AU AU2013241701A patent/AU2013241701A1/en not_active Abandoned
- 2013-03-28 CA CA2867749A patent/CA2867749A1/en not_active Abandoned
- 2013-03-28 KR KR1020147027498A patent/KR20150004798A/ko not_active Application Discontinuation
- 2013-03-28 WO PCT/EP2013/056694 patent/WO2013144289A1/en active Application Filing
- 2013-03-28 US US14/388,469 patent/US9555051B2/en active Active
- 2013-03-28 JP JP2015502351A patent/JP2015511618A/ja active Pending
- 2013-03-28 SG SG11201406144TA patent/SG11201406144TA/en unknown
- 2013-03-28 IN IN7913DEN2014 patent/IN2014DN07913A/en unknown
- 2013-03-28 CN CN201380027033.9A patent/CN104349782A/zh active Pending
- 2013-03-28 NZ NZ700472A patent/NZ700472A/en unknown
- 2013-03-28 BR BR112014024033A patent/BR112014024033A8/pt not_active IP Right Cessation
- 2013-03-28 MX MX2014011516A patent/MX2014011516A/es unknown
- 2013-03-28 EP EP13712801.3A patent/EP2830630A1/en not_active Ceased
- 2013-03-28 GB GB1419075.5A patent/GB2515440B/en active Active
- 2013-03-28 EA EA201491581A patent/EA038899B1/ru unknown
-
2014
- 2014-09-17 PH PH12014502065A patent/PH12014502065A1/en unknown
- 2014-09-18 IL IL234747A patent/IL234747A0/en unknown
- 2014-09-25 CL CL2014002547A patent/CL2014002547A1/es unknown
- 2014-10-28 CO CO14238690A patent/CO7121334A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
US20150057249A1 (en) | 2015-02-26 |
GB2515440B (en) | 2017-02-08 |
CO7121334A2 (es) | 2014-11-20 |
WO2013144289A1 (en) | 2013-10-03 |
CN104349782A (zh) | 2015-02-11 |
KR20150004798A (ko) | 2015-01-13 |
EP2830630A1 (en) | 2015-02-04 |
JP2015511618A (ja) | 2015-04-20 |
SG11201406144TA (en) | 2014-10-30 |
GB201419075D0 (en) | 2014-12-10 |
GB2515440A (en) | 2014-12-24 |
US9555051B2 (en) | 2017-01-31 |
CL2014002547A1 (es) | 2015-03-27 |
CA2867749A1 (en) | 2013-10-03 |
EA038899B1 (ru) | 2021-11-03 |
NZ700472A (en) | 2016-02-26 |
IL234747A0 (en) | 2014-11-30 |
BR112014024033A8 (pt) | 2017-07-25 |
MX2014011516A (es) | 2015-04-08 |
GB201205642D0 (en) | 2012-05-16 |
BR112014024033A2 (ru) | 2017-06-20 |
AU2013241701A1 (en) | 2014-10-16 |
IN2014DN07913A (ru) | 2015-04-24 |
PH12014502065A1 (en) | 2014-12-10 |
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